Mechanisms for Maintaining Eukaryotic Replisome Progression in the Presence of DNA Damage

por Guilliam, Thomas A.
Publicado 2021

PrimPol—Prime Time to Reprime

por Guilliam, Thomas A., Doherty, Aidan J.
Publicado 2017

The eukaryotic replisome tolerates leading‐strand base damage by replicase switching

por Guilliam, Thomas A, Yeeles, Joseph TP
Publicado 2021

Primase-polymerases are a functionally diverse superfamily of replication and repair enzymes

por Guilliam, Thomas A., Keen, Benjamin A., Brissett, Nigel C., Doherty, Aidan J.
Publicado 2015

PolDIP2 interacts with human PrimPol and enhances its DNA polymerase activities

por Guilliam, Thomas A., Bailey, Laura J., Brissett, Nigel C., Doherty, Aidan J.
Publicado 2016

PrimPol Is Required for Replicative Tolerance of G Quadruplexes in Vertebrate Cells

por Schiavone, Davide, Jozwiakowski, Stanislaw K., Romanello, Marina, Guilbaud, Guillaume, Guilliam, Thomas A., Bailey, Laura J., Sale, Julian E., Doherty, Aidan J.
Publicado 2016

Repriming by PrimPol is critical for DNA replication restart downstream of lesions and chain-terminating nucleosides

por Kobayashi, Kaori, Guilliam, Thomas A., Tsuda, Masataka, Yamamoto, Junpei, Bailey, Laura J., Iwai, Shigenori, Takeda, Shunichi, Doherty, Aidan J., Hirota, Kouji
Publicado 2016

R‐loop formation during S phase is restricted by PrimPol‐mediated repriming

por Šviković, Saša, Crisp, Alastair, Tan‐Wong, Sue Mei, Guilliam, Thomas A, Doherty, Aidan J, Proudfoot, Nicholas J, Guilbaud, Guillaume, Sale, Julian E
Publicado 2018

Molecular basis for PrimPol recruitment to replication forks by RPA

por Guilliam, Thomas A., Brissett, Nigel C., Ehlinger, Aaron, Keen, Benjamin A., Kolesar, Peter, Taylor, Elaine M., Bailey, Laura J., Lindsay, Howard D., Chazin, Walter J., Doherty, Aidan J.
Publicado 2017

Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins

por Guilliam, Thomas A., Jozwiakowski, Stanislaw K., Ehlinger, Aaron, Barnes, Ryan P., Rudd, Sean G., Bailey, Laura J., Skehel, J. Mark, Eckert, Kristin A., Chazin, Walter J., Doherty, Aidan J.
Publicado 2015