Structure-based mechanism of cysteine-switch latency and of catalysis by pappalysin-family metallopeptidases

por Guevara, Tibisay, Rodriguez-Banqueri, Arturo, Ksiazek, Miroslaw, Potempa, Jan, Gomis-Rüth, F. Xavier
Publicado 2020

Zymogenic latency in an ∼250-million-year-old astacin metallopeptidase

por Guevara, Tibisay, Rodríguez-Banqueri, Arturo, Stöcker, Walter, Becker-Pauly, Christoph, Gomis-Rüth, F. Xavier
Publicado 2022

Structure–Function Analysis of the Short Splicing Variant Carboxypeptidase Encoded by Drosophila melanogaster silver

por Tanco, Sebastián, Arolas, Joan L., Guevara, Tibisay, Lorenzo, Julia, Avilés, Francesc X., Gomis-Rüth, F. Xavier
Publicado 2010

Structural determinants of inhibition of Porphyromonas gingivalis gingipain K by KYT-36, a potent, selective, and bioavailable peptidase inhibitor

por Guevara, Tibisay, Rodríguez-Banqueri, Arturo, Lasica, Anna M., Ksiazek, Miroslaw, Potempa, Barbara A., Potempa, Jan, Gomis-Rüth, F. Xavier
Publicado 2019

Unique Structure and Stability of HmuY, a Novel Heme-Binding Protein of Porphyromonas gingivalis

por Wójtowicz, Halina, Guevara, Tibisay, Tallant, Cynthia, Olczak, Mariusz, Sroka, Aneta, Potempa, Jan, Solà, Maria, Olczak, Teresa, Gomis-Rüth, F. Xavier
Publicado 2009

An engineered protein-based submicromolar competitive inhibitor of the Staphylococcus aureus virulence factor aureolysin

por Mendes, Soraia R., Eckhard, Ulrich, Rodríguez-Banqueri, Arturo, Guevara, Tibisay, Czermak, Peter, Marcos, Enrique, Vilcinskas, Andreas, Gomis-Rüth, F. Xavier
Publicado 2022

Repositioning small molecule drugs as allosteric inhibitors of the BFT‐3 toxin from enterotoxigenic Bacteroides fragilis

por Jimenez‐Alesanco, Ana, Eckhard, Ulrich, Asencio del Rio, Marta, Vega, Sonia, Guevara, Tibisay, Velazquez‐Campoy, Adrian, Gomis‐Rüth, Francesc Xavier, Abian, Olga
Publicado 2022

The C-terminal region of human plasma fetuin-B is dispensable for the raised-elephant-trunk mechanism of inhibition of astacin metallopeptidases

por Guevara, Tibisay, Körschgen, Hagen, Cuppari, Anna, Schmitz, Carlo, Kuske, Michael, Yiallouros, Irene, Floehr, Julia, Jahnen-Dechent, Willi, Stöcker, Walter, Gomis-Rüth, F. Xavier
Publicado 2019

Structure and mechanism of a bacterial host-protein citrullinating virulence factor, Porphyromonas gingivalis peptidylarginine deiminase

por Goulas, Theodoros, Mizgalska, Danuta, Garcia-Ferrer, Irene, Kantyka, Tomasz, Guevara, Tibisay, Szmigielski, Borys, Sroka, Aneta, Millán, Claudia, Usón, Isabel, Veillard, Florian, Potempa, Barbara, Mydel, Piotr, Solà, Maria, Potempa, Jan, Gomis-Rüth, F. Xavier
Publicado 2015

Molecular and in vivo studies of a glutamate-class prolyl-endopeptidase for coeliac disease therapy

por del Amo-Maestro, Laura, Mendes, Soraia R., Rodríguez-Banqueri, Arturo, Garzon-Flores, Laura, Girbal, Marina, Rodríguez-Lagunas, María José, Guevara, Tibisay, Franch, Àngels, Pérez-Cano, Francisco J., Eckhard, Ulrich, Gomis-Rüth, F. Xavier
Publicado 2022

De novo design of immunoglobulin-like domains

por Chidyausiku, Tamuka M., Mendes, Soraia R., Klima, Jason C., Nadal, Marta, Eckhard, Ulrich, Roel-Touris, Jorge, Houliston, Scott, Guevara, Tibisay, Haddox, Hugh K., Moyer, Adam, Arrowsmith, Cheryl H., Gomis-Rüth, F. Xavier, Baker, David, Marcos, Enrique
Publicado 2022

Structure of mammalian plasma fetuin-B and its mechanism of selective metallopeptidase inhibition

por Cuppari, Anna, Körschgen, Hagen, Fahrenkamp, Dirk, Schmitz, Carlo, Guevara, Tibisay, Karmilin, Konstantin, Kuske, Michael, Olf, Mario, Dietzel, Eileen, Yiallouros, Irene, de Sanctis, Daniele, Goulas, Theodoros, Weiskirchen, Ralf, Jahnen-Dechent, Willi, Floehr, Julia, Stoecker, Walter, Jovine, Luca, Gomis-Rüth, F. Xavier
Publicado 2019

Structural and functional probing of PorZ, an essential bacterial surface component of the type-IX secretion system of human oral-microbiomic Porphyromonas gingivalis.

por Lasica, Anna M., Goulas, Theodoros, Mizgalska, Danuta, Zhou, Xiaoyan, de Diego, Iñaki, Ksiazek, Mirosław, Madej, Mariusz, Guo, Yonghua, Guevara, Tibisay, Nowak, Magdalena, Potempa, Barbara, Goel, Apoorv, Sztukowska, Maryta, Prabhakar, Apurva T., Bzowska, Monika, Widziolek, Magdalena, Thøgersen, Ida B., Enghild, Jan J., Simonian, Mary, Kulczyk, Arkadiusz W., Nguyen, Ky-Anh, Potempa, Jan, Gomis-Rüth, F. Xavier
Publicado 2016

A unique network of attack, defence and competence on the outer membrane of the periodontitis pathogen Tannerella forsythia

por Książek, Mirosław, Goulas, Theodoros, Mizgalska, Danuta, Rodríguez-Banqueri, Arturo, Eckhard, Ulrich, Veillard, Florian, Waligórska, Irena, Benedyk-Machaczka, Małgorzata, Sochaj-Gregorczyk, Alicja M., Madej, Mariusz, Thøgersen, Ida B., Enghild, Jan J., Cuppari, Anna, Arolas, Joan L., de Diego, Iñaki, López-Pelegrín, Mar, Garcia-Ferrer, Irene, Guevara, Tibisay, Dive, Vincent, Zani, Marie-Louise, Moreau, Thierry, Potempa, Jan, Gomis-Rüth, F. Xavier
Publicado 2022