AGING TREATMENT BY COUNTERACTING INTRINSIC DNA DAMAGE AND IMMUNOSENESCENCE

por Gudkov, Andrei
Publicado 2019

Pretreatment of the Cells With Brefeldin A and Cycloheximide Differently Regulates Fas and TNF Stimulated Apoptosis

por Neznanov, Nickolay, Gudkov, Andrei
Publicado 2001

ATM is activated in blood monocytes after tumor radiation

por Gudkov, Andrei V., Komarova, Elena A.
Publicado 2013

Elimination of Proliferating Cells Unmasks the Shift from Senescence to Quiescence Caused by Rapamycin

por Leontieva, Olga V., Demidenko, Zoya N., Gudkov, Andrei V., Blagosklonny, Mikhail V.
Publicado 2011

Proteotoxic stress targeted therapy (PSTT): induction of protein misfolding enhances the antitumor effect of the proteasome inhibitor bortezomib

por Neznanov, Nickolay, Komarov, Andrei P., Neznanova, Lubov, Stanhope-Baker, Patricia, Gudkov, Andrei V.
Publicado 2011

Structural dissection of sequence recognition and catalytic mechanism of human LINE-1 endonuclease

por Miller, Ian, Totrov, Max, Korotchkina, Lioubov, Kazyulkin, Denis N, Gudkov, Andrei V, Korolev, Sergey
Publicado 2021

Assessment of Sex, Age, and Metabolism Relationships to Serum Thyroid Concentrations in Retired Alaskan Husky Sled Dogs

por Lenfest, Margret, Loftus, John P., Huson, Heather J., Gudkov, Andrei, Andrianova, Katerina, Fleyshman, Daria, Wakshlag, Joseph
Publicado 2022

Longitudinal analysis of blood markers reveals progressive loss of resilience and predicts human lifespan limit

por Pyrkov, Timothy V., Avchaciov, Konstantin, Tarkhov, Andrei E., Menshikov, Leonid I., Gudkov, Andrei V., Fedichev, Peter O.
Publicado 2021

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

por Korotchkina, Lioubov G., Leontieva, Olga V., Bukreeva, Elena I., Demidenko, Zoya N., Gudkov, Andrei V., Blagosklonny, Mikhail V.
Publicado 2010

Different Effect of Proteasome Inhibition on Vesicular Stomatitis Virus and Poliovirus Replication

por Neznanov, Nickolay, Dragunsky, Eugenia M., Chumakov, Konstantin M., Neznanova, Lubov, Wek, Ronald C., Gudkov, Andrei V., Banerjee, Amiya K.
Publicado 2008

2178 Drug development core facilitates institutional collaboration and translational science innovation

por Morse, Gene, Puzanov, Igor, Gudkov, Andrei, DiFrancesco, Robin, Jusko, William, Ernstoff, Marc, Mohler, James, Murphy, Timothy, Bies, Robert
Publicado 2018

A Flagellin-Derived Toll-Like Receptor 5 Agonist Stimulates Cytotoxic Lymphocyte-Mediated Tumor Immunity

por Leigh, Nicholas D., Bian, Guanglin, Ding, Xilai, Liu, Hong, Aygun-Sunar, Semra, Burdelya, Lyudmila G., Gudkov, Andrei V., Cao, Xuefang
Publicado 2014

New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53(−/−) mice by delaying carcinogenesis

por Comas, Maria, Toshkov, Ilia, Kuropatwinski, Karen K., Chernova, Olga B., Polinsky, Alexander, Blagosklonny, Mikhail V., Gudkov, Andrei V., Antoch, Marina P.
Publicado 2012

Quantitative characterization of biological age and frailty based on locomotor activity records

por Pyrkov, Timothy V., Getmantsev, Evgeny, Zhurov, Boris, Avchaciov, Konstantin, Pyatnitskiy, Mikhail, Menshikov, Leonid, Khodova, Kristina, Gudkov, Andrei V., Fedichev, Peter O.
Publicado 2018

First-in-human study of anticancer immunotherapy drug candidate mobilan: safety, pharmacokinetics and pharmacodynamics in prostate cancer patients

por Eremina, Natalia V., Kazey, Vasily I., Mishugin, Sergey V., Leonenkov, Roman V., Pushkar, Dmitry Y., Mett, Vadim L., Gudkov, Andrei V.
Publicado 2020

Unsupervised learning of aging principles from longitudinal data

por Avchaciov, Konstantin, Antoch, Marina P., Andrianova, Ekaterina L., Tarkhov, Andrei E., Menshikov, Leonid I., Burmistrova, Olga, Gudkov, Andrei V., Fedichev, Peter O.
Publicado 2022

Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice

por Komarova, Elena A., Antoch, Marina P., Novototskaya, Liliya R., Chernova, Olga B., Paszkiewicz, Geraldine, Leontieva, Olga V., Blagosklonny, Mikhail V., Gudkov, Andrei V.
Publicado 2012

Development of infrastructure for a systemic multidisciplinary approach to study aging in retired sled dogs

por Fleyshman, Daria I., Wakshlag, Joseph J., Huson, Heather J., Loftus, John P., Olby, Natasha J., Brodsky, Leonid, Gudkov, Andrei V., Andrianova, Ekaterina L.
Publicado 2021

Targeted Modulation of Interferon Response-Related Genes with IFN-Alpha/Lambda Inhibition

por Sur, Debpali, Leonova, Katerina, Levi, Bar, Markowitz, Shany Ivon, Cohen-Harazi, Raichel, Gitlin, Ilya, Gurova, Katerina, Gudkov, Andrei, Pinhasov, Albert, Koman, Igor, Nesher, Elimelech
Publicado 2022

Toll-like receptor-5 agonist Entolimod broadens the therapeutic window of 5-fluorouracil by reducing its toxicity to normal tissues in mice

por Kojouharov, Bojidar M., Brackett, Craig M., Veith, Jean M., Johnson, Christopher P., Gitlin, Ilya I., Toshkov, Ilia A., Gleiberman, Anatoli S., Gudkov, Andrei V., Burdelya, Lyudmila G.
Publicado 2014