Multiple myeloma in an Amur tiger (Panthera tigris altaica)

por Lee, Alison M., Guppy, Naomi, Bainbridge, John, Jahns, Hanne
Publicado 2017

Sox11 regulates mammary tumour-initiating and metastatic capacity in Brca1-deficient mouse mammary tumour cells

por Tsang, Siu Man, Kim, Hyojin, Oliemuller, Erik, Newman, Richard, Boateng, Naa-Anyima, Guppy, Naomi, Howard, Beatrice A.
Publicado 2021

Age-associated microenvironmental changes highlight the role of PDGF-C in ER(+) breast cancer metastatic relapse

por Turrell, Frances K., Orha, Rebecca, Guppy, Naomi J., Gillespie, Andrea, Guelbert, Matthew, Starling, Chris, Haider, Syed, Isacke, Clare M.
Publicado 2023

Tumor Necrosis Factor (TNF) Bioactivity at the Site of an Acute Cell-Mediated Immune Response Is Preserved in Rheumatoid Arthritis Patients Responding to Anti-TNF Therapy

por Byng-Maddick, Rachel, Turner, Carolin T., Pollara, Gabriele, Ellis, Matthew, Guppy, Naomi J., Bell, Lucy C. K., Ehrenstein, Michael R., Noursadeghi, Mahdad
Publicado 2017

Integrin α2β1 Expression Regulates Matrix Metalloproteinase-1-Dependent Bronchial Epithelial Repair in Pulmonary Tuberculosis

por Brilha, Sara, Chong, Deborah L. W., Khawaja, Akif A., Ong, Catherine W. M., Guppy, Naomi J., Porter, Joanna C., Friedland, Jon S.
Publicado 2018

Validation of Immune Cell Modules in Multicellular Transcriptomic Data

por Pollara, Gabriele, Murray, Matthew J., Heather, James M., Byng-Maddick, Rachel, Guppy, Naomi, Ellis, Matthew, Turner, Carolin T., Chain, Benjamin M., Noursadeghi, Mahdad
Publicado 2017

Rapid and complete paraffin removal from human tissue sections delivers enhanced Raman spectroscopic and histopathological analysis

por Gaifulina, Riana, Caruana, Daren J., Oukrif, Dahmane, Guppy, Naomi J., Culley, Siân, Brown, Robert, Bell, Ian, Rodriguez-Justo, Manuel, Lau, Katherine, Thomas, Geraint M. H.
Publicado 2020

The Impact of Diet‐Induced Weight Loss on Biomarkers for Colorectal Cancer: An Exploratory Study (INTERCEPT)

por Beeken, Rebecca J., Croker, Helen, Heinrich, Malgorzata, Obichere, Austin, Finer, Nicholas, Murphy, Neil, Goldin, Robert, Guppy, Naomi J., Wilson, Rose, Fisher, Abigail, Steptoe, Andrew, Gunter, Marc J., Wardle, Jane
Publicado 2017

Alternative tissue fixation for combined histopathological and molecular analysis in a clinically representative setting

por Meecham, Amelia, Miranda, Elena, Morris, Hayley T., Hair, Jane, Oien, Karin A., Gerrard, Gareth, Guppy, Naomi, Mooney, David, Shaw, Emily C., Ashton-Key, Margaret, Lees, Robert, Flanagan, Adrienne, Rodriguez-Justo, Manuel
Publicado 2021

Unmasking the immune microecology of ductal carcinoma in situ with deep learning

por Narayanan, Priya Lakshmi, Raza, Shan E. Ahmed, Hall, Allison H., Marks, Jeffrey R., King, Lorraine, West, Robert B., Hernandez, Lucia, Guppy, Naomi, Dowsett, Mitch, Gusterson, Barry, Maley, Carlo, Hwang, E. Shelley, Yuan, Yinyin
Publicado 2021

RIPK1‐mediated immunogenic cell death promotes anti‐tumour immunity against soft‐tissue sarcoma

por Smith, Henry G, Jamal, Kunzah, Dayal, Jasbani HS, Tenev, Tencho, Kyula‐Currie, Joan, Guppy, Naomi, Gazinska, Patrycja, Roulstone, Victoria, Liccardi, Gianmaria, Davies, Emma, Roxanis, Ioannis, Melcher, Alan A, Hayes, Andrew J, Inman, Gareth J, Harrington, Kevin J, Meier, Pascal
Publicado 2020

EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen

por Scheipl, Susanne, Barnard, Michelle, Cottone, Lucia, Jorgensen, Mette, Drewry, David H, Zuercher, William J, Turlais, Fabrice, Ye, Hongtao, Leite, Ana P, Smith, James A, Leithner, Andreas, Möller, Peter, Brüderlein, Silke, Guppy, Naomi, Amary, Fernanda, Tirabosco, Roberto, Strauss, Sandra J, Pillay, Nischalan, Flanagan, Adrienne M
Publicado 2016

Quantitative Assessment and Prognostic Associations of the Immune Landscape in Ovarian Clear Cell Carcinoma

por Khalique, Saira, Nash, Sarah, Mansfield, David, Wampfler, Julian, Attygale, Ayoma, Vroobel, Katherine, Kemp, Harriet, Buus, Richard, Cottom, Hannah, Roxanis, Ioannis, Jones, Thomas, von Loga, Katharina, Begum, Dipa, Guppy, Naomi, Ramagiri, Pradeep, Fenwick, Kerry, Matthews, Nik, Hubank, Michael J. F., Lord, Christopher J., Haider, Syed, Melcher, Alan, Banerjee, Susana, Natrajan, Rachael
Publicado 2021

ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response

por Nagarajan, Sankari, Rao, Shalini V., Sutton, Joseph, Cheeseman, Danya, Dunn, Shanade, Papachristou, Evangelia K., Prada, Jose-Enrique Gonzalez, Couturier, Dominique-Laurent, Kumar, Sanjeev, Kishore, Kamal, Chilamakuri, Chandra Sekhar Reddy, Glont, Silvia-Elena, Goode, Emily Archer, Brodie, Cara, Guppy, Naomi, Natrajan, Rachael, Bruna, Alejandra, Caldas, Carlos, Russell, Alasdair, Siersbæk, Rasmus, Yusa, Kosuke, Chernukhin, Igor, Carroll, Jason S.
Publicado 2020

Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells

por Kolluri, Krishna Kalyan, Alifrangis, Constantine, Kumar, Neelam, Ishii, Yuki, Price, Stacey, Michaut, Magali, Williams, Steven, Barthorpe, Syd, Lightfoot, Howard, Busacca, Sara, Sharkey, Annabel, Yuan, Zhenqiang, Sage, Elizabeth K, Vallath, Sabarinath, Le Quesne, John, Tice, David A, Alrifai, Doraid, von Karstedt, Sylvia, Montinaro, Antonella, Guppy, Naomi, Waller, David A, Nakas, Apostolos, Good, Robert, Holmes, Alan, Walczak, Henning, Fennell, Dean A, Garnett, Mathew, Iorio, Francesco, Wessels, Lodewyk, McDermott, Ultan, Janes, Samuel M
Publicado 2018

Ubiquitylation of MLKL at lysine 219 positively regulates necroptosis-induced tissue injury and pathogen clearance

por Garcia, Laura Ramos, Tenev, Tencho, Newman, Richard, Haich, Rachel O., Liccardi, Gianmaria, John, Sidonie Wicky, Annibaldi, Alessandro, Yu, Lu, Pardo, Mercedes, Young, Samuel N., Fitzgibbon, Cheree, Fernando, Winnie, Guppy, Naomi, Kim, Hyojin, Liang, Lung-Yu, Lucet, Isabelle S., Kueh, Andrew, Roxanis, Ioannis, Gazinska, Patrycja, Sims, Martin, Smyth, Tomoko, Ward, George, Bertin, John, Beal, Allison M., Geddes, Brad, Choudhary, Jyoti S., Murphy, James M., Aurelia Ball, K., Upton, Jason W., Meier, Pascal
Publicado 2021

SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response

por Bland, Philip, Saville, Harry, Wai, Patty T., Curnow, Lucinda, Muirhead, Gareth, Nieminuszczy, Jadwiga, Ravindran, Nivedita, John, Marie Beatrix, Hedayat, Somaieh, Barker, Holly E., Wright, James, Yu, Lu, Mavrommati, Ioanna, Read, Abigail, Peck, Barrie, Allen, Mark, Gazinska, Patrycja, Pemberton, Helen N., Gulati, Aditi, Nash, Sarah, Noor, Farzana, Guppy, Naomi, Roxanis, Ioannis, Pratt, Guy, Oldreive, Ceri, Stankovic, Tatjana, Barlow, Samantha, Kalirai, Helen, Coupland, Sarah E., Broderick, Ronan, Alsafadi, Samar, Houy, Alexandre, Stern, Marc-Henri, Pettit, Stephen, Choudhary, Jyoti S., Haider, Syed, Niedzwiedz, Wojciech, Lord, Christopher J., Natrajan, Rachael
Publicado 2023