A history of the roles of cytochrome P450 enzymes in the toxicity of drugs

por Guengerich, F. Peter
Publicado 2020

Inhibition of Cytochrome P450 Enzymes by Drugs—Molecular Basis and Practical Applications

por Guengerich, F. Peter
Publicado 2022

Survey of Human Oxidoreductases and Cytochrome P450 Enzymes Involved in the Metabolism of Xenobiotic and Natural Chemicals

por Rendic, Slobodan, Guengerich, F. Peter
Publicado 2014

Mechanism of the Third Oxidative Step in the Conversion of Androgens to Estrogens by Cytochrome P450 19A1 Steroid Aromatase

por Yoshimoto, Francis K., Guengerich, F. Peter
Publicado 2014

Etheno adducts: from tRNA modifications to DNA adducts and back to miscoding ribonucleotides

por Guengerich, F. Peter, Ghodke, Pratibha P.
Publicado 2021

DNA polymerases η and κ bypass N(2)-guanine-O(6)-alkylguanine DNA alkyltransferase cross-linked DNA-peptides

por Ghodke, Pratibha P., Guengerich, F. Peter
Publicado 2021

Cellular retinoid-binding proteins transfer retinoids to human cytochrome P450 27C1 for desaturation

por Glass, Sarah M., Guengerich, F. Peter
Publicado 2021

Mechanistic Studies with DNA Polymerases Reveal Complex Outcomes following Bypass of DNA Damage

por Eoff, Robert L., Choi, Jeong-Yun, Guengerich, F. Peter
Publicado 2010

Roles of selected non-P450 human oxidoreductase enzymes in protective and toxic effects of chemicals: review and compilation of reactions

por Rendić, Slobodan P., Crouch, Rachel D., Guengerich, F. Peter
Publicado 2022

Kinetics of cytochrome P450 3A4 inhibition by heterocyclic drugs defines a general sequential multistep binding process

por Guengerich, F. Peter, McCarty, Kevin D., Chapman, Jesse G.
Publicado 2020

Minipig cytochrome P450 3A, 2A and 2C enzymes have similar properties to human analogs

por Soucek, Pavel, Zuber, Roman, Anzenbacherová, Eva, Anzenbacher, Pavel, Guengerich, F Peter
Publicado 2001

Tight binding of cytochrome b(5) to cytochrome P450 17A1 is a critical feature of stimulation of C21 steroid lyase activity and androgen synthesis

por Kim, Donghak, Kim, Vitchan, McCarty, Kevin D., Guengerich, F. Peter
Publicado 2021

Stepwise binding of inhibitors to human cytochrome P450 17A1 and rapid kinetics of inhibition of androgen biosynthesis

por Guengerich, F. Peter, McCarty, Kevin D., Chapman, Jesse G., Tateishi, Yasuhiro
Publicado 2021

Working toward reducing bias in peer review

por Rye, Kerry-Anne, Davidson, Nicholas O., Burlingame, Alma L., Guengerich, F. Peter
Publicado 2021

Working toward reducing bias in peer review

por Rye, Kerry-Anne, Davidson, Nicholas O., Burlingame, Alma L., Guengerich, F. Peter
Publicado 2021

Working Toward Reducing Bias in Peer Review

por Rye, Kerry-Anne, Davidson, Nicholas O., Burlingame, Alma L., Guengerich, F. Peter
Publicado 2021

In Vitro Activation of Cytochrome P450 46A1 (CYP46A1) by Efavirenz-Related Compounds

por Mast, Natalia, Verwilst, Peter, Wilkey, Clayton J., Guengerich, F. Peter, Pikuleva, Irina A.
Publicado 2019

Structure of the 1,N(2)-Ethenodeoxyguanosine Adduct Opposite Cytosine in Duplex DNA: Hoogsteen Base Pairing at pH 5.2

por Shanmugam, Ganesh, Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.
Publicado 2008

Structure of the 1,N(2)-Etheno-2′-deoxyguanosine Lesion in the 3′-G(εdG)T-5′ Sequence Opposite a One-Base Deletion

por Shanmugam, Ganesh, Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.
Publicado 2010

1,N(2)-Etheno-2′-deoxyguanosine Adopts the syn Conformation about the Glycosyl Bond When Mismatched with Deoxyadenosine

por Shanmugam, Ganesh, Kozekov, Ivan D., Guengerich, F. Peter, Rizzo, Carmelo J., Stone, Michael P.
Publicado 2011