JunB Inhibits ER Stress and Apoptosis in Pancreatic Beta Cells

por Gurzov, Esteban N., Ortis, Fernanda, Bakiri, Latifa, Wagner, Erwin F., Eizirik, Decio L.
Publicado 2008

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic β-cell responses to the viral by-product double-stranded RNA

por Colli, Maikel L., Moore, Fabrice, Gurzov, Esteban N., Ortis, Fernanda, Eizirik, Decio L.
Publicado 2010

Paradoxical antiproliferative effect by a murine mammary tumor-derived epithelial cell line

por Gurzov, Esteban N, Nabha, Sanaa M, Yamamoto, Hamilto, Meng, Hong, Scharovsky, O Graciela, Bonfil, R Daniel
Publicado 2007

Non-alcoholic fatty liver disease and diabetes mellitus as growing aetiologies of hepatocellular carcinoma

por Talamantes, Stephanie, Lisjak, Michela, Gilglioni, Eduardo H., Llamoza-Torres, Camilo J., Ramos-Molina, Bruno, Gurzov, Esteban N.
Publicado 2023

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Pancreatic β-Cell Apoptosis via Regulation of the BH3-Only Protein Bim

por Santin, Izortze, Moore, Fabrice, Colli, Maikel L., Gurzov, Esteban N., Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L.
Publicado 2011

The Transcription Factor C/EBP delta Has Anti-Apoptotic and Anti-Inflammatory Roles in Pancreatic Beta Cells

por Moore, Fabrice, Santin, Izortze, Nogueira, Tatiane C., Gurzov, Esteban N., Marselli, Lorella, Marchetti, Piero, Eizirik, Decio L.
Publicado 2012

Activation of the NLRP3 Inflammasome Complex is Not Required for Stress-Induced Death of Pancreatic Islets

por Wali, Jibran A., Gurzov, Esteban N., Fynch, Stacey, Elkerbout, Lorraine, Kay, Thomas W., Masters, Seth L., Thomas, Helen E.
Publicado 2014

Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice

por Brahma, Manoja K., Xiao, Peng, Popa, Madalina, Negueruela, Javier, Vandenbempt, Valerie, Demine, Stéphane, Cardozo, Alessandra K., Gurzov, Esteban N.
Publicado 2022

Pancreatic β-Cell Membrane Fluidity and Toxicity Induced by Human Islet Amyloid Polypeptide Species

por Pilkington, Emily H., Gurzov, Esteban N., Kakinen, Aleksandr, Litwak, Sara A., Stanley, William J., Davis, Thomas P., Ke, Pu Chun
Publicado 2016

Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation

por Takiishi, Tatiana, Xiao, Peng, Franchimont, Marie, Gilglioni, Eduardo H., Arroba, Erick N., Gurzov, Esteban N., Bertrand, Mathieu JM., Cardozo, Alessandra K.
Publicado 2023

Glucagon-Like Peptide-1 Agonists Protect Pancreatic β-Cells From Lipotoxic Endoplasmic Reticulum Stress Through Upregulation of BiP and JunB

por Cunha, Daniel A., Ladrière, Laurence, Ortis, Fernanda, Igoillo-Esteve, Mariana, Gurzov, Esteban N., Lupi, Roberto, Marchetti, Piero, Eizirik, Décio L., Cnop, Miriam
Publicado 2009

p53-upregulated-modulator-of-apoptosis (PUMA) deficiency affects food intake but does not impact on body weight or glucose homeostasis in diet-induced obesity.

por Litwak, Sara A., Loh, Kim, Stanley, William J., Pappas, Evan G., Wali, Jibran A., Selck, Claudia, Strasser, Andreas, Thomas, Helen E., Gurzov, Esteban N.
Publicado 2016

Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

por Colli, Maikel L., Nogueira, Tatiane C., Allagnat, Florent, Cunha, Daniel A., Gurzov, Esteban N., Cardozo, Alessandra K., Roivainen, Merja, Op de beeck, Anne, Eizirik, Decio L.
Publicado 2011

