Expression alterations define unique molecular characteristics of spinal ependymomas

por Lourdusamy, Anbarasu, Rahman, Ruman, Grundy, Richard G.
Publicado 2015

Pediatric ependymomas: destined to recur?

por Ritzmann, Timothy A, Kilday, John-Paul, Grundy, Richard G
Publicado 2021

The therapeutic potential of targeting the PI3K pathway in pediatric brain tumors

por Rogers, Hazel A., Estranero, Jasper, Gudka, Keshni, Grundy, Richard G.
Publicado 2016

Endothelial-like malignant glioma cells in dynamic three dimensional culture identifies a role for VEGF and FGFR in a tumor-derived angiogenic response

por Smith, Stuart J., Ward, Jennifer H., Tan, Christopher, Grundy, Richard G., Rahman, Ruman
Publicado 2015

THER-03. IN VITRO EVALUATION OF THE EFFECT OF CANNABIDIOL ON PAEDIATRIC BRAIN TUMOUR CELL LINES USING A PULSED TREATMENT REGIME

por Faulkes, Sophie, Lockwood, George, O’Sullivan, Saoirse E, Grundy, Richard G, Storer, Lisa C D
Publicado 2020

The Molecular Landscape of Medulloblastoma in Teenagers and Young Adults

por Mohammed, Omar J., Cebrero, Maria Estevez, Ahmad, Omar, Peet, Andrew, Grundy, Richard G., Lourdusamy, Anbarasu
Publicado 2022

Serial MR diffusion to predict treatment response in high-grade pediatric brain tumors: a comparison of regional and voxel-based diffusion change metrics

por Rodriguez Gutierrez, Daniel, Manita, Muftah, Jaspan, Tim, Dineen, Robert A., Grundy, Richard G., Auer, Dorothee P.
Publicado 2013

The prognostic role of intragenic copy number breakpoints and identification of novel fusion genes in paediatric high grade glioma

por Carvalho, Diana, Mackay, Alan, Bjerke, Lynn, Grundy, Richard G, Lopes, Celeste, Reis, Rui M, Jones, Chris
Publicado 2014

Transcriptomic analysis in pediatric spinal ependymoma reveals distinct molecular signatures

por Lourdusamy, Anbarasu, Luo, Li Z., Storer, Lisa CD., Cohen, Kenneth J., Resar, Linda, Grundy, Richard G.
Publicado 2017

High resolution magic angle spinning 1H NMR of childhood brain and nervous system tumours

por Wilson, Martin, Davies, Nigel P, Brundler, Marie-Anne, McConville, Carmel, Grundy, Richard G, Peet, Andrew C
Publicado 2009

Texture analysis of T(1)- and T(2)-weighted MR images and use of probabilistic neural network to discriminate posterior fossa tumours in children

por Orphanidou-Vlachou, Eleni, Vlachos, Nikolaos, Davies, Nigel P, Arvanitis, Theodoros N, Grundy, Richard G, Peet, Andrew C
Publicado 2014

THER-04. IS THERE A ROLE FOR CANNABIDIOL IN THE TREATMENT OF CHILDHOOD BRAIN TUMOURS?

por Lockwood, George, Hatfield, Amelia, Mabrouk, Mohamed, O’Sullivan, Saoirse E, Grundy, Richard G, Storer, Lisa C D
Publicado 2020

CD105 (Endoglin) exerts prognostic effects via its role in the microvascular niche of paediatric high grade glioma

por Smith, Stuart J., Tilly, Hanna, Ward, Jennifer H., Macarthur, Donald C., Lowe, James, Coyle, Beth, Grundy, Richard G.
Publicado 2012

BLBP Is Both a Marker for Poor Prognosis and a Potential Therapeutic Target in Paediatric Ependymoma

por Sabnis, Durgagauri H., Liu, Jo-Fen, Simmonds, Lucy, Blackburn, Sophie, Grundy, Richard G., Kerr, Ian D., Coyle, Beth
Publicado 2021

EPEN-43. TARGETING INTRA-TUMOUR HETEROGENEITY IN PAEDIATRIC EPENDYMOMA: AN INTEGRATED OMICS STUDY TOWARDS PATIENT-TAILORED THERAPY

por Pandele, Alina, Woodward, Alison, MacArthur, Donald, Kamaly-Asl, Ian, Barrett, David A, Grundy, Richard G, Kim, Dong-Hyun, Rahman, Ruman
Publicado 2020

Integrative molecular characterization of pediatric spinal ependymoma: the UK Children’s Cancer and Leukaemia Group study

por Ahmad, Omar, Chapman, Rebecca, Storer, Lisa C, Luo, Li, Heath, Paul R, Resar, Linda, Cohen, Kenneth J, Grundy, Richard G, Lourdusamy, Anbarasu
Publicado 2021

Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion

por Bishop, Eleanor, Dimitrova, Monika, Froggatt, Alexander, Estevez-Cebrero, Maria, Storer, Lisa C. D., Mussai, Francis, Paine, Simon, Grundy, Richard G., Dandapani, Madhumita
Publicado 2022

Overcoming multiple drug resistance mechanisms in medulloblastoma

por Othman, Ramadhan T, Kimishi, Ioanna, Bradshaw, Tracey D, Storer, Lisa CD, Korshunov, Andrey, Pfister, Stefan M, Grundy, Richard G, Kerr, Ian D, Coyle, Beth
Publicado 2014

Supratentorial and spinal pediatric ependymomas display a hypermethylated phenotype which includes the loss of tumor suppressor genes involved in the control of cell growth and dea...

por Rogers, Hazel A., Kilday, John-Paul, Mayne, Cerys, Ward, Jennifer, Adamowicz-Brice, Martyna, Schwalbe, Ed C., Clifford, Steven C., Coyle, Beth, Grundy, Richard G.
Publicado 2011

Magnetic resonance spectroscopy metabolite profiles predict survival in paediatric brain tumours

por Wilson, Martin, Cummins, Carole L., MacPherson, Lesley, Sun, Yu, Natarajan, Kal, Grundy, Richard G., Arvanitis, Theodoros N., Kauppinen, Risto A., Peet, Andrew C.
Publicado 2013