The 2.0 Å X-ray structure for yeast acetohydroxyacid synthase provides new insights into its cofactor and quaternary structure requirements

por Lonhienne, Thierry, Garcia, Mario D., Fraser, James A., Williams, Craig M., Guddat, Luke W.
Publicado 2017

Crystal structures and inhibition of Trypanosoma brucei hypoxanthine–guanine phosphoribosyltransferase

por Terán, David, Hocková, Dana, Česnek, Michal, Zíková, Alena, Naesens, Lieve, Keough, Dianne T., Guddat, Luke W.
Publicado 2016

Processivity and enzymatic mechanism of a multifunctional family 5 endoglucanase from Bacillus subtilis BS-5 with potential applications in the saccharification of cellulosic subst...

por Wu, Bin, Zheng, Shan, Pedroso, Marcelo Monteiro, Guddat, Luke W., Chang, Siyuan, He, Bingfang, Schenk, Gerhard
Publicado 2018

Relative catalytic efficiencies and transcript levels of three d‐ and two l‐lactate dehydrogenases for optically pure d‐lactate production in Sporolactobacillus inulinus

por Wu, Bin, Yu, Qi, Zheng, Shan, Pedroso, Marcelo Monteiro, Guddat, Luke W., He, Bingfang, Schenk, Gerhard
Publicado 2018

Conformational Changes in a Macrolide Antibiotic Binding Protein From Mycobacterium smegmatis Upon ADP Binding

por Zhang, Qingqing, Liu, Xiang, Liu, Huijuan, Zhang, Bingjie, Yang, Haitao, Mi, Kaixia, Guddat, Luke W., Rao, Zihe
Publicado 2021

Crystal structures of a purple acid phosphatase, representing different steps of this enzyme's catalytic cycle

por Schenk, Gerhard, Elliott, Tristan W, Leung, Eleanor, Carrington, Lyle E, Mitić, Nataša, Gahan, Lawrence R, Guddat, Luke W
Publicado 2008

Structural basis of trehalose recycling by the ABC transporter LpqY-SugABC

por Liu, Fengjiang, Liang, Jingxi, Zhang, Bing, Gao, Yan, Yang, Xiuna, Hu, Tianyu, Yang, Haitao, Xu, Wenqing, Guddat, Luke W., Rao, Zihe
Publicado 2020

Structural basis of resistance to herbicides that target acetohydroxyacid synthase

por Lonhienne, Thierry, Cheng, Yan, Garcia, Mario D., Hu, Shu Hong, Low, Yu Shang, Schenk, Gerhard, Williams, Craig M., Guddat, Luke W.
Publicado 2022

The structure of Human Microplasmin in Complex with Textilinin-1, an Aprotinin-like Inhibitor from the Australian Brown Snake

por Millers, Emma-Karin I., Johnson, Lambro A., Birrell, Geoff W., Masci, Paul P., Lavin, Martin F., de Jersey, John, Guddat, Luke W.
Publicado 2013

Discovery of the first macrolide antibiotic binding protein in Mycobacterium tuberculosis: a new antibiotic resistance drug target

por Zhang, Qingqing, Liu, Huijuan, Liu, Xiang, Jiang, Dunquan, Zhang, Bingjie, Tian, Hongliang, Yang, Cheng, Guddat, Luke W., Yang, Haitao, Mi, Kaixia, Rao, Zihe
Publicado 2018

Structural insights into substrate recognition by the type VII secretion system

por Wang, Shuhui, Zhou, Kaixuan, Yang, Xiaolin, Zhang, Bing, Zhao, Yao, Xiao, Yu, Yang, Xiuna, Yang, Haitao, Guddat, Luke W., Li, Jun, Rao, Zihe
Publicado 2019

Broad spectrum antibiotic-degrading metallo-β-lactamases are phylogenetically diverse

por Pedroso, Marcelo Monteiro, Waite, David W., Melse, Okke, Wilson, Liam, Mitić, Nataša, McGeary, Ross P., Antes, Iris, Guddat, Luke W., Hugenholtz, Philip, Schenk, Gerhard
Publicado 2020

Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases?

por Hadler, Kieran S, Huber, Thomas, Cassady, A Ian, Weber, Jane, Robinson, Jodie, Burrows, Allan, Kelly, Gregory, Guddat, Luke W, Hume, David A, Schenk, Gerhard, Flanagan, Jack U
Publicado 2008

Molecular recognition of trehalose and trehalose analogues by Mycobacterium tuberculosis LpqY-SugABC

por Liang, Jingxi, Liu, Fengjiang, Xu, Peng, Shangguan, Wei, Hu, Tianyu, Wang, Shule, Yang, Xiaolin, Xiong, Zhiqi, Yang, Xiuna, Guddat, Luke W., Yu, Biao, Rao, Zihe, Zhang, Bing
Publicado 2023

Mycobacterial dynamin-like protein IniA mediates membrane fission

por Wang, Manfu, Guo, Xiangyang, Yang, Xiuna, Zhang, Bing, Ren, Jie, Liu, Aijun, Ran, Yajun, Yan, Bing, Chen, Fang, Guddat, Luke W., Hu, Junjie, Li, Jun, Rao, Zihe
Publicado 2019

Cryo-EM structure of mycobacterial cytochrome bd reveals two oxygen access channels

por Wang, Weiwei, Gao, Yan, Tang, Yanting, Zhou, Xiaoting, Lai, Yuezheng, Zhou, Shan, Zhang, Yuying, Yang, Xiuna, Liu, Fengjiang, Guddat, Luke W., Wang, Quan, Rao, Zihe, Gong, Hongri
Publicado 2021

Structural and Functional Insight into the Mechanism of the Fe−S Cluster‐Dependent Dehydratase from Paralcaligenes ureilyticus

por Bayaraa, Tenuun, Lonhienne, Thierry, Sutiono, Samuel, Melse, Okke, Brück, Thomas B., Marcellin, Esteban, Bernhardt, Paul V., Boden, Mikael, Harmer, Jeffrey R., Sieber, Volker, Guddat, Luke W., Schenk, Gerhard
Publicado 2022

Structure and mechanism of potent bifunctional β-lactam- and homoserine lactone-degrading enzymes from marine microorganisms

por Selleck, Christopher, Pedroso, Marcelo Monteiro, Wilson, Liam, Krco, Stefan, Knaven, Esmée Gianna, Miraula, Manfredi, Mitić, Nataša, Larrabee, James A., Brück, Thomas, Clark, Alice, Guddat, Luke W., Schenk, Gerhard
Publicado 2020

Cryo-EM structures for the Mycobacterium tuberculosis iron-loaded siderophore transporter IrtAB

por Sun, Shan, Gao, Yan, Yang, Xiaolin, Yang, Xiuna, Hu, Tianyu, Liang, Jingxi, Xiong, Zhiqi, Ran, Yuting, Ren, Pengxuan, Bai, Fang, Guddat, Luke W, Yang, Haitao, Rao, Zihe, Zhang, Bing
Publicado 2022

Genome-Guided Analysis of Seven Weed Species Reveals Conserved Sequence and Structural Features of Key Gene Targets for Herbicide Development

por Shah, Sarah, Lonhienne, Thierry, Murray, Cody-Ellen, Chen, Yibi, Dougan, Katherine E., Low, Yu Shang, Williams, Craig M., Schenk, Gerhard, Walter, Gimme H., Guddat, Luke W., Chan, Cheong Xin
Publicado 2022