DJ-1: A promising therapeutic candidate for ischemia-reperfusion injury

por De Lazzari, Federica, Prag, Hiran A., Gruszczyk, Anja V., Whitworth, Alexander J., Bisaglia, Marco
Publicado 2021

Mitochondrial mechanisms and therapeutics in ischaemia reperfusion injury

por Martin, Jack L., Gruszczyk, Anja V., Beach, Timothy E., Murphy, Michael P., Saeb-Parsy, Kourosh
Publicado 2018

Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury

por Bundgaard, Amanda, James, Andrew M., Gruszczyk, Anja V., Martin, Jack, Murphy, Michael P., Fago, Angela
Publicado 2019

Microtubule-dependent and independent roles of spastin in lipid droplet dispersion and biogenesis

por Tadepalle, Nimesha, Robers, Lennart, Veronese, Matteo, Zentis, Peter, Babatz, Felix, Brodesser, Susanne, Gruszczyk, Anja V, Schauss, Astrid, Höning, Stefan, Rugarli, Elena I
Publicado 2020

Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly

por Hinchy, Elizabeth C., Gruszczyk, Anja V., Willows, Robin, Navaratnam, Naveenan, Hall, Andrew R., Bates, Georgina, Bright, Thomas P., Krieg, Thomas, Carling, David, Murphy, Michael P.
Publicado 2018

Rapid fractionation of mitochondria from mouse liver and heart reveals in vivo metabolite compartmentation

por Allen, Fay M., Costa, Ana S. H., Gruszczyk, Anja V., Bates, Georgina R., Prag, Hiran A., Nikitopoulou, Efterpi, Viscomi, Carlo, Frezza, Christian, James, Andrew M., Murphy, Michael P.
Publicado 2022

Mitochondrial metabolism and bioenergetic function in an anoxic isolated adult mouse cardiomyocyte model of in vivo cardiac ischemia-reperfusion injury

por Gruszczyk, Anja V., Casey, Alva M., James, Andrew M., Prag, Hiran A., Burger, Nils, Bates, Georgina R., Hall, Andrew R., Allen, Fay M., Krieg, Thomas, Saeb-Parsy, Kourosh, Murphy, Michael P.
Publicado 2022

Selective mitochondrial superoxide generation in vivo is cardioprotective through hormesis

por Antonucci, Salvatore, Mulvey, John F., Burger, Nils, Di Sante, Moises, Hall, Andrew R., Hinchy, Elizabeth C., Caldwell, Stuart T., Gruszczyk, Anja V., Deshwal, Soni, Hartley, Richard C., Kaludercic, Nina, Murphy, Michael P., Di Lisa, Fabio, Krieg, Thomas
Publicado 2019

AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology

por Tilokani, Lisa, Russell, Fiona M., Hamilton, Stevie, Virga, Daniel M., Segawa, Mayuko, Paupe, Vincent, Gruszczyk, Anja V., Protasoni, Margherita, Tabara, Luis-Carlos, Johnson, Mark, Anand, Hanish, Murphy, Michael P., Hardie, D. Grahame, Polleux, Franck, Prudent, Julien
Publicado 2022

Targeting succinate dehydrogenase with malonate ester prodrugs decreases renal ischemia reperfusion injury

por Beach, Timothy E., Prag, Hiran A., Pala, Laura, Logan, Angela, Huang, Margaret M., Gruszczyk, Anja V., Martin, Jack L., Mahbubani, Krishnaa, Hamed, Mazin O., Hosgood, Sarah A., Nicholson, Michael L., James, Andrew M., Hartley, Richard C., Murphy, Michael P., Saeb-Parsy, Kourosh
Publicado 2020

Mechanism of succinate efflux upon reperfusion of the ischaemic heart

por Prag, Hiran A, Gruszczyk, Anja V, Huang, Margaret M, Beach, Timothy E, Young, Timothy, Tronci, Laura, Nikitopoulou, Efterpi, Mulvey, John F, Ascione, Raimondo, Hadjihambi, Anna, Shattock, Michael J, Pellerin, Luc, Saeb-Parsy, Kourosh, Frezza, Christian, James, Andrew M, Krieg, Thomas, Murphy, Michael P, Aksentijević, Dunja
Publicado 2020

