The roles of prostaglandin F(2) in regulating the expression of matrix metalloproteinase-12 via an insulin growth factor-2-dependent mechanism in sheared chondrocytes

por Guan, Pei-Pei, Ding, Wei-Yan, Wang, Pu
Publicado 2018

Elevating the Levels of Calcium Ions Exacerbate Alzheimer’s Disease via Inducing the Production and Aggregation of β-Amyloid Protein and Phosphorylated Tau

por Guan, Pei-Pei, Cao, Long-Long, Wang, Pu
Publicado 2021

Molecular mechanism of acetylsalicylic acid in improving learning and memory impairment in APP/PS1 transgenic mice by inhibiting the abnormal cell cycle re-entry of neurons

por Guan, Pei-Pei, Ding, Wei-Yan, Wang, Pu
Publicado 2022

Calcium Ions Aggravate Alzheimer’s Disease Through the Aberrant Activation of Neuronal Networks, Leading to Synaptic and Cognitive Deficits

por Guan, Pei-Pei, Cao, Long-Long, Yang, Yi, Wang, Pu
Publicado 2021

Indomethacin Disrupts the Formation of β-Amyloid Plaques via an α2-Macroglobulin-Activating lrp1-Dependent Mechanism

por Guan, Pei-Pei, Yang, Liu-Qing, Xu, Guo-Biao, Wang, Pu
Publicado 2021

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

por Cao, Long-Long, Guan, Pei-Pei, Liang, Yun-Yue, Huang, Xue-Shi, Wang, Pu
Publicado 2019

Rofecoxib Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Alleviating Cyclooxygenase-2-Mediated Mechanisms

por Zou, Yan-Hui, Guan, Pei-Pei, Zhang, Shen-Qing, Guo, Yan-Su, Wang, Pu
Publicado 2020

Aggravation of Alzheimer’s disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells

por Wang, Pu, Guan, Pei-Pei, Wang, Tao, Yu, Xin, Guo, Jian-Jun, Wang, Zhan-You
Publicado 2014

Prostaglandin I(2) Attenuates Prostaglandin E(2)-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism

por Wang, Pu, Guan, Pei-Pei, Yu, Xin, Zhang, Li-Chao, Su, Ya-Nan, Wang, Zhan-You
Publicado 2016

Downregulating expression of OPTN elevates neuroinflammation via AIM2 inflammasome- and RIPK1-activating mechanisms in APP/PS1 transgenic mice

por Cao, Long-Long, Guan, Pei-Pei, Zhang, Shen-Qing, Yang, Yi, Huang, Xue-Shi, Wang, Pu
Publicado 2021

Addendum: Prostaglandin I(2) Attenuates Prostaglandin E(2)-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism

por Wang, Pu, Guan, Pei-Pei, Yu, Xin, Zhang, Li-Chao, Su, Ya-Nan, Wang, Zhan-You
Publicado 2022

Magnesium Ions Inhibit the Expression of Tumor Necrosis Factor α and the Activity of γ-Secretase in a β-Amyloid Protein-Dependent Mechanism in APP/PS1 Transgenic Mice

por Yu, Xin, Guan, Pei-Pei, Zhu, Di, Liang, Yun-Yue, Wang, Tao, Wang, Zhan-You, Wang, Pu
Publicado 2018

Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE(2) and PGD(2) at the earl...

por Lu, Chen-Di, Ma, Ji-Kang, Luo, Zheng-Yang, Tai, Qun-Xi, Wang, Pu, Guan, Pei-Pei
Publicado 2018

COX-2 metabolic products, the prostaglandin I(2) and F(2α), mediate the effects of TNF-α and Zn(2+) in stimulating the phosphorylation of Tau

por Wang, Yue, Guan, Pei-Pei, Yu, Xin, Guo, Yan-Su, Zhang, Ying-Jie, Wang, Zhan-You, Wang, Pu
Publicado 2017

The Role of Cyclooxygenase-2, Interleukin-1β and Fibroblast Growth Factor-2 in the Activation of Matrix Metalloproteinase-1 in Sheared-Chondrocytes and Articular Cartilage

por Guan, Pei-Pei, Guo, Jing-Wen, Yu, Xin, Wang, Yue, Wang, Tao, Konstantopoulos, Konstantinos, Wang, Zhan-You, Wang, Pu
Publicado 2015

Prostaglandin I(2) upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice

por Wang, Pu, Guan, Pei‐Pei, Guo, Jing‐Wen, Cao, Long‐Long, Xu, Guo‐Biao, Yu, Xin, Wang, Yue, Wang, Zhan‐You
Publicado 2016

By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization

por Guan, Pei-Pei, Yu, Xin, Guo, Jian-Jun, Wang, Yue, Wang, Tao, Li, Jia-Yi, Konstantopoulos, Konstantinos, Wang, Zhan-You, Wang, Pu
Publicado 2015