Structural basis of cyclic oligoadenylate binding to the transcription factor Csa3 outlines cross talk between type III and type I CRISPR systems

por Xia, Pengjun, Dutta, Anirudha, Gupta, Kushol, Batish, Mona, Parashar, Vijay
Publicado 2022

Structural Properties of HIV Integrase·Lens Epithelium-derived Growth Factor Oligomers

por Gupta, Kushol, Diamond, Tracy, Hwang, Young, Bushman, Frederic, Van Duyne, Gregory D.
Publicado 2010

Coiled-coil interactions mediate serine integrase directionality

por Gupta, Kushol, Sharp, Robert, Yuan, Jimmy B., Li, Huiguang, Van Duyne, Gregory D.
Publicado 2017

Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states

por Maciunas, Lina J., Porter, Nadia, Lee, Paula J., Gupta, Kushol, Loll, Patrick J.
Publicado 2021

Requirements for catalysis in the Cre recombinase active site

por Gibb, Bryan, Gupta, Kushol, Ghosh, Kaushik, Sharp, Robert, Chen, James, Van Duyne, Gregory D.
Publicado 2010

Functional activity of the H3.3 histone chaperone complex HIRA requires trimerization of the HIRA subunit

por Ray-Gallet, Dominique, Ricketts, M. Daniel, Sato, Yukari, Gupta, Kushol, Boyarchuk, Ekaterina, Senda, Toshiya, Marmorstein, Ronen, Almouzni, Geneviève
Publicado 2018

Influence of the amino-terminal sequence on the structure and function of HIV integrase

por Eilers, Grant, Gupta, Kushol, Allen, Audrey, Zhou, Jeffrey, Hwang, Young, Cory, Michael B., Bushman, Frederic D., Van Duyne, Gregory
Publicado 2020

Structure of a HIV-1 IN-Allosteric inhibitor complex at 2.93 Å resolution: Routes to inhibitor optimization

por Eilers, Grant, Gupta, Kushol, Allen, Audrey, Montermoso, Saira, Murali, Hemma, Sharp, Robert, Hwang, Young, Bushman, Frederic D., Van Duyne, Gregory
Publicado 2023

Conserved Distal Loop Residues in the Hsp104 and ClpB Middle Domain Contact Nucleotide-binding Domain 2 and Enable Hsp70-dependent Protein Disaggregation

por DeSantis, Morgan E., Sweeny, Elizabeth A., Snead, David, Leung, Eunice H., Go, Michelle S., Gupta, Kushol, Wendler, Petra, Shorter, James
Publicado 2014

Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3

por Cupo, Ryan R., Rizo, Alexandrea N., Braun, Gabriel A., Tse, Eric, Chuang, Edward, Gupta, Kushol, Southworth, Daniel R., Shorter, James
Publicado 2022

The group II intron ribonucleoprotein precursor is a large, loosely packed structure

por Huang, Tao, Shaikh, Tanvir R., Gupta, Kushol, Contreras-Martin, Lydia M., Grassucci, Robert A., Van Duyne, Gregory D., Frank, Joachim, Belfort, Marlene
Publicado 2011

Quaternary arrangement of an active, native group II intron ribonucleoprotein complex revealed by small-angle X-ray scattering

por Gupta, Kushol, Contreras, Lydia M., Smith, Dorie, Qu, Guosheng, Huang, Tao, Spruce, Lynn A., Seeholzer, Steven H., Belfort, Marlene, Van Duyne, Gregory D.
Publicado 2014

Membrane Proteins Have Distinct Fast Internal Motion and Residual Conformational Entropy

por O'Brien, Evan S., Fuglestad, Brian, Lessen, Henry J., Stetz, Matthew A., Lin, Danny W., Marques, Bryan S., Gupta, Kushol, Fleming, Karen G., Wand, A. Joshua
Publicado 2020

Solution structure of the core SMN–Gemin2 complex

por Sarachan, Kathryn L., Valentine, Kathleen G., Gupta, Kushol, Moorman, Veronica R., Gledhill, John M., Bernens, Matthew, Tommos, Cecilia, Wand, A. Joshua, Van Duyne, Gregory D.
Publicado 2012

Recognition of the TDP-43 nuclear localization signal by importin α1/β

por Doll, Steven G., Meshkin, Hamed, Bryer, Alexander J., Li, Fenglin, Ko, Ying-Hui, Lokareddy, Ravi K., Gillilan, Richard E., Gupta, Kushol, Perilla, Juan R., Cingolani, Gino
Publicado 2022

Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer

por Gupta, Kushol, Wen, Ying, Ninan, Nisha S, Raimer, Amanda C, Sharp, Robert, Spring, Ashlyn M, Sarachan, Kathryn L, Johnson, Meghan C, Van Duyne, Gregory D, Matera, A Gregory
Publicado 2021

Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase

por Gupta, Kushol, Turkki, Vesa, Sherrill-Mix, Scott, Hwang, Young, Eilers, Grant, Taylor, Louis, McDanal, Charlene, Wang, Ping, Temelkoff, David, Nolte, Robert T., Velthuisen, Emile, Jeffrey, Jerry, Van Duyne, Gregory D., Bushman, Frederic D.
Publicado 2016

Self-oligomerization regulates stability of survival motor neuron protein isoforms by sequestering an SCF(Slmb) degron

por Gray, Kelsey M., Kaifer, Kevin A., Baillat, David, Wen, Ying, Bonacci, Thomas R., Ebert, Allison D., Raimer, Amanda C., Spring, Ashlyn M., Have, Sara ten, Glascock, Jacqueline J., Gupta, Kushol, Van Duyne, Gregory D., Emanuele, Michael J., Lamond, Angus I., Wagner, Eric J., Lorson, Christian L., Matera, A. Gregory
Publicado 2018