The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control

por Guégan, Jean-Philippe, Frémin, Christophe, Baffet, Georges
Publicado 2012

Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and Perspectives

por Peyraud, Florent, Guegan, Jean-Philippe, Bodet, Dominique, Cousin, Sophie, Bessede, Alban, Italiano, Antoine
Publicado 2022

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism

por Guégan, Jean-Philippe, Pollet, Justine, Ginestier, Christophe, Charafe-Jauffret, Emmanuelle, Peter, Marcus E., Legembre, Patrick
Publicado 2021

Antitumor Effects of PRMT5 Inhibition in Sarcomas

por Verbeke, Stéphanie, Bourdon, Aurélien, Guegan, Jean-Philippe, Leroy, Laura, Chaire, Vanessa, Richard, Elodie, Bessede, Alban, Italiano, Antoine
Publicado 2023

Phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced breast cancer

por Cousin, Sophie, Toulmonde, Maud, Kind, Michèle, Guegan, Jean-Philippe, Bessede, Alban, Cantarel, Coralie, Bellera, Carine, Italiano, Antoine
Publicado 2022

Randomized phase 2 trial of intravenous oncolytic virus JX-594 combined with low-dose cyclophosphamide in patients with advanced soft-tissue sarcoma

por Toulmonde, Maud, Cousin, Sophie, Kind, Michèle, Guegan, Jean-Philippe, Bessede, Alban, Le Loarer, Francois, Perret, Raul, Cantarel, Coralie, Bellera, Carine, Italiano, Antoine
Publicado 2022

Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non–Small Cell Lung Cancer

por Bessede, Alban, Peyraud, Florent, Le Moulec, Sylvestre, Cousin, Sophie, Cabart, Mathilde, Chomy, François, Rey, Christophe, Lara, Oren, Odin, Ophélie, Nafia, Imane, Guegan, Jean-Philippe, Italiano, Antoine
Publicado 2023

Pembrolizumab combined with low-dose cyclophosphamide and intra-tumoral injection of the toll-like receptor 4 agonist G100 in patients with advanced pretreated soft tissue sarcoma:...

por Spalato-Ceruso, Mariella, Bouteiller, Fanny, Guegan, Jean-Philippe, Toulmonde, Maud, Bessede, Alban, Kind, Michèle, Cousin, Sophie, Buy, Xavier, Palussiere, Jean, Le Loarer, François, Dadone-Montaudie, Berengere, Pulido, Marina, Italiano, Antoine
Publicado 2022

Spatial transcriptomics of macrophage infiltration in non-small cell lung cancer reveals determinants of sensitivity and resistance to anti-PD1/PD-L1 antibodies

por Larroquette, Mathieu, Guegan, Jean-Philippe, Besse, Benjamin, Cousin, Sophie, Brunet, Maxime, Le Moulec, Sylvestre, Le Loarer, François, Rey, Christophe, Soria, Jean-Charles, Barlesi, Fabrice, Bessede, Alban, Scoazec, Jean-Yves, Soubeyran, Isabelle, Italiano, Antoine
Publicado 2022

CD95/Fas protects triple negative breast cancer from anti-tumor activity of NK cells

por Qadir, Abdul S., Guégan, Jean Philippe, Ginestier, Christophe, Chaibi, Assia, Bessede, Alban, Charafe-Jauffret, Emmanuelle, Macario, Manon, Lavoué, Vincent, Rouge, Thibault de la Motte, Law, Calvin, Vilker, Jacob, Wang, Hongbin, Stroup, Emily, Schipma, Matthew J., Bridgeman, Bryan, Murmann, Andrea E., Ji, Zhe, Legembre, Patrick, Peter, Marcus E.
Publicado 2021