Activation of host transient receptor potential (TRP) channels by praziquantel stereoisomers

por Gunaratne, Gihan S., Yahya, Nawal A., Dosa, Peter I., Marchant, Jonathan S.
Publicado 2018

NAADP-dependent Ca(2+) signaling regulates Middle East respiratory syndrome-coronavirus pseudovirus translocation through the endolysosomal system

por Gunaratne, Gihan S., Yang, Yang, Li, Fang, Walseth, Timothy F., Marchant, Jonathan S.
Publicado 2018

A screening campaign in sea urchin egg homogenate as a platform for discovering modulators of NAADP-dependent Ca(2+) signaling in human cells

por Gunaratne, Gihan S., Johns, Malcolm E., Hintz, Hallie M., Walseth, Timothy F., Marchant, Jonathan S.
Publicado 2018

Electrophysiology of Endolysosomal Two-Pore Channels: A Current Account

por Patel, Sandip, Yuan, Yu, Chen, Cheng-Chang, Jaślan, Dawid, Gunaratne, Gihan, Grimm, Christian, Rahman, Taufiq, Marchant, Jonathan S.
Publicado 2022

Progesterone receptor membrane component 1 facilitates Ca(2+) signal amplification between endosomes and the endoplasmic reticulum

por Gunaratne, Gihan S., Kumar, Sushil, Lin-Moshier, Yaping, Slama, James T., Brailoiu, Eugen, Patel, Sandip, Walseth, Timothy F., Marchant, Jonathan S.
Publicado 2023

The anthelmintic drug praziquantel activates a schistosome transient receptor potential channel

por Park, Sang-Kyu, Gunaratne, Gihan S., Chulkov, Evgeny G., Moehring, Francie, McCusker, Paul, Dosa, Peter I., Chan, John D., Stucky, Cheryl L., Marchant, Jonathan S.
Publicado 2019

Identification of a dihydropyridine scaffold that blocks ryanodine receptors

por Gunaratne, Gihan S., Rebbeck, Robyn T., McGurran, Lindsey M., Yan, Yasheng, Arzua, Thiago, Frolkis, Talia, Sprague, Daniel J., Bai, Xiaowen, Cornea, Razvan L., Walseth, Timothy F., Marchant, Jonathan S.
Publicado 2021

The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

por Chan, John D., Cupit, Pauline M., Gunaratne, Gihan S., McCorvy, John D., Yang, Yang, Stoltz, Kristen, Webb, Thomas R., Dosa, Peter I., Roth, Bryan L., Abagyan, Ruben, Cunningham, Charles, Marchant, Jonathan S.
Publicado 2017

TMEM33 regulates intracellular calcium homeostasis in renal tubular epithelial cells

por Arhatte, Malika, Gunaratne, Gihan S., El Boustany, Charbel, Kuo, Ivana Y., Moro, Céline, Duprat, Fabrice, Plaisant, Magali, Duval, Hélène, Li, Dahui, Picard, Nicolas, Couvreux, Anais, Duranton, Christophe, Rubera, Isabelle, Pagnotta, Sophie, Lacas-Gervais, Sandra, Ehrlich, Barbara E., Marchant, Jonathan S., Savage, Aaron M., van Eeden, Fredericus J. M., Wilkinson, Robert N., Demolombe, Sophie, Honoré, Eric, Patel, Amanda
Publicado 2019

Mechanisms of SARS-CoV-2 neutralization by shark variable new antigen receptors elucidated through X-ray crystallography

por Ubah, Obinna C., Lake, Eric W., Gunaratne, Gihan S., Gallant, Joseph P., Fernie, Marie, Robertson, Austin J., Marchant, Jonathan S., Bold, Tyler D., Langlois, Ryan A., Matchett, William E., Thiede, Joshua M., Shi, Ke, Yin, Lulu, Moeller, Nicholas H., Banerjee, Surajit, Ferguson, Laura, Kovaleva, Marina, Porter, Andrew J., Aihara, Hideki, LeBeau, Aaron M., Barelle, Caroline J.
Publicado 2021