Modulator Therapy in Cystic Fibrosis Patients with cis Variants in F508del Complex Allele: A Short-Term Observational Case Series

por Terlizzi, Vito, Centrone, Claudia, Ferrari, Beatrice, Castellani, Chiara, Gunawardena, Tarini N. A., Taccetti, Giovanni, Laselva, Onofrio
Publicado 2022

Rescue of multiple class II CFTR mutations by elexacaftor+tezacaftor+ivacaftor mediated in part by the dual activities of elexacaftor as both corrector and potentiator

por Laselva, Onofrio, Bartlett, Claire, Gunawardena, Tarini N.A., Ouyang, Hong, Eckford, Paul D.W., Moraes, Theo J., Bear, Christine E., Gonska, Tanja
Publicado 2021

Correlation of Electrophysiological and Fluorescence-Based Measurements of Modulator Efficacy in Nasal Epithelial Cultures Derived from People with Cystic Fibrosis

por Gunawardena, Tarini N. A., Bozóky, Zoltán, Bartlett, Claire, Ouyang, Hong, Eckford, Paul D. W., Moraes, Theo J., Ratjen, Felix, Gonska, Tanja, Bear, Christine E.
Publicado 2023

The CFTR Mutation c.3453G > C (D1152H) Confers an Anion Selectivity Defect in Primary Airway Tissue that Can be Rescued by Ivacaftor

por Laselva, Onofrio, Moraes, Theo J., He, Gengming, Bartlett, Claire, Szàrics, Ida, Ouyang, Hong, Gunawardena, Tarini N. A., Strug, Lisa, Bear, Christine E., Gonska, Tanja
Publicado 2020

Preclinical Studies of a Rare CF-Causing Mutation in the Second Nucleotide Binding Domain (c.3700A>G) Show Robust Functional Rescue in Primary Nasal Cultures by Novel CFTR Modulato...

por Laselva, Onofrio, McCormack, Jacqueline, Bartlett, Claire, Ip, Wan, Gunawardena, Tarini N. A., Ouyang, Hong, Eckford, Paul D. W., Gonska, Tanja, Moraes, Theo J., Bear, Christine E.
Publicado 2020