Inhibitors of Bcl-2 protein family deplete ER Ca(2+) stores in pancreatic acinar cells

por Gerasimenko, Julia, Ferdek, Pawel, Fischer, Lars, Gukovskaya, Anna S., Pandol, Stephen J.
Publicado 2010

Protein Kinase D Regulates Cell Death Pathways in Experimental Pancreatitis

por Yuan, Jingzhen, Liu, Yannan, Tan, Tanya, Guha, Sushovan, Gukovsky, Ilya, Gukovskaya, Anna, Pandol, Stephen J.
Publicado 2012

Rab9 Mediates Pancreatic Autophagy Switch From Canonical to Noncanonical, Aggravating Experimental Pancreatitis

por Mareninova, Olga A., Dillon, Dustin L., Wightman, Carli J.M., Yakubov, Iskandar, Takahashi, Toshimasa, Gaisano, Herbert Y., Munson, Keith, Ohmuraya, Masaki, Dawson, David, Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado 2021

Cathepsin B-Mediated Activation of Trypsinogen in Endocytosing Macrophages Increases Severity of Pancreatitis in Mice

por Sendler, Matthias, Weiss, Frank-Ulrich, Golchert, Janine, Homuth, Georg, van den Brandt, Cindy, Mahajan, Ujjwal M., Partecke, Lars-Ivo, Döring, Paula, Gukovsky, Ilya, Gukovskaya, Anna S., Wagh, Preshit R., Lerch, Markus M., Mayerle, Julia
Publicado 2018

Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome

por Sakata, Kazuya, Araki, Kimi, Nakano, Hiroyasu, Nishina, Takashi, Komazawa-Sakon, Sachiko, Murai, Shin, Lee, Grace E., Hashimoto, Daisuke, Suzuki, Chigure, Uchiyama, Yasuo, Notohara, Kenji, Gukovskaya, Anna S., Gukovsky, Ilya, Yamamura, Ken-ichi, Baba, Hideo, Ohmuraya, Masaki
Publicado 2016

Lysosome-Associated Membrane Proteins (LAMP) Maintain Pancreatic Acinar Cell Homeostasis: LAMP-2–Deficient Mice Develop Pancreatitis

por Mareninova, Olga A., Sendler, Matthias, Malla, Sudarshan Ravi, Yakubov, Iskandar, French, Samuel W., Tokhtaeva, Elmira, Vagin, Olga, Oorschot, Viola, Lüllmann-Rauch, Renate, Blanz, Judith, Dawson, David, Klumperman, Judith, Lerch, Markus M., Mayerle, Julia, Gukovsky, Ilya, Gukovskaya, Anna S.
Publicado 2015

Incidence of pancreatic cancer is dramatically increased by a high fat, high calorie diet in KrasG12D mice

por Chang, Hui-Hua, Moro, Aune, Takakura, Kazuki, Su, Hsin-Yuan, Mo, Allen, Nakanishi, Masako, Waldron, Richard T., French, Samuel W., Dawson, David W., Hines, O. Joe, Li, Gang, Go, Vay Liang W., Sinnett-Smith, James, Pandol, Stephen J., Lugea, Aurelia, Gukovskaya, Anna S., Duff, Michael O., Rosenberg, Daniel W., Rozengurt, Enrique, Eibl, Guido
Publicado 2017

Mechanism of mitochondrial permeability transition pore induction and damage in the pancreas: inhibition prevents acute pancreatitis by protecting production of ATP

por Mukherjee, Rajarshi, Mareninova, Olga A, Odinokova, Irina V, Huang, Wei, Murphy, John, Chvanov, Michael, Javed, Muhammad A, Wen, Li, Booth, David M, Cane, Matthew C, Awais, Muhammad, Gavillet, Bruno, Pruss, Rebecca M, Schaller, Sophie, Molkentin, Jeffery D, Tepikin, Alexei V, Petersen, Ole H, Pandol, Stephen J, Gukovsky, Ilya, Criddle, David N, Gukovskaya, Anna S, Sutton, Robert
Publicado 2016