Staphylococcus aureus single-stranded DNA-binding protein SsbA can bind but cannot stimulate PriA helicase

por Huang, Yen-Hua, Guan, Hong-Hsiang, Chen, Chun-Jung, Huang, Cheng-Yang
Publicado 2017

Plumbagin, a Natural Product with Potent Anticancer Activities, Binds to and Inhibits Dihydroorotase, a Key Enzyme in Pyrimidine Biosynthesis

por Guan, Hong-Hsiang, Huang, Yen-Hua, Lin, En-Shyh, Chen, Chun-Jung, Huang, Cheng-Yang
Publicado 2021

Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode

por Guan, Hong-Hsiang, Huang, Yen-Hua, Lin, En-Shyh, Chen, Chun-Jung, Huang, Cheng-Yang
Publicado 2021

Structural Analysis of Saccharomyces cerevisiae Dihydroorotase Reveals Molecular Insights into the Tetramerization Mechanism

por Guan, Hong-Hsiang, Huang, Yen-Hua, Lin, En-Shyh, Chen, Chun-Jung, Huang, Cheng-Yang
Publicado 2021

Ab initio phasing by molecular averaging in real space with new criteria: application to structure determination of a betanodavirus

por Yoshimura, Masato, Chen, Nai-Chi, Guan, Hong-Hsiang, Chuankhayan, Phimonphan, Lin, Chien-Chih, Nakagawa, Atsushi, Chen, Chun-Jung
Publicado 2016

Noncrystallographic symmetry-constrained map obtained by direct density optimization

por Yoshimura, Masato, Chen, Nai-Chi, Guan, Hong-Hsiang, Chuankhayan, Phimonphan, Lin, Chien-Chih, Nakagawa, Atsushi, Chen, Chun-Jung
Publicado 2020

Direct phase selection of initial phases from single-wavelength anomalous dispersion (SAD) for the improvement of electron density and ab initio structure determination

por Chen, Chung-De, Huang, Yen-Chieh, Chiang, Hsin-Lin, Hsieh, Yin-Cheng, Guan, Hong-Hsiang, Chuankhayan, Phimonphan, Chen, Chun-Jung
Publicado 2014

Structures of two elapid snake venom metalloproteases with distinct activities highlight the disulfide patterns in the D domain of ADAMalysin family proteins

por Guan, Hong-Hsiang, Goh, King-Siang, Davamani, Fabian, Wu, Po-Long, Huang, Yen-Wei, Jeyakanthan, Jeyaraman, Wu, Wen-guey, Chen, Chun-Jung
Publicado 2010

Crystal structure of an antigenic outer-membrane protein from Salmonella Typhi suggests a potential antigenic loop and an efflux mechanism

por Guan, Hong-Hsiang, Yoshimura, Masato, Chuankhayan, Phimonphan, Lin, Chien-Chih, Chen, Nai-Chi, Yang, Ming-Chi, Ismail, Asma, Fun, Hoong-Kun, Chen, Chun-Jung
Publicado 2015

Structural insight into the hydrolase and synthase activities of an alkaline α-galactosidase from Arabidopsis from complexes with substrate/product

por Chuankhayan, Phimonphan, Lee, Ruey-Hua, Guan, Hong-Hsiang, Lin, Chein-Chih, Chen, Nai-Chi, Huang, Yen-Chieh, Yoshimura, Masato, Nakagawa, Atsushi, Chen, Chun-Jung
Publicado 2023

Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibitio...

por Lin, Chien-Chih, Chuankhayan, Phimonphan, Chang, Wen-Ni, Kao, Tseng-Ting, Guan, Hong-Hsiang, Fun, Hoong-Kun, Nakagawa, Atsushi, Fu, Tzu-Fun, Chen, Chun-Jung
Publicado 2015

Characterization of Dimeric Interactions within Protrusion-Domain Interfaces of Parallel and X-Shaped Conformations of Macrobrachium rosenbergii Nodavirus: A Theoretical Study Usin...

por Astani, Elahe K., Chen, Nai-Chi, Huang, Yen-Chieh, Ersali, Sara, Lin, Pei-Ju, Guan, Hong-Hsiang, Lin, Chien-Chih, Chuankhayan, Phimonphan, Chen, Chun-Jung
Publicado 2020

Domain swapping and SMYD1 interactions with the PWWP domain of human hepatoma-derived growth factor

por Chen, Li-Ying, Huang, Yen-Chieh, Huang, Shih-Tsung, Hsieh, Yin-Cheng, Guan, Hong-Hsiang, Chen, Nai-Chi, Chuankhayan, Phimonphan, Yoshimura, Masato, Tai, Ming-Hong, Chen, Chun-Jung
Publicado 2018

Crystal Structures of a Piscine Betanodavirus: Mechanisms of Capsid Assembly and Viral Infection

por Chen, Nai-Chi, Yoshimura, Masato, Guan, Hong-Hsiang, Wang, Ting-Yu, Misumi, Yuko, Lin, Chien-Chih, Chuankhayan, Phimonphan, Nakagawa, Atsushi, Chan, Sunney I., Tsukihara, Tomitake, Chen, Tzong-Yueh, Chen, Chun-Jung
Publicado 2015

Structures of honeybee-infecting Lake Sinai virus reveal domain functions and capsid assembly with dynamic motions

por Chen, Nai-Chi, Wang, Chun-Hsiung, Yoshimura, Masato, Yeh, Yi-Qi, Guan, Hong-Hsiang, Chuankhayan, Phimonphan, Lin, Chien-Chih, Lin, Pei-Ju, Huang, Yen-Chieh, Wakatsuki, Soichi, Ho, Meng-Chiao, Chen, Chun-Jung
Publicado 2023

The atomic structures of shrimp nodaviruses reveal new dimeric spike structures and particle polymorphism

por Chen, Nai-Chi, Yoshimura, Masato, Miyazaki, Naoyuki, Guan, Hong-Hsiang, Chuankhayan, Phimonphan, Lin, Chien-Chih, Chen, Shao-Kang, Lin, Pei-Ju, Huang, Yen-Chieh, Iwasaki, Kenji, Nakagawa, Atsushi, Chan, Sunney I., Chen, Chun-Jung
Publicado 2019

Structural insights into the histidine-containing phospho­transfer protein and receiver domain of sensor histidine kinase suggest a complex model in the two-component regulatory sy...

por Chen, Shao-Kang, Guan, Hong-Hsiang, Wu, Pei-Hsun, Lin, Li-Ting, Wu, Meng-Chun, Chang, Hwan-You, Chen, Nai-Chi, Lin, Chien-Chih, Chuankhayan, Phimonphan, Huang, Yen-Chieh, Lin, Pei-Ju, Chen, Chun-Jung
Publicado 2020

Structural insights into the electron/proton transfer pathways in the quinol:fumarate reductase from Desulfovibrio gigas

por Guan, Hong-Hsiang, Hsieh, Yin-Cheng, Lin, Pei-Ju, Huang, Yen-Chieh, Yoshimura, Masato, Chen, Li-Ying, Chen, Shao-Kang, Chuankhayan, Phimonphan, Lin, Chien-Chih, Chen, Nai-Chi, Nakagawa, Atsushi, Chan, Sunney I., Chen, Chun-Jung
Publicado 2018