Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease

por Gumeni, Sentiljana, Trougakos, Ioannis P.
Publicado 2016

Differential Dose- and Tissue-Dependent Effects of foxo on Aging, Metabolic and Proteostatic Pathways

por Manola, Maria S., Gumeni, Sentiljana, Trougakos, Ioannis P.
Publicado 2021

Boosting autophagy in anti-tumor proteasome inhibition-mediated cardiotoxicity

por Papanagnou, Eleni-Dimitra, Gumeni, Sentiljana, Trougakos, Ioannis P.
Publicado 2023

Hereditary Spastic Paraplegia and Future Therapeutic Directions: Beneficial Effects of Small Compounds Acting on Cellular Stress

por Gumeni, Sentiljana, Vantaggiato, Chiara, Montopoli, Monica, Orso, Genny
Publicado 2021

Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach

por Evangelakou, Zoi, Manola, Maria, Gumeni, Sentiljana, Trougakos, Ioannis P.
Publicado 2019

Proteome Stability as a Key Factor of Genome Integrity

por Gumeni, Sentiljana, Evangelakou, Zoi, Gorgoulis, Vassilis G., Trougakos, Ioannis P.
Publicado 2017

Nrf2 activation induces mitophagy and reverses Parkin/Pink1 knock down-mediated neuronal and muscle degeneration phenotypes

por Gumeni, Sentiljana, Papanagnou, Eleni-Dimitra, Manola, Maria S., Trougakos, Ioannis P.
Publicado 2021

Sustained Nrf2 Overexpression-Induced Metabolic Deregulation Can Be Attenuated by Modulating Insulin/Insulin-like Growth Factor Signaling

por Gumeni, Sentiljana, Lamprou, Maria, Evangelakou, Zoi, Manola, Maria S., Trougakos, Ioannis P.
Publicado 2023

Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics

por Gumeni, Sentiljana, Evangelakou, Zoi, Tsakiri, Eleni N., Scorrano, Luca, Trougakos, Ioannis P.
Publicado 2019

Naringenin Ameliorates Drosophila ReepA Hereditary Spastic Paraplegia-Linked Phenotypes

por Napoli, Barbara, Gumeni, Sentiljana, Forgiarini, Alessia, Fantin, Marianna, De Filippis, Concetta, Panzeri, Elena, Vantaggiato, Chiara, Orso, Genny
Publicado 2019

Biological Evaluation and In Silico Study of Benzoic Acid Derivatives from Bjerkandera adusta Targeting Proteostasis Network Modules

por Georgousaki, Katerina, Tsafantakis, Nikolaos, Gumeni, Sentiljana, Lambrinidis, George, González-Menéndez, Victor, Tormo, Jose R., Genilloud, Olga, Trougakos, Ioannis P., Fokialakis, Nikolas
Publicado 2020

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy

por Tsakiri, Eleni N., Gumeni, Sentiljana, Vougas, Konstantinos, Pendin, Diana, Papassideri, Issidora, Daga, Andrea, Gorgoulis, Vassilis, Juhász, Gábor, Scorrano, Luca, Trougakos, Ioannis P.
Publicado 2019

Osmanicin, a Polyketide Alkaloid Isolated from Streptomyces osmaniensis CA-244599 Inhibits Elastase in Human Fibroblasts

por Samy, Mamdouh N., Le Goff, Géraldine, Lopes, Philippe, Georgousaki, Katerina, Gumeni, Sentiljana, Almeida, Celso, González, Ignacio, Genilloud, Olga, Trougakos, Ioannis, Fokialakis, Nikolas, Ouazzani, Jamal
Publicado 2019

Robust Neutralizing Antibody Responses 6 Months Post Vaccination with BNT162b2: A Prospective Study in 308 Healthy Individuals

por Terpos, Evangelos, Karalis, Vangelis, Ntanasis-Stathopoulos, Ioannis, Gavriatopoulou, Maria, Gumeni, Sentiljana, Malandrakis, Panagiotis, Papanagnou, Eleni-Dimitra, Kastritis, Efstathios, Trougakos, Ioannis P., Dimopoulos, Meletios A.
Publicado 2021

Longitudinal Analysis of Antibody Response Following SARS-CoV-2 Infection Depending on Disease Severity: A Prospective Cohort Study

por Zirou, Christina, Gumeni, Sentiljana, Bellos, Ioannis, Ntanasis-Stathopoulos, Ioannis, Sklirou, Aimilia D., Bagratuni, Tina, Korompoki, Eleni, Apostolakou, Filia, Papassotiriou, Ioannis, Trougakos, Ioannis P., Terpos, Evangelos
Publicado 2023

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation

por Tsakiri, Eleni N., Gumeni, Sentiljana, Iliaki, Kalliopi K., Benaki, Dimitra, Vougas, Konstantinos, Sykiotis, Gerasimos P., Gorgoulis, Vassilis G., Mikros, Emmanuel, Scorrano, Luca, Trougakos, Ioannis P.
Publicado 2018

Comoclathrin, a novel potent skin-whitening agent produced by endophytic Comoclathris strains associated with Andalusia desert plants

por Georgousaki, Katerina, González-Menéndez, Victor, Tormo, José R., Tsafantakis, Nikolaos, Mackenzie, Thomas A., Martín, Jesús, Gumeni, Sentiljana, Trougakos, Ioannis P., Reyes, Fernando, Fokialakis, Nikolas, Genilloud, Olga
Publicado 2022

Rescue of lysosomal function as therapeutic strategy for SPG15 hereditary spastic paraplegia

por Vantaggiato, Chiara, Orso, Genny, Guarato, Giulia, Brivio, Francesca, Napoli, Barbara, Panzeri, Elena, Masotti, Simona, Santorelli, Filippo Maria, Lamprou, Maria, Gumeni, Sentiljana, Clementi, Emilio, Bassi, Maria Teresa
Publicado 2022

Spastin Binds to Lipid Droplets and Affects Lipid Metabolism

por Papadopoulos, Chrisovalantis, Orso, Genny, Mancuso, Giuseppe, Herholz, Marija, Gumeni, Sentiljana, Tadepalle, Nimesha, Jüngst, Christian, Tzschichholz, Anne, Schauss, Astrid, Höning, Stefan, Trifunovic, Aleksandra, Daga, Andrea, Rugarli, Elena I.
Publicado 2015

Autophagy activation can partially rescue proteasome dysfunction‐mediated cardiac toxicity

por Papanagnou, Eleni‐Dimitra, Gumeni, Sentiljana, Sklirou, Aimilia D., Rafeletou, Alexandra, Terpos, Evangelos, Keklikoglou, Kleoniki, Kastritis, Efstathios, Stamatelopoulos, Kimon, Sykiotis, Gerasimos P., Dimopoulos, Meletios A., Trougakos, Ioannis P.
Publicado 2022