Quantitative glycoproteomics reveals cellular substrate selectivity of the ER protein quality control sensors UGGT1 and UGGT2

por Adams, Benjamin M, Canniff, Nathan P, Guay, Kevin P, Larsen, Ida Signe Bohse, Hebert, Daniel N
Publicado 2020

Secretion of functional α1-antitrypsin is cell type dependent: Implications for intramuscular delivery for gene therapy

por Ke, Haiping, Guay, Kevin P., Flotte, Terence R., Gierasch, Lila M., Gershenson, Anne, Hebert, Daniel N.
Publicado 2022

Rescue of secretion of a rare-disease associated mis-folded mutant glycoprotein in UGGT1 knock-out mammalian cells

por Tax, Gábor, Guay, Kevin P., Soldà, Tatiana, Hitchman, Charlie J., Hill, Johan C., Vasiljević, Snežana, Lia, Andrea, Modenutti, Carlos P., Straatman, Kees R., Santino, Angelo, Molinari, Maurizio, Zitzmann, Nicole, Hebert, Daniel N., Roversi, Pietro, Trerotola, Marco
Publicado 2023

A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint

por Guay, Kevin P., Ibba, Roberta, Kiappes, J.L., Vasiljević, Snežana, Bonì, Francesco, De Benedictis, Maria, Zeni, Ilaria, Le Cornu, James D., Hensen, Mario, Chandran, Anu V., Kantsadi, Anastassia L., Caputo, Alessandro T., Blanco Capurro, Juan I., Bayo, Yusupha, Hill, Johan C., Hudson, Kieran, Lia, Andrea, Brun, Juliane, Withers, Stephen G., Martí, Marcelo, Biasini, Emiliano, Santino, Angelo, De Rosa, Matteo, Milani, Mario, Modenutti, Carlos P., Hebert, Daniel N., Zitzmann, Nicole, Roversi, Pietro
Publicado 2023