Macrophage Biology and Mechanisms of Immune Suppression in Breast Cancer

por Mehta, Anita K., Kadel, Sapana, Townsend, Madeline G., Oliwa, Madisson, Guerriero, Jennifer L.
Publicado 2021

STING agonism enhances anti-tumor immune responses and therapeutic efficacy of PARP inhibition in BRCA-associated breast cancer

por Pantelidou, Constantia, Jadhav, Heta, Kothari, Aditi, Liu, Renyan, Wulf, Gerburg M., Guerriero, Jennifer L., Shapiro, Geoffrey I.
Publicado 2022

Elevated Expression of Squamous Cell Carcinoma Antigen (SCCA) Is Associated with Human Breast Carcinoma

por Catanzaro, Joseph M., Guerriero, Jennifer L., Liu, Jingxuan, Ullman, Erica, Sheshadri, Namratha, Chen, John J., Zong, Wei-Xing
Publicado 2011

Combination therapy targeting both innate and adaptive immunity improves survival in a pre-clinical model of ovarian cancer

por Hartl, Christina A., Bertschi, Adrian, Puerto, Regina Bou, Andresen, Carolin, Cheney, Emily M., Mittendorf, Elizabeth A., Guerriero, Jennifer L., Goldberg, Michael S.
Publicado 2019

The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

por Dou, Zhixun, Chattopadhyay, Mohar, Pan, Ji-An, Guerriero, Jennifer L., Jiang, Ya-Ping, Ballou, Lisa M., Yue, Zhenyu, Lin, Richard Z., Zong, Wei-Xing
Publicado 2010

BH3-profiling identifies heterogeneous dependency on Bcl-2 family members in Multiple Myeloma and predicts sensitivity to BH3 mimetics

por Touzeau, Cyrille, Ryan, Jeremy, Guerriero, Jennifer L., Moreau, Philippe, Chonghaile, Triona Ni, Gouill, Steven Le, Richardson, Paul, Anderson, Kenneth, Amiot, Martine, Letai, Anthony
Publicado 2015

Comparing syngeneic and autochthonous models of breast cancer to identify tumor immune components that correlate with response to immunotherapy in breast cancer

por Lal, Jessica Castrillon, Townsend, Madeline G., Mehta, Anita K., Oliwa, Madisson, Miller, Eric, Sotayo, Alaba, Cheney, Emily, Mittendorf, Elizabeth A., Letai, Anthony, Guerriero, Jennifer L.
Publicado 2021

Quality Control for Single Cell Analysis of High-plex Tissue Profiles using CyLinter

por Baker, Gregory J., Novikov, Edward, Zhao, Ziyuan, Vallius, Tuulia, Davis, Janae A., Lin, Jia-Ren, Muhlich, Jeremy L., Mittendorf, Elizabeth A., Santagata, Sandro, Guerriero, Jennifer L., Sorger, Peter K.
Publicado 2023

The Immunology of Hormone Receptor Positive Breast Cancer

por Goldberg, Jonathan, Pastorello, Ricardo G., Vallius, Tuulia, Davis, Janae, Cui, Yvonne Xiaoyong, Agudo, Judith, Waks, Adrienne G., Keenan, Tanya, McAllister, Sandra S., Tolaney, Sara M., Mittendorf, Elizabeth A., Guerriero, Jennifer L.
Publicado 2021

Early on-treatment transcriptional profiling as a tool for improving pathological response prediction in HER2-positive inflammatory breast cancer

por Pernas, Sonia, Guerriero, Jennifer L., Naumenko, Sergey, Goel, Shom, Regan, Meredith M., Hu, Jiani, Harrison, Beth T., Lynce, Filipa, Lin, Nancy U., Partridge, Ann, Morikawa, Aki, Hutchinson, John, Mittendorf, Elizabeth A., Sokolov, Artem, Overmoyer, Beth
Publicado 2022

Leveraging immune resistance archetypes in solid cancer to inform next-generation anticancer therapies

por Anderson, Kristin G, Braun, David A, Buqué, Aitziber, Gitto, Sarah B, Guerriero, Jennifer L, Horton, Brendan, Keenan, Bridget P, Kim, Teresa S, Overacre-Delgoffe, Abigail, Ruella, Marco, Triplett, Todd A, Veeranki, Omkara, Verma, Vivek, Zhang, Fan
Publicado 2023

Aging-Associated Alterations in Mammary Epithelia and Stroma Revealed by Single-Cell RNA Sequencing

por Li, Carman Man-Chung, Shapiro, Hana, Tsiobikas, Christina, Selfors, Laura M., Chen, Huidong, Rosenbluth, Jennifer, Moore, Kaitlin, Gupta, Kushali P., Kenneth Gray, G., Oren, Yaara, Steinbaugh, Michael J., Guerriero, Jennifer L., Pinello, Luca, Regev, Aviv, Brugge, Joan S.
Publicado 2020

Polymerase θ inhibition activates the cGAS-STING pathway and cooperates with immune checkpoint blockade in models of BRCA-deficient cancer

por Patterson-Fortin, Jeffrey, Jadhav, Heta, Pantelidou, Constantia, Phan, Tin, Grochala, Carter, Mehta, Anita K., Guerriero, Jennifer L., Wulf, Gerburg M., Wolpin, Brian M., Stanger, Ben Z., Aguirre, Andrew J., Cleary, James M., D’Andrea, Alan D., Shapiro, Geoffrey I.
Publicado 2023

