Preclinical evaluation of the epithelial sodium channel inhibitor BI 1265162 for treatment of cystic fibrosis

por Nickolaus, Peter, Jung, Birgit, Sabater, Juan, Constant, Samuel, Gupta, Abhya
Publicado 2020

An innovative phase II trial to establish proof of efficacy and optimal dose of a new inhaled epithelial sodium channel inhibitor BI 1265162 in adults and adolescents with cystic f...

por Goss, Christopher H., Jain, Raksha, Seibold, Wolfgang, Picard, Anne-Caroline, Hsu, Ming-Chi, Gupta, Abhya, Fajac, Isabelle
Publicado 2020

An exploratory study investigating biomarkers associated with autoimmune pulmonary alveolar proteinosis (aPAP)

por Campo, Ilaria, Meloni, Federica, Gahlemann, Martina, Sauter, Wiebke, Ittrich, Carina, Schoelch, Corinna, Trapnell, Bruce C., Gupta, Abhya
Publicado 2022

Efficacy and safety of inhaled ENaC inhibitor BI 1265162 in patients with cystic fibrosis: BALANCE-CF 1, a randomised, phase II study

por Goss, Christopher H., Fajac, Isabelle, Jain, Raksha, Seibold, Wolfgang, Gupta, Abhya, Hsu, Ming-Chi, Sutharsan, Sivagurunathan, Davies, Jane C., Mall, Marcus A.
Publicado 2022

TRPC6 inhibitor (BI 764198) to reduce risk and severity of ARDS due to COVID-19: a phase II randomised controlled trial

por Ware, Lorraine B, Soleymanlou, Nima, McAuley, Danny Francis, Estrada, Vicente, Diaz, George A, Lacamera, Peter, Kaste, Renee, Choi, Wansuk, Gupta, Abhya, Welte, Tobias
Publicado 2023

Baseline characteristics from a 3-year longitudinal study to phenotype subjects with COPD: the FOOTPRINTS study

por Crapo, James D., Gupta, Abhya, Lynch, David A., Turner, Alice M., Mroz, Robert M., Janssens, Wim, Ludwig-Sengpiel, Andrea, Koegler, Harald, Eleftheraki, Anastasia, Risse, Frank, Diefenbach, Claudia
Publicado 2023

A Phase 2 randomised study to establish efficacy, safety and dosing of a novel oral cathepsin C inhibitor, BI 1291583, in adults with bronchiectasis: Airleaf

por Chalmers, James D., Gupta, Abhya, Chotirmall, Sanjay H., Armstrong, April, Eickholz, Peter, Hasegawa, Naoki, McShane, Pamela J., O'Donnell, Anne E., Shteinberg, Michal, Watz, Henrik, Eleftheraki, Anastasia, Diefenbach, Claudia, Sauter, Wiebke
Publicado 2023

FOOTPRINTS study protocol: rationale and methodology of a 3-year longitudinal observational study to phenotype patients with COPD

por Crapo, James, Gupta, Abhya, Lynch, David A, Vogel-Claussen, Jens, Watz, Henrik, Turner, Alice M, Mroz, Robert M, Janssens, Wim, Ludwig-Sengpiel, Andrea, Beck, Markus, Langellier, Bérengère, Ittrich, Carina, Risse, Frank, Diefenbach, Claudia
Publicado 2021