Polymerase θ inhibition steps on the cGAS pedal

por Smith, Chelsea M., Gupta, Gaorav P.
Publicado 2023

Advances in managing breast cancer: a clinical update

por Gucalp, Ayca, Gupta, Gaorav P., Pilewskie, Melissa L., Sutton, Elizabeth J., Norton, Larry
Publicado 2014

Cell composition inference and identification of layer-specific spatial transcriptional profiles with POLARIS

por Chen, Jiawen, Luo, Tianyou, Jiang, Minzhi, Liu, Jiandong, Gupta, Gaorav P., Li, Yun
Publicado 2023

Poly(ADP) ribose polymerase promotes DNA polymerase theta-mediated end joining by activation of end resection

por Luedeman, Megan E., Stroik, Susanna, Feng, Wanjuan, Luthman, Adam J., Gupta, Gaorav P., Ramsden, Dale A.
Publicado 2022

Tracking plasma DNA mutation dynamics in estrogen receptor positive metastatic breast cancer with dPCR-SEQ

por Kumar, Sunil, Lindsay, Daniel, Chen, Q. Brent, Garrett, Amy L., Tan, Xianming M., Anders, Carey K., Carey, Lisa A., Gupta, Gaorav P.
Publicado 2018

Immune-Mediated Effects of Microplanar Radiotherapy with a Small Animal Irradiator

por Bazyar, Soha, O’Brien, Edward Timothy, Benefield, Thad, Roberts, Victoria R., Kumar, Rashmi J., Gupta, Gaorav P., Zhou, Otto, Lee, Yueh Z.
Publicado 2021

Mechanistic basis for microhomology identification and genome scarring by polymerase theta

por Carvajal-Garcia, Juan, Cho, Jang-Eun, Carvajal-Garcia, Pablo, Feng, Wanjuan, Wood, Richard D., Sekelsky, Jeff, Gupta, Gaorav P., Roberts, Steven A., Ramsden, Dale A.
Publicado 2020

Marker-free quantification of repair pathway utilization at Cas9-induced double-strand breaks

por Feng, Wanjuan, Simpson, Dennis A, Cho, Jang-Eun, Carvajal-Garcia, Juan, Smith, Chelsea M, Headley, Kathryn M, Hathaway, Nate, Ramsden, Dale A, Gupta, Gaorav P
Publicado 2021

Evidence that the human cell cycle is a series of uncoupled, memoryless phases

por Chao, Hui Xiao, Fakhreddin, Randy I, Shimerov, Hristo K, Kedziora, Katarzyna M, Kumar, Rashmi J, Perez, Joanna, Limas, Juanita C, Grant, Gavin D, Cook, Jeanette Gowen, Gupta, Gaorav P, Purvis, Jeremy E
Publicado 2019

Genetic determinants of cellular addiction to DNA polymerase theta

por Feng, Wanjuan, Simpson, Dennis A., Carvajal-Garcia, Juan, Price, Brandon A., Kumar, Rashmi J., Mose, Lisle E., Wood, Richard D., Rashid, Naim, Purvis, Jeremy E., Parker, Joel S., Ramsden, Dale A., Gupta, Gaorav P.
Publicado 2019

RNA-Based Classification of Homologous Recombination Deficiency in Racially Diverse Patients with Breast Cancer

por Walens, Andrea, Van Alsten, Sarah C., Olsson, Linnea T., Smith, Markia A., Lockhart, Alex, Gao, Xiaohua, Hamilton, Alina M., Kirk, Erin L., Love, Michael I., Gupta, Gaorav P., Perou, Charles M., Vaziri, Cyrus, Hoadley, Katherine A., Troester, Melissa A.
Publicado 2022

Dual inhibition of DNA-PK and DNA polymerase theta overcomes radiation resistance induced by p53 deficiency

por Kumar, Rashmi J, Chao, Hui Xiao, Simpson, Dennis A, Feng, Wanjuan, Cho, Min-Guk, Roberts, Victoria R, Sullivan, Aurora R, Shah, Sonam J, Wozny, Anne-Sophie, Fagan-Solis, Katerina, Kumar, Sunil, Luthman, Adam, Ramsden, Dale A, Purvis, Jeremy E, Gupta, Gaorav P
Publicado 2020