Combination Therapies to Improve the Efficacy of Immunotherapy in Triple-negative Breast Cancer

por Alečković, Maša, Li, Zheqi, Zhou, Ningxuan, Qiu, Xintao, Lulseged, Bethlehem, Foidart, Pierre, Huang, Xiao-Yun, Garza, Kodie, Shu, Shaokun, Kesten, Nikolas, Li, Rong, Lim, Klothilda, Garrido-Castro, Ana C., Guerriero, Jennifer L., Qi, Jun, Long, Henry W., Polyak, Kornelia
Publicado 2023

Programs, Origins, and Niches of Immunomodulatory Myeloid Cells in Gliomas

por Miller, Tyler E., El Farran, Chadi A., Couturier, Charles P., Chen, Zeyu, D’Antonio, Joshua P., Verga, Julia, Villanueva, Martin A., Castro, L. Nicolas Gonzalez, Tong, Yuzhou Evelyn, Saadi, Tariq Al, Chiocca, Andrew N., Fischer, David S., Heiland, Dieter Henrik, Guerriero, Jennifer L., Petrecca, Kevin, Suva, Mario L., Shalek, Alex K., Bernstein, Bradley E.
Publicado 2023

Multiple screening approaches reveal HDAC6 as a novel regulator of glycolytic metabolism in triple-negative breast cancer

por Dowling, Catríona M., Hollinshead, Kate E. R., Di Grande, Alessandra, Pritchard, Justin, Zhang, Hua, Dillon, Eugene T., Haley, Kathryn, Papadopoulos, Eleni, Mehta, Anita K., Bleach, Rachel, Lindner, Andreas U., Mooney, Brian, Düssmann, Heiko, O’Connor, Darran, Prehn, Jochen H. M., Wynne, Kieran, Hemann, Michael, Bradner, James E., Kimmelman, Alec C., Guerriero, Jennifer L., Cagney, Gerard, Wong, Kwok-Kin, Letai, Anthony G., Chonghaile, Tríona Ní
Publicado 2021

Considerations for treatment duration in responders to immune checkpoint inhibitors

por Marron, Thomas U, Ryan, Aideen E, Reddy, Sangeetha M, Kaczanowska, Sabina, Younis, Rania H, Thakkar, Dipti, Zhang, Jiajia, Bartkowiak, Todd, Howard, Rachel, Anderson, Kristin G, Olson, Daniel, Naqash, Abdul Rafeh, Patel, Ravi B, Sachdev, Esha, Rodriguez-Ruiz, Maria E, Sheffer, Michal, Church, Sarah, Fuhrman, Christopher, Overacre-Delgoffe, Abigail, Nguyen, Rosa, Florou, Vaia, Thaxton, Jessica E, Aggen, David H, Guerriero, Jennifer L
Publicado 2021

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

por Bi, Kevin, He, Meng Xiao, Bakouny, Ziad, Kanodia, Abhay, Napolitano, Sara, Wu, Jingyi, Grimaldi, Grace, Braun, David A., Cuoco, Michael S., Mayorga, Angie, DelloStritto, Laura, Bouchard, Gabrielle, Steinharter, John, Tewari, Alok K., Vokes, Natalie I., Shannon, Erin, Sun, Maxine, Park, Jihye, Chang, Steven L., McGregor, Bradley A., Haq, Rizwan, Denize, Thomas, Signoretti, Sabina, Guerriero, Jennifer L., Vigneau, Sébastien, Rozenblatt-Rosen, Orit, Rotem, Asaf, Regev, Aviv, Choueiri, Toni K., Van Allen, Eliezer M.
Publicado 2021

Molecular correlates of response to eribulin and pembrolizumab in hormone receptor-positive metastatic breast cancer

por Keenan, Tanya E., Guerriero, Jennifer L., Barroso-Sousa, Romualdo, Li, Tianyu, O’Meara, Tess, Giobbie-Hurder, Anita, Tayob, Nabihah, Hu, Jiani, Severgnini, Mariano, Agudo, Judith, Vaz-Luis, Ines, Anderson, Leilani, Attaya, Victoria, Park, Jihye, Conway, Jake, He, Meng Xiao, Reardon, Brendan, Shannon, Erin, Wulf, Gerburg, Spring, Laura M., Jeselsohn, Rinath, Krop, Ian, Lin, Nancy U., Partridge, Ann, Winer, Eric P., Mittendorf, Elizabeth A., Liu, David, Van Allen, Eliezer M., Tolaney, Sara M.
Publicado 2021

Supporting the Next Generation of Scientists to Lead Cancer Immunology Research

por Alspach, Elise, Chow, Ryan D., Demehri, Shadmehr, Guerriero, Jennifer L., Gujar, Shashi, Hartmann, Felix J., Helmink, Beth A., Hudson, William H., Ho, Won Jin, Ma, Leyuan, Maier, Barbara B., Maltez, Vivien I., Miller, Brian C., Moran, Amy E., Parry, Erin M., Pillai, Padmini S., Rafiq, Sarwish, Reina-Campos, Miguel, Rosato, Pamela C., Rudqvist, Nils-Petter, Ruhland, Megan K., Sagiv-Barfi, Idit, Sahu, Avinash Das, Samstein, Robert M., Schürch, Christian M., Sen, Debattama R., Thommen, Daniela S., Wolf, Yochai, Zappasodi, Roberta
Publicado 2021