Low-Molecular-Weight NGF Mimetic Corrects the Cognitive Deficit and Depression-like Behavior in Experimental Diabetes

por Ostrovskaya, R. U., Yagubova, S. S., Gudasheva, T. A., Seredenin, S. B.
Publicado 2017

Antidepressant Effect of an Orally Administered Dipeptide Mimetic of the Brain-Derived Neurotrophic Factor

por Povarnina, P. Y., Garibova, T. L., Gudasheva, T. A., Seredenin, S. B.
Publicado 2018

Novel Technologies for Dipeptide Drugs Design and their Implantation

por Gudasheva, Tatiana A., Ostrovskaya, Rita U., Seredenin, Sergey B.
Publicado 2018

A Novel Dipeptide NGF Mimetic GK-2 Selectively Activating the PI3K/AKT Signaling Pathway Promotes the Survival of Pancreatic β-Cells in a Rat Model of Diabetes

por Ostrovskaya, R. U., Ivanov, S. V., Gudasheva, T. A., Seredenin, S. B.
Publicado 2019

The Novel Dipeptide Translocator Protein Ligand, Referred to As GD-23, Exerts Anxiolytic and Nootropic Activities

por Povarnina, P. Yu., Yarkov, S. A., Gudasheva, T. A., Yarkova, M. A., Seredenin, S. B.
Publicado 2015

Dimeric mimetic of BDNF loop 4 promotes survival of serum-deprived cell through TrkB-dependent apoptosis suppression

por Zainullina, L. F., Vakhitova, Yu. V., Lusta, A. Yu., Gudasheva, T. A., Seredenin, S. B.
Publicado 2021

Mimetics of brain-derived neurotrophic factor loops 1 and 4 are active in a model of ischemic stroke in rats

por Gudasheva, Tatyana A, Povarnina, Polina, Logvinov, Ilya O, Antipova, Tatyana A, Seredenin, Sergey B
Publicado 2016

A Nerve Growth Factor Dipeptide Mimetic Stimulates Neurogenesis and Synaptogenesis in the Hippocampus and Striatum of Adult Rats with Focal Cerebral Ischemia

por Gudasheva, T. A., Povarnina, P. Yu., Volkova, A. A., Kruglov, S. V., Antipova, T. A., Seredenin, S. B.
Publicado 2019

Original Nerve Growth Factor Mimetic Dipeptide GK-2 Restores Impaired Cognitive Functions in Rat Models of Alzheimer’s Disease

por Povarnina, P.Yu., Vorontsova, O.N., Gudasheva, T.A., Ostrovskaya, R.U., Seredenin, S.B.
Publicado 2013

A Low-Molecular-Weight BDNF Mimetic, Dipeptide GSB-214, Prevents Memory Impairment in Rat Models of Alzheimer’s Disease

por Povarnina, P. Yu., Volkova, A. A., Vorontsova, O. N., Kamensky, A. A., Gudasheva, T. A., Seredenin, S. B.
Publicado 2022

Dimeric dipeptide mimetics of the nerve growth factor Loop 4 and Loop 1 activate TRKA with different patterns of intracellular signal transduction

por Gudasheva, Tatyana A., Povarnina, Polina Yu, Antipova, Tatyana A., Firsova, Yulia N., Konstantinopolsky, Mark A., Seredenin, Sergey B.
Publicado 2015

The New Dipeptide TSPO Ligands: Design, Synthesis and Structure–Anxiolytic Activity Relationship †

por Gudasheva, Tatiana A., Deeva, Olga A., Pantileev, Andrey S., Mokrov, Grigory V., Rybina, Inna V., Yarkova, Milada A., Seredenin, Sergei B.
Publicado 2020

Antidepressant-like Effects of BDNF and NGF Individual Loop Dipeptide Mimetics Depend on the Signal Transmission Patterns Associated with Trk

por Mezhlumyan, Armen G., Tallerova, Anna V., Povarnina, Polina Y., Tarasiuk, Aleksey V., Sazonova, Nellya M., Gudasheva, Tatiana A., Seredenin, Sergey B.
Publicado 2022

Antidepressant Effect of Dimeric Dipeptide GSB-106, an Original Low-Molecular-Weight Mimetic of BDNF

por Seredenin, S.B., Voronina, T.A., Gudasheva, T.A., Garibova, T.L., Molodavkin, G.M., Litvinova, S.A., Elizarova, E.A., Poseva, V.I.
Publicado 2013

Neuroprotective effect of novel cognitive enhancer noopept on AD-related cellular model involves the attenuation of apoptosis and tau hyperphosphorylation

por Ostrovskaya, Rita U, Vakhitova, Yulia V, Kuzmina, Uliyana Sh, Salimgareeva, Milyausha Kh, Zainullina, Liana F, Gudasheva, Tatiana A, Vakhitov, Vener A, Seredenin, Sergey B
Publicado 2014

Low-Molecular Weight BDNF Mimetic, Dimeric Dipeptide GSB-106, Reverses Depressive Symptoms in Mouse Chronic Social Defeat Stress

por Gudasheva, Tatiana A., Tallerova, Anna V., Mezhlumyan, Armen G., Antipova, Tatyana A., Logvinov, Ilya O., Firsova, Yulia N., Povarnina, Polina Y., Seredenin, Sergey B.
Publicado 2021

Analysis of Antidepressant-like Effects and Action Mechanisms of GSB-106, a Small Molecule, Affecting the TrkB Signaling

por Vakhitova, Yulia V., Kalinina, Tatiana S., Zainullina, Liana F., Lusta, Anastasiya Yu., Volkova, Anna V., Kudryashov, Nikita V., Gudasheva, Tatiana A., Shimshirt, Alexander A., Kadnikov, Ilya A., Voronin, Mikhail V., Seredenin, Sergei B.
Publicado 2021