Quality by Design (QbD) and Design of Experiments (DOE) as a Strategy for Tuning Lipid Nanoparticle Formulations for RNA Delivery

por Gurba-Bryśkiewicz, Lidia, Maruszak, Wioleta, Smuga, Damian A., Dubiel, Krzysztof, Wieczorek, Maciej
Publicado 2023

The design of experiments (DoE) in optimization of an aerobic flow Pd-catalyzed oxidation of alcohol towards an important aldehyde precursor in the synthesis of phosphatidylinositi...

por Michałek, Stanisław, Gurba-Bryśkiewicz, Lidia, Maruszak, Wioleta, Zagozda, Marcin, Maj, Anna M., Ochal, Zbigniew, Dubiel, Krzysztof, Wieczorek, Maciej
Publicado 2022

Tuning the Biological Activity of PI3Kδ Inhibitor by the Introduction of a Fluorine Atom Using the Computational Workflow

por Pietruś, Wojciech, Stypik, Mariola, Zagozda, Marcin, Banach, Martyna, Gurba-Bryśkiewicz, Lidia, Maruszak, Wioleta, Leniak, Arkadiusz, Kurczab, Rafał, Ochal, Zbigniew, Dubiel, Krzysztof, Wieczorek, Maciej
Publicado 2023

Implementation of QbD Approach to the Development of Chromatographic Methods for the Determination of Complete Impurity Profile of Substance on the Preclinical and Clinical Step of...

por Gurba-Bryśkiewicz, Lidia, Dawid, Urszula, Smuga, Damian A., Maruszak, Wioleta, Delis, Monika, Szymczak, Krzysztof, Stypik, Bartosz, Moroz, Aleksandra, Błocka, Aleksandra, Mroczkiewicz, Michał, Dubiel, Krzysztof, Wieczorek, Maciej
Publicado 2022

Results from Genetic Studies in Patients Affected with Craniosynostosis: Clinical and Molecular Aspects

por Bukowska-Olech, Ewelina, Sowińska-Seidler, Anna, Larysz, Dawid, Gawliński, Paweł, Koczyk, Grzegorz, Popiel, Delfina, Gurba-Bryśkiewicz, Lidia, Materna-Kiryluk, Anna, Adamek, Zuzanna, Szczepankiewicz, Aleksandra, Dominiak, Paweł, Glista, Filip, Matuszewska, Karolina, Jamsheer, Aleksander
Publicado 2022

Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists

por Pankiewicz, Piotr, Szybiński, Marcin, Kisielewska, Katarzyna, Gołębiowski, Filip, Krzemiński, Patryk, Rutkowska-Włodarczyk, Izabela, Moszczyński-Pętkowski, Rafał, Gurba-Bryśkiewicz, Lidia, Delis, Monika, Mulewski, Krzysztof, Smuga, Damian, Dominowski, Jakub, Janusz, Artur, Górka, Michał, Abramski, Krzysztof, Napiórkowska, Agnieszka, Nowotny, Marcin, Dubiel, Krzysztof, Kalita, Katarzyna, Wieczorek, Maciej, Pieczykolan, Jerzy, Matłoka, Mikołaj
Publicado 2021

Design, Synthesis, and Development of Pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part II—Benzimidazole Derivatives

por Stypik, Mariola, Michałek, Stanisław, Orłowska, Nina, Zagozda, Marcin, Dziachan, Maciej, Banach, Martyna, Turowski, Paweł, Gunerka, Paweł, Zdżalik-Bielecka, Daria, Stańczak, Aleksandra, Kędzierska, Urszula, Mulewski, Krzysztof, Smuga, Damian, Maruszak, Wioleta, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Pietruś, Wojciech, Ochal, Zbigniew, Mach, Mateusz, Zygmunt, Beata, Pieczykolan, Jerzy, Dubiel, Krzysztof, Wieczorek, Maciej
Publicado 2022

Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I—Indole Derivatives

por Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Publicado 2022