Heterogeneity of Phosphatidylinositol-3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin Activation in Cancer: Is PI3K Isoform Specificity Important?

por Cintas, Célia, Guillermet-Guibert, Julie
Publicado 2018

Transducing compressive forces into cellular outputs in cancer and beyond

por Schmitter, Céline, Di-Luoffo, Mickaël, Guillermet-Guibert, Julie
Publicado 2023

Targeting Class I-II-III PI3Ks in Cancer Therapy: Recent Advances in Tumor Biology and Preclinical Research

por Thibault, Benoît, Ramos-Delgado, Fernanda, Guillermet-Guibert, Julie
Publicado 2023

Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor

por Berenjeno, Inma M., Guillermet-Guibert, Julie, Pearce, Wayne, Gray, Alexander, Fleming, Stewart, Vanhaesebroeck, Bart
Publicado 2012

Loss of p27(Kip1) promotes metaplasia in the pancreas via the regulation of Sox9 expression

por Jeannot, Pauline, Callot, Caroline, Baer, Romain, Duquesnes, Nicolas, Guerra, Carmen, Guillermet-Guibert, Julie, Bachs, Oriol, Besson, Arnaud
Publicado 2015

Signal-Targeted Therapies and Resistance Mechanisms in Pancreatic Cancer: Future Developments Reside in Proteomics

por Cintas, Célia, Douché, Thibaut, Therville, Nicole, Arcucci, Silvia, Ramos-Delgado, Fernanda, Basset, Céline, Thibault, Benoît, Guillermet-Guibert, Julie
Publicado 2018

Experimental pancreatic cancer develops in soft pancreas: novel leads for an individualized diagnosis by ultrafast elasticity imaging

por Therville, Nicole, Arcucci, Silvia, Vertut, Aurélie, Ramos-Delgado, Fernanda, Da Mota, Dina Ferreira, Dufresne, Marlène, Basset, Céline, Guillermet-Guibert, Julie
Publicado 2019

Effect of combined inhibition of p110 alpha PI3K isoform and STAT3 pathway in ovarian cancer platinum-based resistance

por Le Naour, Augustin, Mevel, Renaud, Thibault, Benoit, Courtais, Elise, Chantalat, Elodie, Delord, Jean Pierre, Couderc, Bettina, Guillermet-Guibert, Julie, Martinez, Alejandra
Publicado 2018

Inhibition of the p110α isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis

por Soler, Adriana, Serra, Helena, Pearce, Wayne, Angulo, Ana, Guillermet-Guibert, Julie, Friedman, Lori S., Viñals, Francesc, Gerhardt, Holger, Casanovas, Oriol, Graupera, Mariona, Vanhaesebroeck, Bart
Publicado 2013

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

por Baer, Romain, Cintas, Célia, Dufresne, Marlène, Cassant-Sourdy, Stéphanie, Schönhuber, Nina, Planque, Laetitia, Lulka, Hubert, Couderc, Bettina, Bousquet, Corinne, Garmy-Susini, Barbara, Vanhaesebroeck, Bart, Pyronnet, Stéphane, Saur, Dieter, Guillermet-Guibert, Julie
Publicado 2014

Pancreatic preneoplastic lesions plasma signatures and biomarkers based on proteome profiling of mouse models

por Ligat, Laetitia, Saint-Laurent, Nathalie, El-Mrani, Aïcha, Gigoux, Véronique, Al Saati, Talal, Tomasini, Richard, Nigri, Jérémy, Dejean, Sébastien, Pont, Frédéric, Baer, Romain, Guillermet-Guibert, Julie, Cordelier, Pierre, Lopez, Frédéric, Dufresne, Marlène
Publicado 2015

Paclitaxel induces lymphatic endothelial cells autophagy to promote metastasis

por Zamora, Audrey, Alves, Melinda, Chollet, Charlotte, Therville, Nicole, Fougeray, Tiffany, Tatin, Florence, Franchet, Camille, Gomez-Brouchet, Anne, Vaysse, Charlotte, Martinez, Laurent O., Najib, Souad, Guillermet-Guibert, Julie, Lacazette, Eric, Prats, Anne-Catherine, Garmy-Susini, Barbara
Publicado 2019

Novel Role for p110β PI 3-Kinase in Male Fertility through Regulation of Androgen Receptor Activity in Sertoli Cells

por Guillermet-Guibert, Julie, Smith, Lee B., Halet, Guillaume, Whitehead, Maria A., Pearce, Wayne, Rebourcet, Diane, León, Kelly, Crépieux, Pascale, Nock, Gemma, Strömstedt, Maria, Enerback, Malin, Chelala, Claude, Graupera, Mariona, Carroll, John, Cosulich, Sabina, Saunders, Philippa T. K., Huhtaniemi, Ilpo, Vanhaesebroeck, Bart
Publicado 2015

Upregulated Apelin Signaling in Pancreatic Cancer Activates Oncogenic Signaling Pathways to Promote Tumor Development

por Chaves-Almagro, Carline, Auriau, Johanna, Dortignac, Alizée, Clerc, Pascal, Lulka, Hubert, Deleruyelle, Simon, Projetti, Fabrice, Nakhlé, Jessica, Frances, Audrey, Berta, Judit, Gigoux, Véronique, Fourmy, Daniel, Dufresne, Marlène, Gomez-Brouchet, Anne, Guillermet-Guibert, Julie, Cordelier, Pierre, Knibiehler, Bernard, Jockers, Ralf, Valet, Philippe, Audigier, Yves, Masri, Bernard
Publicado 2022

Dominant Role of the p110β Isoform of PI3K over p110α in Energy Homeostasis Regulation by POMC and AgRP Neurons

por Al-Qassab, Hind, Smith, Mark A., Irvine, Elaine E., Guillermet-Guibert, Julie, Claret, Marc, Choudhury, Agharul I., Selman, Colin, Piipari, Kaisa, Clements, Melanie, Lingard, Steven, Chandarana, Keval, Bell, Jimmy D., Barsh, Gregory S., Smith, Andrew J.H., Batterham, Rachel L., Ashford, Michael L.J., Vanhaesebroeck, Bart, Withers, Dominic J.
Publicado 2009

Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component

por Thibault, Benoit, Ramos‐Delgado, Fernanda, Pons‐Tostivint, Elvire, Therville, Nicole, Cintas, Celia, Arcucci, Silvia, Cassant‐Sourdy, Stephanie, Reyes‐Castellanos, Gabriela, Tosolini, Marie, Villard, Amelie V, Cayron, Coralie, Baer, Romain, Bertrand‐Michel, Justine, Pagan, Delphine, Ferreira Da Mota, Dina, Yan, Hongkai, Falcomatà, Chiara, Muscari, Fabrice, Bournet, Barbara, Delord, Jean‐Pierre, Aksoy, Ezra, Carrier, Alice, Cordelier, Pierre, Saur, Dieter, Basset, Celine, Guillermet‐Guibert, Julie
Publicado 2021