Recurrent Rare Genomic Copy Number Variants and Bicuspid Aortic Valve Are Enriched in Early Onset Thoracic Aortic Aneurysms and Dissections

por Prakash, Siddharth, Kuang, Shao-Qing, Regalado, Ellen, Guo, Dongchuan, Milewicz, Dianna
Publicado 2016

Proteomic analysis of descending thoracic aorta identifies unique and universal signatures of aneurysm and dissection

por Saddic, Louis, Orosco, Amanda, Guo, Dongchuan, Milewicz, Dianna M., Troxlair, Dana, Heide, Richard Vander, Herrington, David, Wang, Yue, Azizzadeh, Ali, Parker, Sarah J.
Publicado 2022

Differentiation between Descending Thoracic Aortic Diseases using Machine Learning and Plasma Proteomic Signatures

por Momenzadeh, Amanda, Kreimer, Simion, Guo, Dongchuan, Ayres, Matthew, Berman, Daniel, Chyu, Kuang-Yuh, Shah, Prediman K, Milewicz, Dianna, Azizzadeh, Ali, Meyer, Jesse G., Parker, Sarah
Publicado 2023

Rare deleterious variants of NOTCH1, GATA4, SMAD6, and ROBO4 are enriched in BAV with early onset complications but not in BAV with heritable thoracic aortic disease

por Musfee, Fadi I., Guo, Dongchuan, Pinard, Amélie C., Hostetler, Ellen M., Blue, Elizabeth E., Nickerson, Deborah A., Bamshad, Michael J., Milewicz, Dianna M., Prakash, Siddharth K.
Publicado 2020

Germline variants in HEY2 functional domains lead to congenital heart defects and thoracic aortic aneurysms

por van Walree, Eva S., Dombrowsky, Gregor, Jansen, Iris E., Mirkov, Maša Umićević, Zwart, Rob, Ilgun, Aho, Guo, Dongchuan, Clur, Sally-Ann B., Amin, Ahmed S., Savage, Jeanne E., van der Wal, Allard C., Waisfisz, Quinten, Maugeri, Alessandra, Wilsdon, Anna, Bu’Lock, Frances A., Hurles, Matthew E., Dittrich, Sven, Berger, Felix, Martinez, Enrique Audain, Christoffels, Vincent M., Hitz, Marc-Philip, Milewicz, Dianna M., Posthuma, Daniëlle, Meijers-Heijboer, Hanne, Postma, Alex V., Mathijssen, Inge B.
Publicado 2021

Genome-wide analysis yields new loci associating with aortic valve stenosis

por Helgadottir, Anna, Thorleifsson, Gudmar, Gretarsdottir, Solveig, Stefansson, Olafur A., Tragante, Vinicius, Thorolfsdottir, Rosa B., Jonsdottir, Ingileif, Bjornsson, Thorsteinn, Steinthorsdottir, Valgerdur, Verweij, Niek, Nielsen, Jonas B., Zhou, Wei, Folkersen, Lasse, Martinsson, Andreas, Heydarpour, Mahyar, Prakash, Siddharth, Oskarsson, Gylfi, Gudbjartsson, Tomas, Geirsson, Arnar, Olafsson, Isleifur, Sigurdsson, Emil L., Almgren, Peter, Melander, Olle, Franco-Cereceda, Anders, Hamsten, Anders, Fritsche, Lars, Lin, Maoxuan, Yang, Bo, Hornsby, Whitney, Guo, Dongchuan, Brummett, Chad M., Abecasis, Gonçalo, Mathis, Michael, Milewicz, Dianna, Body, Simon C., Eriksson, Per, Willer, Cristen J., Hveem, Kristian, Newton-Cheh, Christopher, Smith, J. Gustav, Danielsen, Ragnar, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Holm, Hilma, Stefansson, Kari
Publicado 2018