4,5-Dihydro-5-Oxo-Pyrazolo[1,5-a]Thieno[2,3-c]Pyrimidine: A Novel Scaffold Containing Thiophene Ring. Chemical Reactivity and In Silico Studies to Predict the Profile to GABA(A) Re...

por Crocetti, Letizia, Guerrini, Gabriella, Melani, Fabrizio, Vergelli, Claudia, Giovannoni, Maria Paola
Publicado 2023

GABA(A) Receptor Modulators with a Pyrazolo[1,5-a]quinazoline Core: Synthesis, Molecular Modelling Studies and Electrophysiological Assays

por Crocetti, Letizia, Guerrini, Gabriella, Melani, Fabrizio, Vergelli, Claudia, Mascia, Maria Paola, Giovannoni, Maria Paola
Publicado 2022

Synthesis of New GABA(A) Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold

por Guerrini, Gabriella, Vergelli, Claudia, Cantini, Niccolò, Giovannoni, Maria Paola, Daniele, Simona, Mascia, Maria Paola, Martini, Claudia, Crocetti, Letizia
Publicado 2019

Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors

por Crocetti, Letizia, Giovannoni, Maria Paola, Cantini, Niccolò, Guerrini, Gabriella, Vergelli, Claudia, Schepetkin, Igor A., Khlebnikov, Andrei I., Quinn, Mark T.
Publicado 2020

Isoxazol-5(2H)-one: a new scaffold for potent human neutrophil elastase (HNE) inhibitors

por Vergelli, Claudia, Schepetkin, Igor A., Crocetti, Letizia, Iacovone, Antonella, Giovannoni, Maria Paola, Guerrini, Gabriella, Khlebnikov, Andrei I., Ciattini, Samuele, Ciciani, Giovanna, Quinn, Mark T.
Publicado 2017

New Panx-1 Blockers: Synthesis, Biological Evaluation and Molecular Dynamic Studies

por Crocetti, Letizia, Guerrini, Gabriella, Giovannoni, Maria Paola, Melani, Fabrizio, Lamanna, Silvia, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Ghelardini, Carla, Wang, Junjie, Dahl, Gerhard
Publicado 2022

Design, Synthesis and Pharmacological Evaluation of New Quinoline-Based Panx-1 Channel Blockers

por Crocetti, Letizia, Giovannoni, Maria Paola, Guerrini, Gabriella, Lamanna, Silvia, Melani, Fabrizio, Bartolucci, Gianluca, Pallecchi, Marco, Paoli, Paola, Lippi, Martina, Wang, Junjie, Dahl, Gerhard
Publicado 2023

Synthesis and analytical characterization of new thiazol-2-(3H)-ones as human neutrophil elastase (HNE) inhibitors

por Crocetti, Letizia, Bartolucci, Gianluca, Cilibrizzi, Agostino, Giovannoni, Maria Paola, Guerrini, Gabriella, Iacovone, Antonella, Menicatti, Marta, Schepetkin, Igor A., Khlebnikov, Andrei I., Quinn, Mark T., Vergelli, Claudia
Publicado 2017

Synthesis, biological evaluation, and molecular modelling studies of potent human neutrophil elastase (HNE) inhibitors

por Giovannoni, Maria Paola, Schepetkin, Igor A., Quinn, Mark T., Cantini, Niccolò, Crocetti, Letizia, Guerrini, Gabriella, Iacovone, Antonella, Paoli, Paola, Rossi, Patrizia, Bartolucci, Gianluca, Menicatti, Marta, Vergelli, Claudia
Publicado 2018

Synthesis, biological evaluation, molecular modeling, and structural analysis of new pyrazole and pyrazolone derivatives as N‐formyl peptide receptors agonists

por Vergelli, Claudia, Khlebnikov, Andrei I., Crocetti, Letizia, Guerrini, Gabriella, Cantini, Niccolò, Kirpotina, Liliya N., Schepetkin, Igor A., Cilibrizzi, Agostino, Quinn, Mark T., Rossi, Patrizia, Paoli, Paola, Giovannoni, Maria Paola
Publicado 2021

Pyridinone Derivatives as Interesting Formyl Peptide Receptor (FPR) Agonists for the Treatment of Rheumatoid Arthritis

por Crocetti, Letizia, Vergelli, Claudia, Guerrini, Gabriella, Giovannoni, Maria Paola, Kirpotina, Liliya N., Khlebnikov, Andrei I., Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Lucarini, Elena, Schepetkin, Igor A., Quinn, Mark T.
Publicado 2021