Lipotoxic Stress Induces Pancreatic β-Cell Apoptosis through Modulation of Bcl-2 Proteins by the Ubiquitin-Proteasome System

por Litwak, Sara A., Wali, Jibran A., Pappas, Evan G., Saadi, Hamdi, Stanley, William J., Varanasi, L. Chitra, Kay, Thomas W. H., Thomas, Helen E., Gurzov, Esteban N.
Publicado 2015

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated β-Cell Death

por Arif, Sefina, Moore, Fabrice, Marks, Katherine, Bouckenooghe, Thomas, Dayan, Colin M., Planas, Raquel, Vives-Pi, Marta, Powrie, Jake, Tree, Timothy, Marchetti, Piero, Huang, Guo Cai, Gurzov, Esteban N., Pujol-Borrell, Ricardo, Eizirik, Decio L., Peakman, Mark
Publicado 2011

Star Polymers Reduce Islet Amyloid Polypeptide Toxicity via Accelerated Amyloid Aggregation

por Pilkington, Emily H., Lai, May, Ge, Xinwei, Stanley, William J., Wang, Bo, Wang, Miaoyi, Kakinen, Aleksandr, Sani, Marc-Antonie, Whittaker, Michael R., Gurzov, Esteban N., Ding, Feng, Quinn, John F., Davis, Thomas P., Ke, Pu Chun
Publicado 2017

Death Protein 5 and p53-Upregulated Modulator of Apoptosis Mediate the Endoplasmic Reticulum Stress–Mitochondrial Dialog Triggering Lipotoxic Rodent and Human β-Cell Apoptosis

por Cunha, Daniel A., Igoillo-Esteve, Mariana, Gurzov, Esteban N., Germano, Carla M., Naamane, Najib, Marhfour, Ihsane, Fukaya, Makiko, Vanderwinden, Jean-Marie, Gysemans, Conny, Mathieu, Chantal, Marselli, Lorella, Marchetti, Piero, Harding, Heather P., Ron, David, Eizirik, Décio L., Cnop, Miriam
Publicado 2012

Inhibition of Y1 receptor signaling improves islet transplant outcome

por Loh, Kim, Shi, Yan-Chuan, Walters, Stacey, Bensellam, Mohammed, Lee, Kailun, Dezaki, Katsuya, Nakata, Masanori, Ip, Chi Kin, Chan, Jeng Yie, Gurzov, Esteban N., Thomas, Helen E., Waibel, Michaela, Cantley, James, Kay, Thomas W., Yada, Toshihiko, Laybutt, D. Ross, Grey, Shane T., Herzog, Herbert
Publicado 2017

Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

por Grohmann, Marcus, Wiede, Florian, Dodd, Garron T., Gurzov, Esteban N., Ooi, Geraldine J., Butt, Tariq, Rasmiena, Aliki A., Kaur, Supreet, Gulati, Twishi, Goh, Pei K., Treloar, Aislinn E., Archer, Stuart, Brown, Wendy A., Muller, Mathias, Watt, Matthew J., Ohara, Osamu, McLean, Catriona A., Tiganis, Tony
Publicado 2018

Metabolite-based dietary supplementation in human type 1 diabetes is associated with microbiota and immune modulation

por Bell, Kirstine J., Saad, Sonia, Tillett, Bree J., McGuire, Helen M., Bordbar, Sara, Yap, Yu Anne, Nguyen, Long T., Wilkins, Marc R., Corley, Susan, Brodie, Shannon, Duong, Sussan, Wright, Courtney J., Twigg, Stephen, de St Groth, Barbara Fazekas, Harrison, Leonard C., Mackay, Charles R., Gurzov, Esteban N., Hamilton-Williams, Emma E., Mariño, Eliana
Publicado 2022