Cross-Talk between AURKA and Plk1 in Mitotic Entry and Spindle Assembly

por Asteriti, Italia Anna, De Mattia, Fabiola, Guarguaglini, Giulia
Publicado 2015

Phosphorylation, Mg-ADP, and Inhibitors Differentially Shape the Conformational Dynamics of the A-Loop of Aurora-A

por Musavizadeh, Zahra, Grottesi, Alessandro, Guarguaglini, Giulia, Paiardini, Alessandro
Publicado 2021

Aurora-A inactivation causes mitotic spindle pole fragmentation by unbalancing microtubule-generated forces

por Asteriti, Italia A, Giubettini, Maria, Lavia, Patrizia, Guarguaglini, Giulia
Publicado 2011

When Just One Phosphate Is One Too Many: The Multifaceted Interplay between Myc and Kinases

por Boi, Dalila, Rubini, Elisabetta, Breccia, Sara, Guarguaglini, Giulia, Paiardini, Alessandro
Publicado 2023

Revisiting the “satisfaction of spatial restraints” approach of MODELLER for protein homology modeling

por Janson, Giacomo, Grottesi, Alessandro, Pietrosanto, Marco, Ausiello, Gabriele, Guarguaglini, Giulia, Paiardini, Alessandro
Publicado 2019

Actin-dependent regulation of cilia length by the inverted formin FHDC1

por Copeland, Sarah J., McRae, Andrea, Guarguaglini, Giulia, Trinkle-Mulcahy, Laura, Copeland, John W.
Publicado 2018

Identification of small molecule inhibitors of the Aurora-A/TPX2 complex

por Asteriti, Italia Anna, Daidone, Frederick, Colotti, Gianni, Rinaldo, Serena, Lavia, Patrizia, Guarguaglini, Giulia, Paiardini, Alessandro
Publicado 2017

AURKA destruction is decoupled from its activity at mitotic exit but is essential to suppress interphase activity

por Abdelbaki, Ahmed, Akman, H. Begum, Poteau, Marion, Grant, Rhys, Gavet, Olivier, Guarguaglini, Giulia, Lindon, Catherine
Publicado 2020

Nuclear localisation of Aurora-A: its regulation and significance for Aurora-A functions in cancer

por Naso, Francesco Davide, Boi, Dalila, Ascanelli, Camilla, Pamfil, Georgiana, Lindon, Catherine, Paiardini, Alessandro, Guarguaglini, Giulia
Publicado 2021

The Aurora-A inhibitor MLN8237 affects multiple mitotic processes and induces dose-dependent mitotic abnormalities and aneuploidy

por Asteriti, Italia Anna, Cesare, Erica Di, Mattia, Fabiola De, Hilsenstein, Volker, Neumann, Beate, Cundari, Enrico, Lavia, Patrizia, Guarguaglini, Giulia
Publicado 2014

Visualization of human karyopherin beta-1/importin beta-1 interactions with protein partners in mitotic cells by co-immunoprecipitation and proximity ligation assays

por Di Francesco, Laura, Verrico, Annalisa, Asteriti, Italia Anna, Rovella, Paola, Cirigliano, Pietro, Guarguaglini, Giulia, Schininà, Maria Eugenia, Lavia, Patrizia
Publicado 2018

ALFI: Cell cycle phenotype annotations of label-free time-lapse imaging data from cultured human cells

por Antonelli, Laura, Polverino, Federica, Albu, Alexandra, Hada, Aroj, Asteriti, Italia A., Degrassi, Francesca, Guarguaglini, Giulia, Maddalena, Lucia, Guarracino, Mario R.
Publicado 2023

Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit

por Naso, Francesco D., Sterbini, Valentina, Crecca, Elena, Asteriti, Italia A., Russo, Alessandra D., Giubettini, Maria, Cundari, Enrico, Lindon, Catherine, Rosa, Alessandro, Guarguaglini, Giulia
Publicado 2020

AurkA nuclear localization is promoted by TPX2 and counteracted by protein degradation

por Asteriti, Italia Anna, Polverino, Federica, Stagni, Venturina, Sterbini, Valentina, Ascanelli, Camilla, Naso, Francesco Davide, Mastrangelo, Anna, Rosa, Alessandro, Paiardini, Alessandro, Lindon, Catherine, Guarguaglini, Giulia
Publicado 2023

TGFbeta Induces Binucleation/Polyploidization in Hepatocytes through a Src-Dependent Cytokinesis Failure

por De Santis Puzzonia, Marco, Cozzolino, Angela Maria, Grassi, Germana, Bisceglia, Francesca, Strippoli, Raffaele, Guarguaglini, Giulia, Citarella, Franca, Sacchetti, Benedetto, Tripodi, Marco, Marchetti, Alessandra, Amicone, Laura
Publicado 2016

M2 Muscarinic Receptor Activation Impairs Mitotic Progression and Bipolar Mitotic Spindle Formation in Human Glioblastoma Cell Lines

por Di Bari, Maria, Tombolillo, Vanessa, Alessandrini, Francesco, Guerriero, Claudia, Fiore, Mario, Asteriti, Italia Anna, Castigli, Emilia, Sciaccaluga, Miriam, Guarguaglini, Giulia, Degrassi, Francesca, Tata, Ada Maria
Publicado 2021

X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics

por Licursi, Valerio, Anzellotti, Silvia, Favaro, Jessica, Sineri, Serena, Carucci, Nicoletta, Cundari, Enrico, Fiore, Mario, Guarguaglini, Giulia, Pippa, Simone, Nisi, Paola S., Vernì, Fiammetta, Biagioni, Stefano, Cacci, Emanuele, Amendola, Roberto, Lupo, Giuseppe, Negri, Rodolfo
Publicado 2020

Revisiting degron motifs in human AURKA required for its targeting by APC/C(FZR1)

por Abdelbaki, Ahmed, Ascanelli, Camilla, Okoye, Cynthia N, Akman, H Begum, Janson, Giacomo, Min, Mingwei, Marcozzi, Chiara, Hagting, Anja, Grant, Rhys, De Luca, Maria, Asteriti, Italia Anna, Guarguaglini, Giulia, Paiardini, Alessandro, Lindon, Catherine
Publicado 2022

PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc

por Boi, Dalila, Souvalidou, Fani, Capelli, Davide, Polverino, Federica, Marini, Grazia, Montanari, Roberta, Pochetti, Giorgio, Tramonti, Angela, Contestabile, Roberto, Trisciuoglio, Daniela, Carpinelli, Patrizia, Ascanelli, Camilla, Lindon, Catherine, De Leo, Alessandro, Saviano, Michele, Di Santo, Roberto, Costi, Roberta, Guarguaglini, Giulia, Paiardini, Alessandro
Publicado 2021

AMBRA1 phosphorylation by CDK1 and PLK1 regulates mitotic spindle orientation

por Faienza, Fiorella, Polverino, Federica, Rajendraprasad, Girish, Milletti, Giacomo, Hu, Zehan, Colella, Barbara, Gargano, Deborah, Strappazzon, Flavie, Rizza, Salvatore, Vistesen, Mette Vixø, Luo, Yonglun, Antonioli, Manuela, Cianfanelli, Valentina, Ferraina, Caterina, Fimia, Gian Maria, Filomeni, Giuseppe, De Zio, Daniela, Dengjel, Joern, Barisic, Marin, Guarguaglini, Giulia, Di Bartolomeo, Sabrina, Cecconi, Francesco
Publicado 2023