KInhibition: A Kinase Inhibitor Selection Portal

por Bello, Thomas, Gujral, Taranjit S.
Publicado 2018

Non-linear Deep Neural Network for Rapid and Accurate Prediction of Phenotypic Responses to Kinase Inhibitors

por Vijay, Siddharth, Gujral, Taranjit S.
Publicado 2020

A System-Wide Investigation of the Dynamics of Wnt Signaling Reveals Novel Phases of Transcriptional Regulation

por Gujral, Taranjit S., MacBeath, Gavin
Publicado 2010

Emerging approaches to study cell–cell interactions in tumor microenvironment

por Nishida-Aoki, Nao, Gujral, Taranjit S.
Publicado 2019

Proteomic and Transcriptomic Profiling Reveals Mitochondrial Oxidative Phosphorylation as Therapeutic Vulnerability in Androgen Receptor Pathway Active Prostate Tumors

por Xue, Caroline, Corey, Eva, Gujral, Taranjit S.
Publicado 2022

Deep neural network modeling identifies biomarkers of response to immune-checkpoint therapy

por Kang, Yuqi, Vijay, Siddharth, Gujral, Taranjit S.
Publicado 2022

Olverembatinib inhibits SARS‐CoV‐2‐Omicron variant‐mediated cytokine release in human peripheral blood mononuclear cells

por Chan, Marina, Holland, Eric C, Gujral, Taranjit S
Publicado 2022

Utilizing preclinical models to develop targeted therapies for rare central nervous system cancers

por Arakaki, Aleena K S, Szulzewsky, Frank, Gilbert, Mark R, Gujral, Taranjit S, Holland, Eric C
Publicado 2021

Anesthetics inhibit phosphorylation of the ribosomal protein S6 in mouse cultured cortical cells and developing brain

por Friese, Matthew B., Gujral, Taranjit S., Palanisamy, Arvind, Hemmer, Brittany, Culley, Deborah J., Crosby, Gregory
Publicado 2023

Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib

por MacLeod, James A., Gao, Yan, Hall, Christine, Muller, William J., Gujral, Taranjit S., Greer, Peter A.
Publicado 2018

Machine learning identifies molecular regulators and therapeutics for targeting SARS‐CoV2‐induced cytokine release

por Chan, Marina, Vijay, Siddharth, McNevin, John, McElrath, M Juliana, Holland, Eric C, Gujral, Taranjit S
Publicado 2021

Computational modeling identifies multitargeted kinase inhibitors as effective therapies for metastatic, castration-resistant prostate cancer

por Bello, Thomas, Paindelli, Claudia, Diaz-Gomez, Luis A., Melchiorri, Anthony, Mikos, Antonios G., Nelson, Peter S., Dondossola, Eleonora, Gujral, Taranjit S.
Publicado 2021

Organotypic Models for Functional Drug Testing of Human Cancers

por Huang, Yu Ling, Dickerson, Lindsay K., Kenerson, Heidi, Jiang, Xiuyun, Pillarisetty, Venu, Tian, Qiang, Hood, Leroy, Gujral, Taranjit S., Yeung, Raymond S.
Publicado 2023

Identifying host regulators and inhibitors of liver stage malaria infection using kinase activity profiles

por Arang, Nadia, Kain, Heather S., Glennon, Elizabeth K., Bello, Thomas, Dudgeon, Denali R., Walter, Emily N. F., Gujral, Taranjit S., Kaushansky, Alexis
Publicado 2017

Polypharmacology-based kinome screen identifies new regulators of KSHV reactivation

por Olson, Annabel T., Kang, Yuqi, Ladha, Anushka M., Zhu, Songli, Lim, Chuan Bian, Nabet, Behnam, Lagunoff, Michael, Gujral, Taranjit S., Geballe, Adam P.
Publicado 2023

Organotypic tumor slice cultures provide a versatile platform for immuno-oncology and drug discovery

por Sivakumar, Ramya, Chan, Marina, Shin, Jiye Stella, Nishida-Aoki, Nao, Kenerson, Heidi L., Elemento, Olivier, Beltran, Himisha, Yeung, Raymond, Gujral, Taranjit S.
Publicado 2019

KiRNet: Kinase-centered network propagation of pharmacological screen results

por Bello, Thomas, Chan, Marina, Golkowski, Martin, Xue, Andrew G., Khasnavis, Nithisha, Ceribelli, Michele, Ong, Shao-En, Thomas, Craig J., Gujral, Taranjit S.
Publicado 2021

Both YAP1-MAML2 and constitutively active YAP1 drive the formation of tumors that resemble NF2 mutant meningiomas in mice

por Szulzewsky, Frank, Arora, Sonali, Arakaki, Aleena K.S., Sievers, Philipp, Almiron Bonnin, Damian A., Paddison, Patrick J., Sahm, Felix, Cimino, Patrick J., Gujral, Taranjit S., Holland, Eric C.
Publicado 2022

Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis

por Szulzewsky, Frank, Arora, Sonali, Hoellerbauer, Pia, King, Claire, Nathan, Erica, Chan, Marina, Cimino, Patrick J., Ozawa, Tatsuya, Kawauchi, Daisuke, Pajtler, Kristian W., Gilbertson, Richard J., Paddison, Patrick J., Vasioukhin, Valeri, Gujral, Taranjit S., Holland, Eric C.
Publicado 2020

Kinesin superfamily protein Kif26b links Wnt5a-Ror signaling to the control of cell and tissue behaviors in vertebrates

por Susman, Michael W, Karuna, Edith P, Kunz, Ryan C, Gujral, Taranjit S, Cantú, Andrea V, Choi, Shannon S, Jong, Brigette Y, Okada, Kyoko, Scales, Michael K, Hum, Jennie, Hu, Linda S, Kirschner, Marc W, Nishinakamura, Ryuichi, Yamada, Soichiro, Laird, Diana J, Jao, Li-En, Gygi, Steven P, Greenberg, Michael E, Ho, Hsin-Yi Henry
Publicado 2017