Inhibition of KIT-Glycosylation by 2-Deoxyglucose Abrogates KIT-Signaling and Combination with ABT-263 Synergistically Induces Apoptosis in Gastrointestinal Stromal Tumor

por Mühlenberg, Thomas, Grunewald, Susanne, Treckmann, Jürgen, Podleska, Lars, Schuler, Martin, Fletcher, Jonathan A., Bauer, Sebastian
Publicado 2015

Inhibitor of Apoptosis Proteins (IAPs) are commonly dysregulated in GIST and can be pharmacologically targeted to enhance the pro-apoptotic activity of imatinib

por Falkenhorst, Johanna, Grunewald, Susanne, Mühlenberg, Thomas, Marino-Enriquez, Adrian, Reis, Anna-Carina, Corless, Christopher, Heinrich, Michael, Treckmann, Jürgen, Podleska, Lars Erik, Schuler, Martin, Fletcher, Jonathan Alfred, Bauer, Sebastian
Publicado 2016

Evaluation of the Effect of Photodynamic Therapy on CAM-Grown Sarcomas

por Kerkhoff, Maximilian, Grunewald, Susanne, Schaefer, Christiane, Zöllner, Stefan K., Plaumann, Pauline, Busch, Maike, Dünker, Nicole, Ketzer, Julia, Kersting, Josephine, Bauer, Sebastian, Hardes, Jendrik, Streitbürger, Arne, Dirksen, Uta, Hartmann, Wolfgang, Guder, Wiebke K.
Publicado 2023

Plasma Sequencing for Patients with GIST—Limitations and Opportunities in an Academic Setting

por Falkenhorst, Johanna, Grunewald, Susanne, Krzeciesa, Dawid, Herold, Thomas, Ketzer, Julia, Christoff, Miriam, Hamacher, Rainer, Kostbade, Karina, Treckmann, Jürgen, Köster, Johannes, Farzaliyev, Farhad, Fletcher, Benjamin Samulon, Dieckmann, Nils, Kaths, Moritz, Mühlenberg, Thomas, Schildhaus, Hans-Ulrich, Bauer, Sebastian
Publicado 2022

MAX inactivation is an early event in GIST development that regulates p16 and cell proliferation

por Schaefer, Inga-Marie, Wang, Yuexiang, Liang, Cher-wei, Bahri, Nacef, Quattrone, Anna, Doyle, Leona, Mariño-Enríquez, Adrian, Lauria, Alexandra, Zhu, Meijun, Debiec-Rychter, Maria, Grunewald, Susanne, Hechtman, Jaclyn F., Dufresne, Armelle, Antonescu, Cristina R., Beadling, Carol, Sicinska, Ewa T., van de Rijn, Matt, Demetri, George D., Ladanyi, Marc, Corless, Christopher L., Heinrich, Michael C., Raut, Chandrajit P., Bauer, Sebastian, Fletcher, Jonathan A.
Publicado 2017