Tools for the Quality Control of Pharmaceutical Heparin

por Devlin, Anthony, Mycroft-West, Courtney, Procter, Patricia, Cooper, Lynsay, Guimond, Scott, Lima, Marcelo, Yates, Edwin, Skidmore, Mark
Publicado 2019

Rapid Purification and High Sensitivity Analysis of Heparan Sulfate from Cells and Tissues: TOWARD GLYCOMICS PROFILING

por Guimond, Scott E., Puvirajesinghe, Tania M., Skidmore, Mark A., Kalus, Ina, Dierks, Thomas, Yates, Edwin A., Turnbull, Jeremy E.
Publicado 2009

2-O Heparan Sulfate Sulfation by Hs2st Is Required for Erk/Mapk Signalling Activation at the Mid-Gestational Mouse Telencephalic Midline

por Chan, Wai Kit, Howe, Katherine, Clegg, James M., Guimond, Scott E., Price, David J., Turnbull, Jeremy E., Pratt, Thomas
Publicado 2015

A semi-synthetic glycosaminoglycan analogue inhibits and reverses Plasmodium falciparum cytoadherence

por Skidmore, Mark A., Mustaffa, Khairul Mohd Fadzli, Cooper, Lynsay C., Guimond, Scott E., Yates, Edwin A., Craig, Alister G.
Publicado 2017

Variations in the Peritrophic Matrix Composition of Heparan Sulphate from the Tsetse Fly, Glossina morsitans morsitans

por Rogerson, Evelyn, Pelletier, Julien, Acosta-Serrano, Alvaro, Rose, Clair, Taylor, Sarah, Guimond, Scott, Lima, Marcelo, Skidmore, Mark, Yates, Edwin
Publicado 2018

Sulfatase‐mediated manipulation of the astrocyte‐Schwann cell interface

por O'Neill, Paul, Lindsay, Susan L., Pantiru, Andreea, Guimond, Scott E., Fagoe, Nitish, Verhaagen, Joost, Turnbull, Jeremy E., Riddell, John S., Barnett, Susan C.
Publicado 2016

Sulf1 and Sulf2 Differentially Modulate Heparan Sulfate Proteoglycan Sulfation during Postnatal Cerebellum Development: Evidence for Neuroprotective and Neurite Outgrowth Promoting...

por Kalus, Ina, Rohn, Susanne, Puvirajesinghe, Tania M., Guimond, Scott E., Eyckerman-Kölln, Pieter J., ten Dam, Gerdy, van Kuppevelt, Toin H., Turnbull, Jeremy E., Dierks, Thomas
Publicado 2015

High sensitivity (zeptomole) detection of BODIPY-labelled heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts

por Maciej-Hulme, Marissa L., Leprince, Anaëlle C. N., Lavin, Andre, Guimond, Scott E., Turnbull, Jeremy E., Pelletier, Julien, Yates, Edwin A., Powell, Andrew K., Skidmore, Mark A.
Publicado 2023

A Glycosaminoglycan Extract from Portunus pelagicus Inhibits BACE1, the β Secretase Implicated in Alzheimer’s Disease

por Mycroft-West, Courtney J., Cooper, Lynsay C., Devlin, Anthony J., Procter, Patricia, Guimond, Scott E., Guerrini, Marco, Fernig, David G., Lima, Marcelo A., Yates, Edwin A., Skidmore, Mark A.
Publicado 2019

Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis

por Duckworth, Carrie A., Guimond, Scott E., Sindrewicz, Paulina, Hughes, Ashley J., French, Neil S., Lian, Lu-Yun, Yates, Edwin A., Pritchard, D. Mark, Rhodes, Jonathan M., Turnbull, Jeremy E., Yu, Lu-Gang
Publicado 2015

Inhibition of BACE1, the β-secretase implicated in Alzheimer’s disease, by a chondroitin sulfate extract from Sardina pilchardus

por Mycroft-West, Courtney J., Devlin, Anthony J., Cooper, Lynsay C., Procter, Patricia, Miller, Gavin J., Fernig, David G., Guerrini, Marco, Guimond, Scott E., Lima, Marcelo A., Yates, Edwin A., Skidmore, Mark Andrew
Publicado 2020

Glycosaminoglycans from Litopenaeus vannamei Inhibit the Alzheimer’s Disease β Secretase, BACE1

por Mycroft-West, Courtney J., Devlin, Anthony J., Cooper, Lynsay C., Guimond, Scott E., Procter, Patricia, Guerrini, Marco, Miller, Gavin J., Fernig, David G., Yates, Edwin A., Lima, Marcelo A., Skidmore, Mark A.
Publicado 2021

Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides

por Miller, Rebecca L., Guimond, Scott E., Schwörer, Ralf, Zubkova, Olga V., Tyler, Peter C., Xu, Yongmei, Liu, Jian, Chopra, Pradeep, Boons, Geert-Jan, Grabarics, Márkó, Manz, Christian, Hofmann, Johanna, Karlsson, Niclas G., Turnbull, Jeremy E., Struwe, Weston B., Pagel, Kevin
Publicado 2020

The Hyperlipidaemic Drug Fenofibrate Significantly Reduces Infection by SARS-CoV-2 in Cell Culture Models

por Davies, Scott P., Mycroft-West, Courtney J., Pagani, Isabel, Hill, Harriet J., Chen, Yen-Hsi, Karlsson, Richard, Bagdonaite, Ieva, Guimond, Scott E., Stamataki, Zania, De Lima, Marcelo Andrade, Turnbull, Jeremy E., Yang, Zhang, Vicenzi, Elisa, Skidmore, Mark A., Khanim, Farhat L., Richardson, Alan
Publicado 2021

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 by Disrupting the Spike–ACE2 Interaction

por Guimond, Scott E., Mycroft-West, Courtney J., Gandhi, Neha S., Tree, Julia A., Le, Thuy T., Spalluto, C. Mirella, Humbert, Maria V., Buttigieg, Karen R., Coombes, Naomi, Elmore, Michael J., Wand, Matthew, Nyström, Kristina, Said, Joanna, Setoh, Yin Xiang, Amarilla, Alberto A., Modhiran, Naphak, Sng, Julian D. J., Chhabra, Mohit, Young, Paul R., Rawle, Daniel J., Lima, Marcelo A., Yates, Edwin A., Karlsson, Richard, Miller, Rebecca L., Chen, Yen-Hsi, Bagdonaite, Ieva, Yang, Zhang, Stewart, James, Nguyen, Dung, Laidlaw, Stephen, Hammond, Edward, Dredge, Keith, Wilkinson, Tom M. A., Watterson, Daniel, Khromykh, Alexander A., Suhrbier, Andreas, Carroll, Miles W., Trybala, Edward, Bergström, Tomas, Ferro, Vito, Skidmore, Mark A., Turnbull, Jeremy E.
Publicado 2022