Mitotic Accumulation of Dimethylated Lysine 79 of Histone H3 Is Important for Maintaining Genome Integrity During Mitosis in Human Cells

por Guppy, Brent J., McManus, Kirk J.
Publicado 2015

Synthetic Genetic Targeting of Genome Instability in Cancer

por Sajesh, Babu V., Guppy, Brent J., McManus, Kirk J.
Publicado 2013

Reduced USP22 Expression Impairs Mitotic Removal of H2B Monoubiquitination, Alters Chromatin Compaction and Induces Chromosome Instability That May Promote Oncogenesis

por Jeusset, Lucile M., Guppy, Brent J., Lichtensztejn, Zelda, McDonald, Darin, McManus, Kirk J.
Publicado 2021

An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

por van Pel, Derek M., Barrett, Irene J., Shimizu, Yoko, Sajesh, Babu V., Guppy, Brent J., Pfeifer, Tom, McManus, Kirk J., Hieter, Philip
Publicado 2013

Correction: An Evolutionarily Conserved Synthetic Lethal Interaction Network Identifies FEN1 as a Broad-Spectrum Target for Anticancer Therapeutic Development

por van Pel, Derek M., Barrett, Irene J., Shimizu, Yoko, Sajesh, Babu V., Guppy, Brent J., Pfeifer, Tom, McManus, Kirk J., Hieter, Philip
Publicado 2013

Combined MEK and JAK/STAT3 pathway inhibition effectively decreases SHH medulloblastoma tumor progression

por Zagozewski, Jamie, Borlase, Stephanie, Guppy, Brent J., Coudière-Morrison, Ludivine, Shahriary, Ghazaleh M., Gordon, Victor, Liang, Lisa, Cheng, Stephen, Porter, Christopher J., Kelley, Rhonda, Hawkins, Cynthia, Chan, Jennifer A., Liang, Yan, Gong, Jingjing, Nör, Carolina, Saulnier, Olivier, Wechsler-Reya, Robert J., Ramaswamy, Vijay, Werbowetski-Ogilvie, Tamra E.
Publicado 2022

A single nucleotide polymorphism assay sheds light on the extent and distribution of genetic diversity, population structure and functional basis of key traits in cultivated north...

por Henry, Philippe, Khatodia, Surender, Kapoor, Karan, Gonzales, Britni, Middleton, Alexis, Hong, Kevin, Hilyard, Aaron, Johnson, Steve, Allen, Davis, Chester, Zachary, Jin, Dan, Rodriguez Jule, José Carlos, Wilson, Iain, Gangola, Manu, Broome, Jason, Caplan, Deron, Adhikary, Dinesh, Deyholos, Michael K., Morgan, Michael, Hall, Oliver W., Guppy, Brent J., Orser, Cindy
Publicado 2020