Generating mouse models for biomedical research: technological advances

por Gurumurthy, Channabasavaiah B., Lloyd, Kevin C. Kent
Publicado 2019

Designing and generating a mouse model: frequently asked questions

por Gurumurthy, Channabasavaiah B., Saunders, Thomas L., Ohtsuka, Masato
Publicado 2021

Nucleic acids delivery methods for genome editing in zygotes and embryos: the old, the new, and the old-new

por Sato, Masahiro, Ohtsuka, Masato, Watanabe, Satoshi, Gurumurthy, Channabasavaiah B.
Publicado 2016

Insertion of sequences at the original provirus integration site of mouse ROSA26 locus using the CRISPR/Cas9 system

por Quadros, Rolen M., Harms, Donald W., Ohtsuka, Masato, Gurumurthy, Channabasavaiah B.
Publicado 2015

CRISPR/Cas9-based generation of knockdown mice by intronic insertion of artificial microRNA using longer single-stranded DNA

por Miura, Hiromi, Gurumurthy, Channabasavaiah B, Sato, Takehito, Sato, Masahiro, Ohtsuka, Masato
Publicado 2015

GONAD: Genome-editing via Oviductal Nucleic Acids Delivery system: a novel microinjection independent genome engineering method in mice

por Takahashi, Gou, Gurumurthy, Channabasavaiah B, Wada, Kenta, Miura, Hiromi, Sato, Masahiro, Ohtsuka, Masato
Publicado 2015

Precise and efficient nucleotide substitution near genomic nick via noncanonical homology-directed repair

por Nakajima, Kazuhiro, Zhou, Yue, Tomita, Akiko, Hirade, Yoshihiro, Gurumurthy, Channabasavaiah B., Nakada, Shinichiro
Publicado 2018

A transgenic pig model expressing a CMV-ZsGreen1 reporter across an extensive array of tissues

por Desaulniers, Amy T., Cederberg, Rebecca A., Carreiro, Elizabeth P., Gurumurthy, Channabasavaiah B., White, Brett R.
Publicado 2021

Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior

por Jung, Eui-Man, Moffat, Jeffrey Jay, Liu, Jinxu, Dravid, Shashank Manohar, Gurumurthy, Channabasavaiah, Kim, Woo-Yang
Publicado 2017

Generation of a Retinoblastoma (Rb)1-inducible dominant-negative (DN) mouse model

por Tarang, Shikha, Doi, Songila M. S. R., Gurumurthy, Channabasavaiah B., Harms, Donald, Quadros, Rolen, Rocha-Sanchez, Sonia M.
Publicado 2015

Assessment of Artificial MiRNA Architectures for Higher Knockdown Efficiencies without the Undesired Effects in Mice

por Miura, Hiromi, Inoko, Hidetoshi, Tanaka, Masafumi, Nakaoka, Hirofumi, Kimura, Minoru, Gurumurthy, Channabasavaiah B., Sato, Masahiro, Ohtsuka, Masato
Publicado 2015

Validation of Simple Sequence Length Polymorphism Regions of Commonly Used Mouse Strains for Marker Assisted Speed Congenics Screening

por Gurumurthy, Channabasavaiah B., Joshi, Poonam S., Kurz, Scott G., Ohtsuka, Masato, Quadros, Rolen M., Harms, Donald W., Lloyd, K. C. Kent
Publicado 2015

Ca(2+) sensor synaptotagmin-1 mediates exocytosis in mammalian photoreceptors

por Grassmeyer, Justin J, Cahill, Asia L, Hays, Cassandra L, Barta, Cody, Quadros, Rolen M, Gurumurthy, Channabasavaiah B, Thoreson, Wallace B
Publicado 2019

i-GONAD: a robust method for in situ germline genome engineering using CRISPR nucleases

por Ohtsuka, Masato, Sato, Masahiro, Miura, Hiromi, Takabayashi, Shuji, Matsuyama, Makoto, Koyano, Takayuki, Arifin, Naomi, Nakamura, Shingo, Wada, Kenta, Gurumurthy, Channabasavaiah B.
Publicado 2018

Nucleic Acid and Non-Nucleic Acid-Based Reprogramming of Adult Limbal Progenitors to Pluripotency

por Parameswaran, Sowmya, Balasubramanian, Sudha, Babai, Norbert, DelDebbio, Carolina B., Harms, Donald W., Gurumurthy, Channabasavaiah B., Rao, Mahendra S., Sharp, John G., Ahmad, Iqbal
Publicado 2012

Novel reporter mouse models useful for evaluating in vivo gene editing and for optimization of methods of delivering genome editing tools

por Miura, Hiromi, Imafuku, Jurai, Kurosaki, Aki, Sato, Masahiro, Ma, Yongjie, Zhang, Guisheng, Mizutani, Akiko, Kamimura, Kenya, Gurumurthy, Channabasavaiah B., Liu, Dexi, Ohtsuka, Masato
Publicado 2021

CRISPR-KRISPR: a method to identify on-target and random insertion of donor DNAs and their characterization in knock-in mice

por Tanaka, Masayuki, Yokoyama, Keiko, Hayashi, Hideki, Isaki, Sanae, Kitatani, Kanae, Wang, Ting, Kawata, Hisako, Matsuzawa, Hideyuki, Gurumurthy, Channabasavaiah B., Miura, Hiromi, Ohtsuka, Masato
Publicado 2022

Transgenic Mice Expressing Functional TCRs Specific to Cardiac Myhc-α 334–352 on Both CD4 and CD8 T Cells Are Resistant to the Development of Myocarditis on C57BL/6 Genetic Backgro...

por Sur, Meghna, Rasquinha, Mahima T., Arumugam, Rajkumar, Massilamany, Chandirasegaran, Gangaplara, Arunkumar, Mone, Kiruthiga, Lasrado, Ninaad, Yalaka, Bharathi, Doiphode, Aakash, Gurumurthy, Channabasavaiah, Steffen, David, Reddy, Jay
Publicado 2023

One-step generation of multiple transgenic mouse lines using an improved Pronuclear Injection-based Targeted Transgenesis (i-PITT)

por Ohtsuka, Masato, Miura, Hiromi, Mochida, Keiji, Hirose, Michiko, Hasegawa, Ayumi, Ogura, Atsuo, Mizutani, Ryuta, Kimura, Minoru, Isotani, Ayako, Ikawa, Masahito, Sato, Masahiro, Gurumurthy, Channabasavaiah B
Publicado 2015

An Atoh1 CRE Knock-In Mouse Labels Motor Neurons Involved in Fine Motor Control

por Ogujiofor, Osita W., Pop, Iliodora V., Espinosa, Felipe, Durodoye, Razaq O., Viacheslavov, Michael L., Jarvis, Rachel, Landy, Mark A., Gurumurthy, Channabasavaiah B., Lai, Helen C.
Publicado 2021