Succinate accumulation drives ischaemia-reperfusion injury during organ transplantation

por Martin, Jack L., Costa, Ana S. H., Gruszczyk, Anja V., Beach, Timothy E., Allen, Fay M., Prag, Hiran A., Hinchy, Elizabeth C., Mahbubani, Krishnaa, Hamed, Mazin, Tronci, Laura, Nikitopoulou, Efterpi, James, Andrew M., Krieg, Thomas, Robinson, Alan J., Huang, Margaret H., Caldwell, Stuart T., Logan, Angela, Pala, Laura, Hartley, Richard C., Frezza, Christian, Saeb-Parsy, Kourosh, Murphy, Michael P.
Publicado 2019

Confirmation of the Cardioprotective Effect of MitoGamide in the Diabetic Heart

por Park, Min, Nishimura, Takanori, Baeza-Garza, Carlos D., Caldwell, Stuart T., Pun, Pamela Boon Li, Prag, Hiran A., Young, Tim, Sauchanka, Olga, Logan, Angela, Forkink, Marleen, Gruszczyk, Anja V., Prime, Tracy A., Arndt, Sabine, Naudi, Alba, Pamplona, Reinald, Coughlan, Melinda T., Tate, Mitchel, Ritchie, Rebecca H., Caicci, Federico, Kaludercic, Nina, Di Lisa, Fabio, Smith, Robin A. J., Hartley, Richard C., Murphy, Michael P., Krieg, Thomas
Publicado 2020

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders

por Taylor, Jenny C, Martin, Hilary C, Lise, Stefano, Broxholme, John, Cazier, Jean-Baptiste, Rimmer, Andy, Kanapin, Alexander, Lunter, Gerton, Fiddy, Simon, Allan, Chris, Aricescu, A. Radu, Attar, Moustafa, Babbs, Christian, Becq, Jennifer, Beeson, David, Bento, Celeste, Bignell, Patricia, Blair, Edward, Buckle, Veronica J, Bull, Katherine, Cais, Ondrej, Cario, Holger, Chapel, Helen, Copley, Richard R, Cornall, Richard, Craft, Jude, Dahan, Karin, Davenport, Emma E, Dendrou, Calliope, Devuyst, Olivier, Fenwick, Aimée L, Flint, Jonathan, Fugger, Lars, Gilbert, Rodney D, Goriely, Anne, Green, Angie, Greger, Ingo H., Grocock, Russell, Gruszczyk, Anja V, Hastings, Robert, Hatton, Edouard, Higgs, Doug, Hill, Adrian, Holmes, Chris, Howard, Malcolm, Hughes, Linda, Humburg, Peter, Johnson, David, Karpe, Fredrik, Kingsbury, Zoya, Kini, Usha, Knight, Julian C, Krohn, Jonathan, Lamble, Sarah, Langman, Craig, Lonie, Lorne, Luck, Joshua, McCarthy, Davis, McGowan, Simon J, McMullin, Mary Frances, Miller, Kerry A, Murray, Lisa, Németh, Andrea H, Nesbit, M Andrew, Nutt, David, Ormondroyd, Elizabeth, Oturai, Annette Bang, Pagnamenta, Alistair, Patel, Smita Y, Percy, Melanie, Petousi, Nayia, Piazza, Paolo, Piret, Sian E, Polanco-Echeverry, Guadalupe, Popitsch, Niko, Powrie, Fiona, Pugh, Chris, Quek, Lynn, Robbins, Peter A, Robson, Kathryn, Russo, Alexandra, Sahgal, Natasha, van Schouwenburg, Pauline A, Schuh, Anna, Silverman, Earl, Simmons, Alison, Sørensen, Per Soelberg, Sweeney, Elizabeth, Taylor, John, Thakker, Rajesh V, Tomlinson, Ian, Trebes, Amy, Twigg, Stephen RF, Uhlig, Holm H, Vyas, Paresh, Vyse, Tim, Wall, Steven A, Watkins, Hugh, Whyte, Michael P, Witty, Lorna, Wright, Ben, Yau, Chris, Buck, David, Humphray, Sean, Ratcliffe, Peter J, Bell, John I, Wilkie, Andrew OM, Bentley, David, Donnelly, Peter, McVean, Gilean
Publicado 2015