Sulfasalazine: a risk factor for severe COVID-19?

por Konig, Maximilian F, Grzes, Katarzyna M, Robinson, Philip C, Pearce, Edward J
Publicado 2022

Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

por Swamy, Mahima, Pathak, Shalini, Grzes, Katarzyna M., Damerow, Sebastian, Sinclair, Linda V., van Aalten, Daan M. F., Cantrell, Doreen A.
Publicado 2016

The cytotoxic T cell proteome and its shaping by mammalian Target of Rapamycin

por Hukelmann, Jens L., Anderson, Karen E., Sinclair, Linda V., Grzes, Katarzyna M., Murillo, Alejandro Brenes, Hawkins, Phillip T., Stephens, Len R., Lamond, Angus I., Cantrell, Doreen A.
Publicado 2015

Phenformin, But Not Metformin, Delays Development of T Cell Acute Lymphoblastic Leukemia/Lymphoma via Cell-Autonomous AMPK Activation

por Vara-Ciruelos, Diana, Dandapani, Madhumita, Russell, Fiona M., Grzes, Katarzyna M., Atrih, Abdelmadjid, Foretz, Marc, Viollet, Benoit, Lamont, Douglas J., Cantrell, Doreen A., Hardie, D. Grahame
Publicado 2019

Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition

por Frost, Julianty, Galdeano, Carles, Soares, Pedro, Gadd, Morgan S., Grzes, Katarzyna M., Ellis, Lucy, Epemolu, Ola, Shimamura, Satoko, Bantscheff, Marcus, Grandi, Paola, Read, Kevin D., Cantrell, Doreen A., Rocha, Sonia, Ciulli, Alessio
Publicado 2016

Loss of beta2-integrin-mediated cytoskeletal linkage reprograms dendritic cells to a mature migratory phenotype

por Morrison, Vicky Louise, James, Martyn John, Grzes, Katarzyna, Cook, Peter, Glass, David Gavin, Savinko, Terhi, Lek, Hwee San, Gawden-Bone, Christian, Watts, Colin, Millington, Owain Richard, MacDonald, Andrew Scott, Fagerholm, Susanna Carola
Publicado 2014

Mitochondrial Integrity Regulated by Lipid Metabolism Is a Cell-Intrinsic Checkpoint for Treg Suppressive Function

por Field, Cameron S., Baixauli, Francesc, Kyle, Ryan L., Puleston, Daniel J., Cameron, Alanna M., Sanin, David E., Hippen, Keli L., Loschi, Michael, Thangavelu, Govindarajan, Corrado, Mauro, Edwards-Hicks, Joy, Grzes, Katarzyna M., Pearce, Edward J., Blazar, Bruce R., Pearce, Erika L.
Publicado 2020

Trained immunity of alveolar macrophages requires metabolic rewiring and type 1 interferon signaling

por Zahalka, Sophie, Starkl, Philipp, Watzenboeck, Martin L., Farhat, Asma, Radhouani, Mariem, Deckert, Florian, Hladik, Anastasiya, Lakovits, Karin, Oberndorfer, Felicitas, Lassnig, Caroline, Strobl, Birgit, Klavins, Kristaps, Matsushita, Mai, Sanin, David E., Grzes, Katarzyna M., Pearce, Edward J., Gorki, Anna-Dorothea, Knapp, Sylvia
Publicado 2022

Metabolic and functional remodeling of colonic macrophages in response to high-fat diet-induced obesity

por Castoldi, Angela, Sanin, David E., van Teijlingen Bakker, Nikki, Aguiar, Cristhiane F., de Brito Monteiro, Lauar, Rana, Nisha, Grzes, Katarzyna M., Kabat, Agnieszka M., Curtis, Jonathan, Cameron, Alanna M., Caputa, George, Antônio de Souza, Tiago, Souto, Fabrício O., Buescher, Joerg M., Edwards-Hicks, Joy, Pearce, Erika L., Pearce, Edward J., Saraiva Camara, Niels Olsen
Publicado 2023

Dynamic Cardiolipin Synthesis Is Required for CD8(+) T Cell Immunity

por Corrado, Mauro, Edwards-Hicks, Joy, Villa, Matteo, Flachsmann, Lea J., Sanin, David E., Jacobs, Maaike, Baixauli, Francesc, Stanczak, Michal, Anderson, Eve, Azuma, Mai, Quintana, Andrea, Curtis, Jonathan D., Clapes, Thomas, Grzes, Katarzyna M., Kabat, Agnieszka M., Kyle, Ryan, Patterson, Annette E., Geltink, Ramon Klein, Amulic, Borko, Steward, Colin G., Strathdee, Douglas, Trompouki, Eirini, O’Sullivan, David, Pearce, Edward J., Pearce, Erika L.
Publicado 2020

Fever supports CD8(+) effector T cell responses by promoting mitochondrial translation

por O’Sullivan, David, Stanczak, Michal A., Villa, Matteo, Uhl, Franziska M., Corrado, Mauro, Klein Geltink, Ramon I., Sanin, David E., Apostolova, Petya, Rana, Nisha, Edwards-Hicks, Joy, Grzes, Katarzyna M., Kabat, Agnieszka M., Kyle, Ryan L., Fabri, Mario, Curtis, Jonathan D., Buck, Michael D., Patterson, Annette E., Regina, Annamaria, Field, Cameron S., Baixauli, Francesc, Puleston, Daniel J., Pearce, Edward J., Zeiser, Robert, Pearce, Erika L.
Publicado 2021

Polyamine metabolism is a central determinant of helper T cell lineage fidelity

por Puleston, Daniel J., Baixauli, Francesc, Sanin, David E., Edwards-Hicks, Joy, Villa, Matteo, Kabat, Agnieszka M., Kamiński, Marcin M., Stanckzak, Michal, Weiss, Hauke J., Grzes, Katarzyna M., Piletic, Klara, Field, Cameron S., Corrado, Mauro, Haessler, Fabian, Wang, Chao, Musa, Yaarub, Schimmelpfennig, Lena, Flachsmann, Lea, Mittler, Gerhard, Yosef, Nir, Kuchroo, Vijay K., Buescher, Joerg M., Balabanov, Stefan, Pearce, Edward J., Green, Douglas R., Pearce, Erika L.
Publicado 2021

Polyamines and eIF5A Hypusination Modulate Mitochondrial Respiration and Macrophage Activation

por Puleston, Daniel J., Buck, Michael D., Klein Geltink, Ramon I., Kyle, Ryan L., Caputa, George, O’Sullivan, David, Cameron, Alanna M., Castoldi, Angela, Musa, Yaarub, Kabat, Agnieszka M., Zhang, Ying, Flachsmann, Lea J., Field, Cameron S., Patterson, Annette E., Scherer, Stefanie, Alfei, Francesca, Baixauli, Francesc, Austin, S. Kyle, Kelly, Beth, Matsushita, Mai, Curtis, Jonathan D., Grzes, Katarzyna M., Villa, Matteo, Corrado, Mauro, Sanin, David E., Qiu, Jing, Pällman, Nora, Paz, Katelyn, Maccari, Maria Elena, Blazar, Bruce R., Mittler, Gerhard, Buescher, Joerg M., Zehn, Dietmar, Rospert, Sabine, Pearce, Edward J., Balabanov, Stefan, Pearce, Erika L.
Publicado 2019