Plasma Circulating Tumor HPV DNA for the Surveillance of Cancer Recurrence in HPV-Associated Oropharyngeal Cancer

por Chera, Bhishamjit S., Kumar, Sunil, Shen, Colette, Amdur, Robert, Dagan, Roi, Green, Rebecca, Goldman, Emily, Weiss, Jared, Grilley-Olson, Juneko, Patel, Shetal, Zanation, Adam, Hackman, Trevor, Blumberg, Jeff, Patel, Samip, Thorp, Brian, Weissler, Mark, Yarbrough, Wendell, Sheets, Nathan, Mendenhall, William, Tan, Xianming M., Gupta, Gaorav P.
Publicado 2020

Genetic separation of Brca1 functions reveal mutation-dependent Polθ vulnerabilities

por Krais, John J., Glass, David J., Chudoba, Ilse, Wang, Yifan, Feng, Wanjuan, Simpson, Dennis, Patel, Pooja, Liu, Zemin, Neumann-Domer, Ryan, Betsch, Robert G., Bernhardy, Andrea J., Bradbury, Alice M., Conger, Jason, Yueh, Wei-Ting, Nacson, Joseph, Pomerantz, Richard T., Gupta, Gaorav P., Testa, Joseph R., Johnson, Neil
Publicado 2023

BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance

por Nacson, Joseph, Krais, John J., Bernhardy, Andrea J., Clausen, Emma, Feng, Wanjuan, Wang, Yifan, Nicolas, Emmanuelle, Cai, Kathy Q., Tricarico, Rossella, Hua, Xiang, DiMarcantonio, Daniela, Martinez, Esteban, Zong, Dali, Handorf, Elizabeth A., Bellacosa, Alfonso, Testa, Joseph R., Nussenzweig, Andre, Gupta, Gaorav P., Sykes, Stephen M., Johnson, Neil
Publicado 2018

Tumor Cell Extrinsic Synaptogyrin 3 Expression as a Diagnostic and Prognostic Biomarker in Head and Neck Cancer

por Murphy, Ryan M., Tasoulas, Jason, Porrello, Alessandro, Carper, Miranda B., Tsai, Yi-Hsuan, Coffey, Alisha R., Kumar, Sunil, Zeng, Peter YF., Schrank, Travis P., Midkiff, Bentley R., Cohen, Stephanie, Salazar, Ashley H., Hayward, Michele C., Hayes, D. Neil, Olshan, Andrew, Gupta, Gaorav P., Nichols, Anthony C., Yarbrough, Wendell G., Pecot, Chad V., Amelio, Antonio L.
Publicado 2022

Targeting ESR1 mutation–induced transcriptional addiction in breast cancer with BET inhibition

por Udden, Sm N., Wang, Qian, Kumar, Sunil, Malladi, Venkat S., Wu, Shwu-Yuan, Wei, Shuguang, Posner, Bruce A., Geboers, Sophie, Williams, Noelle S., Liu, Yulun, Sharma, Jayesh K., Mani, Ram S., Malladi, Srinivas, Parra, Karla, Hofstad, Mia, Raj, Ganesh V., Larios, Jose M., Jagsi, Reshma, Wicha, Max S., Park, Ben Ho, Gupta, Gaorav P., Chinnaiyan, Arul M., Chiang, Cheng-Ming, Alluri, Prasanna G.
Publicado 2022

Molecular classification and biomarkers of clinical outcome in breast ductal carcinoma in situ: Analysis of TBCRC 038 and RAHBT cohorts

por Strand, Siri H., Rivero-Gutiérrez, Belén, Houlahan, Kathleen E., Seoane, Jose A., King, Lorraine M., Risom, Tyler, Simpson, Lunden A., Vennam, Sujay, Khan, Aziz, Cisneros, Luis, Hardman, Timothy, Harmon, Bryan, Couch, Fergus, Gallagher, Kristalyn, Kilgore, Mark, We, Shi, DeMichele, Angela, King, Tari, McAuliffe, Priscilla F., Nangia, Julie, Lee, Joanna, Tseng, Jennifer, Storniolo, Anna Maria, Thompson, Alastair M., Gupta, Gaorav P., Burns, Robyn, Veis, Deborah J., DeSchryver, Katherine, Zhu, Chunfang, Matusiak, Magdalena, Wang, Jason, Zhu, Shirley X., Tappenden, Jen, Ding, Daisy Yi, Zhang, Dadong, Luo, Jingqin, Jiang, Shu, Varma, Sushama, Anderson, Lauren, Straub, Cody, Srivastava, Sucheta, Curtis, Christina, Tibshirani, Rob, Angelo, Robert Michael, Hall, Allison, Owzar, Kouros, Polyak, Kornelia, Maley, Carlo, Marks, Jeffrey R., Colditz, Graham A., Shelley Hwang, E., West, Robert B.
Publicado 2023