Computational Modeling of Hepatitis C Virus Envelope Glycoprotein Structure and Recognition

por Guest, Johnathan D., Pierce, Brian G.
Publicado 2018

Structure-Based and Rational Design of a Hepatitis C Virus Vaccine

por Guest, Johnathan D., Pierce, Brian G.
Publicado 2021

CoV3D: A database and resource for high resolution coronavirus protein structures

por Gowthaman, Ragul, Guest, Johnathan D., Yin, Rui, Adolf-Bryfogle, Jared, Schief, William R., Pierce, Brian G.
Publicado 2020

CoV3D: a database of high resolution coronavirus protein structures

por Gowthaman, Ragul, Guest, Johnathan D, Yin, Rui, Adolf-Bryfogle, Jared, Schief, William R, Pierce, Brian G
Publicado 2020

Structural and energetic profiling of SARS-CoV-2 receptor binding domain antibody recognition and the impact of circulating variants

por Yin, Rui, Guest, Johnathan D., Taherzadeh, Ghazaleh, Gowthaman, Ragul, Mittra, Ipsa, Quackenbush, Jane, Pierce, Brian G.
Publicado 2021

Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors

por Wu, Daichao, Kolesnikov, Alexander, Yin, Rui, Guest, Johnathan D., Gowthaman, Ragul, Shmelev, Anton, Serdyuk, Yana, Dianov, Dmitry V., Efimov, Grigory A., Pierce, Brian G., Mariuzza, Roy A.
Publicado 2022

Molecular Characterization of AZD7442 (Tixagevimab-Cilgavimab) Neutralization of SARS-CoV-2 Omicron Subvariants

por Roe, Tiffany L., Brady, Tyler, Schuko, Nicolette, Nguyen, Amy, Beloor, Jagadish, Guest, Johnathan D., Aksyuk, Anastasia A., Tuffy, Kevin M., Zhang, Tianhui, Streicher, Katie, Kelly, Elizabeth J., Kijak, Gustavo H.
Publicado 2023

Structure of engineered hepatitis C virus E1E2 ectodomain in complex with neutralizing antibodies

por Metcalf, Matthew C., Janus, Benjamin M., Yin, Rui, Wang, Ruixue, Guest, Johnathan D., Pozharski, Edwin, Law, Mansun, Mariuzza, Roy A., Toth, Eric A., Pierce, Brian G., Fuerst, Thomas R., Ofek, Gilad
Publicado 2023

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis

por Gopal, Radhika, Jackson, Kelli, Tzarum, Netanel, Kong, Leopold, Ettenger, Andrew, Guest, Johnathan, Pfaff, Jennifer M., Barnes, Trevor, Honda, Andrew, Giang, Erick, Davidson, Edgar, Wilson, Ian A., Doranz, Benjamin J., Law, Mansun
Publicado 2017

Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate

por Wang, Ruixue, Suzuki, Saori, Guest, Johnathan D., Heller, Brigitte, Almeda, Maricar, Andrianov, Alexander K., Marin, Alexander, Mariuzza, Roy A., Keck, Zhen-Yong, Foung, Steven K. H., Yunus, Abdul S., Pierce, Brian G., Toth, Eric A., Ploss, Alexander, Fuerst, Thomas R.
Publicado 2022

Antigenicity and Immunogenicity of Differentially Glycosylated Hepatitis C Virus E2 Envelope Proteins Expressed in Mammalian and Insect Cells

por Urbanowicz, Richard A., Wang, Ruixue, Schiel, John E., Keck, Zhen-yong, Kerzic, Melissa C., Lau, Patrick, Rangarajan, Sneha, Garagusi, Kyle J., Tan, Lei, Guest, Johnathan D., Ball, Jonathan K., Pierce, Brian G., Mariuzza, Roy A., Foung, Steven K. H., Fuerst, Thomas R.
Publicado 2019

Broadly neutralizing antibodies from an individual that naturally cleared multiple hepatitis C virus infections uncover molecular determinants for E2 targeting and vaccine design

por Keck, Zhen-Yong, Pierce, Brian G., Lau, Patrick, Lu, Janine, Wang, Yong, Underwood, Alexander, Bull, Rowena A., Prentoe, Jannick, Velázquez-Moctezuma, Rodrigo, Walker, Melanie R., Luciani, Fabio, Guest, Johnathan D., Fauvelle, Catherine, Baumert, Thomas F., Bukh, Jens, Lloyd, Andrew R., Foung, Steven K. H.
Publicado 2019

An Antigenically Diverse, Representative Panel of Envelope Glycoproteins for Hepatitis C Virus Vaccine Development

por Salas, Jordan H., Urbanowicz, Richard A., Guest, Johnathan D., Frumento, Nicole, Figueroa, Alexis, Clark, Kaitlyn E., Keck, Zhenyong, Cowton, Vanessa M., Cole, Sarah J., Patel, Arvind H., Fuerst, Thomas R., Drummer, Heidi E., Major, Marian, Tarr, Alexander W., Ball, Jonathan K., Law, Mansun, Pierce, Brian G., Foung, Steven K.H., Bailey, Justin R.
Publicado 2022

Molecular and phenotypic characteristics of RSV infections in infants during two nirsevimab randomized clinical trials

por Ahani, Bahar, Tuffy, Kevin M., Aksyuk, Anastasia A., Wilkins, Deidre, Abram, Michael E., Dagan, Ron, Domachowske, Joseph B., Guest, Johnathan D., Ji, Hong, Kushnir, Anna, Leach, Amanda, Madhi, Shabir A., Mankad, Vaishali S., Simões, Eric A. F., Sparklin, Benjamin, Speer, Scott D., Stanley, Ann Marie, Tabor, David E., Hamrén, Ulrika Wählby, Kelly, Elizabeth J., Villafana, Tonya
Publicado 2023