Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors

por Wang, Yannick, Wozniak, Agnieszka, Wellens, Jasmien, Gebreyohannes, Yemarshet K., Guillén, Maria Jose, Avilés, Pablo M., Debiec-Rychter, Maria, Sciot, Raf, Schöffski, Patrick
Publicado 2020

Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models

por Céspedes, María Virtudes, Guillén, María José, López-Casas, Pedro Pablo, Sarno, Francesca, Gallardo, Alberto, Álamo, Patricia, Cuevas, Carmen, Hidalgo, Manuel, Galmarini, Carlos María, Allavena, Paola, Avilés, Pablo, Mangues, Ramón
Publicado 2016

CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110

por Domínguez, Juan Manuel, Pérez-Chacón, Gema, Guillén, María José, Muñoz-Alonso, María José, Somovilla-Crespo, Beatriz, Cibrián, Danay, Acosta-Iborra, Bárbara, Adrados, Magdalena, Muñoz-Calleja, Cecilia, Cuevas, Carmen, Sánchez-Madrid, Francisco, Avilés, Pablo, Zapata, Juan M.
Publicado 2020

Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A

por White, Kris M., Rosales, Romel, Yildiz, Soner, Kehrer, Thomas, Miorin, Lisa, Moreno, Elena, Jangra, Sonia, Uccellini, Melissa B., Rathnasinghe, Raveen, Coughlan, Lynda, Martinez-Romero, Carles, Batra, Jyoti, Rojc, Ajda, Bouhaddou, Mehdi, Fabius, Jacqueline M., Obernier, Kirsten, Dejosez, Marion, Guillén, María José, Losada, Alejandro, Avilés, Pablo, Schotsaert, Michael, Zwaka, Thomas, Vignuzzi, Marco, Shokat, Kevan M., Krogan, Nevan J., García-Sastre, Adolfo
Publicado 2021