Function and conformation analyses of an aspartate substitution of the invariant glycine in the integrin βI domain α1-α1′ helix

por Guan, Siyu, Tan, Suet-Mien, Li, Yan, Torres, Jaume, Alex Law, S.K.
Publicado 2016

Utility of right adrenal signature veins in venous sampling for primary aldosteronism

por Shen, Zhenglin, Xu, Shaoyong, Guan, Siyu, Chen, Bo, Li, Qingan, Yu, Ming, Gao, Zhao
Publicado 2023

Proteomic sequencing analysis in a rat model of atrial fibrosis caused by chronic intermittent hypoxia

por Zhao, Bo, Wang, Hualing, Cheng, Lijun, Wang, Manman, Li, Jiao, Gu, Tianshu, Shangguan, Wenfeng, Miao, Shuai, Wang, Weiding, Liu, Xing, Guan, Siyu, Liu, Tong, Liang, Xue
Publicado 2023

Rationally targeted anti-VISTA antibody that blockades the C-C’ loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor g...

por Thakkar, Dipti, Paliwal, Shalini, Dharmadhikari, Bhushan, Guan, Siyu, Liu, Lillian, Kar, Shreya, Tulsian, Nikhil K, Gruber, Joshua J, DiMascio, Leah, Paszkiewicz, Konrad H, Ingram, Piers J, D Boyd-Kirkup, Jerome
Publicado 2022

First-in-Human Study to Evaluate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Rapidly Developed SARS-CoV-2 Therapeutic Antibody, AOD01, in Healthy Adults

por Prativadibhayankaram, Venkateshan S., Lee, Lawrence Soon-U, Lye, David, Xiaoying, Xu, Nellore, Ranjani, Pendharkar, Vishal, Hentze, Hannes, Guan, Siyu, Ayers, Benjamin J., Seah, Shirley G. K., Chye, De Hoe, Talib, Najwa S. N., Kaliaperumal, Nivashini, Ong, Wei Yee, Wong, Zi Xin, Au, Veonice B., Alok, Anshula, Connolly, John E., Boyd-Kirkup, Jerome D., Ingram, Piers J., Hanson, Brendon J., Ethirajulu, Kantharaj, O’Connell, Damian, Chan, Conrad E. Z.
Publicado 2022

The Fc-mediated effector functions of a potent SARS-CoV-2 neutralizing antibody, SC31, isolated from an early convalescent COVID-19 patient, are essential for the optimal therapeut...

por Chan, Conrad E. Z., Seah, Shirley G. K., Chye, De Hoe, Massey, Shane, Torres, Maricela, Lim, Angeline P. C., Wong, Steven K. K., Neo, Jacklyn J. Y., Wong, Pui San, Lim, Jie Hui, Loh, Gary S. L., Wang, Dongling, Boyd-Kirkup, Jerome D., Guan, Siyu, Thakkar, Dipti, Teo, Guo Hui, Purushotorman, Kiren, Hutchinson, Paul E., Young, Barnaby E., Low, Jenny G., MacAry, Paul A., Hentze, Hannes, Prativadibhayankara, Venkateshan S., Ethirajulu, Kantharaj, Comer, Jason E., Tseng, Chien-Te K., Barrett, Alan D. T., Ingram, Piers J., Brasel, Trevor, Hanson, Brendon John
Publicado 2021