A Small Molecule Reacts with the p53 Somatic Mutant Y220C to Rescue Wild-type Thermal Stability

por Guiley, Keelan Z., Shokat, Kevan M.
Publicado 2023

Chemical acylation of an acquired serine suppresses oncogenic signaling of K-Ras(G12S)

por Zhang, Ziyang, Guiley, Keelan Z., Shokat, Kevan M.
Publicado 2022

Single-pot enzymatic synthesis of Dicer-substrate siRNAs

por Guiley, Keelan Z., Pratt, Ashley J., MacRae, Ian J.
Publicado 2012

Chemoselective Covalent Modification of K-Ras(G12R) with a Small Molecule Electrophile

por Zhang, Ziyang, Morstein, Johannes, Ecker, Andrew K., Guiley, Keelan Z., Shokat, Kevan M.
Publicado 2022

Cyclin-dependent kinase-mediated phosphorylation and the negative regulatory domain of transcription factor B-Myb modulate its DNA binding

por Wijeratne, Tilini U., Guiley, Keelan Z., Lee, Hsiau-Wei, Müller, Gerd A., Rubin, Seth M.
Publicado 2022

The Molecular Architecture of Human Dicer

por Lau, Pick-Wei, Guiley, Keelan Z., De, Nabanita, Potter, Clinton S., Carragher, Bridget, MacRae, Ian J.
Publicado 2012

Structural mechanisms of DREAM complex assembly and regulation

por Guiley, Keelan Z., Liban, Tyler J., Felthousen, Jessica G., Ramanan, Parameshwaran, Litovchick, Larisa, Rubin, Seth M.
Publicado 2015

The cell cycle regulatory DREAM complex is disrupted by high expression of oncogenic B-Myb

por Iness, Audra N., Felthousen, Jessica, Ananthapadmanabhan, Varsha, Sesay, Fatmata, Saini, Siddharth, Guiley, Keelan Z., Rubin, Seth M., Dozmorov, Mikhail, Litovchick, Larisa
Publicado 2018

A long lost key opens an ancient lock: Drosophila Myb causes a synthetic multivulval phenotype in nematodes

por Vorster, Paul J., Goetsch, Paul, Wijeratne, Tilini U., Guiley, Keelan Z., Andrejka, Laura, Tripathi, Sarvind, Larson, Braden J., Rubin, Seth M., Strome, Susan, Lipsick, Joseph S.
Publicado 2020

The MuvB complex binds and stabilizes nucleosomes downstream of the transcription start site of cell-cycle dependent genes

por Asthana, Anushweta, Ramanan, Parameshwaran, Hirschi, Alexander, Guiley, Keelan Z., Wijeratne, Tilini U., Shelansky, Robert, Doody, Michael J., Narasimhan, Haritha, Boeger, Hinrich, Tripathi, Sarvind, Müller, Gerd A., Rubin, Seth M.
Publicado 2022