Incorporating Machine Learning into Established Bioinformatics Frameworks

por Auslander, Noam, Gussow, Ayal B., Koonin, Eugene V.
Publicado 2021

Identification of combinations of somatic mutations that predict cancer survival and immunotherapy benefit

por Gussow, Ayal B, Koonin, Eugene V, Auslander, Noam
Publicado 2021

Prediction of the incubation period for COVID-19 and future virus disease outbreaks

por Gussow, Ayal B., Auslander, Noam, Wolf, Yuri I., Koonin, Eugene V.
Publicado 2020

Prioritizing non-coding regions based on human genomic constraint and sequence context with deep learning

por Vitsios, Dimitrios, Dhindsa, Ryan S., Middleton, Lawrence, Gussow, Ayal B., Petrovski, Slavé
Publicado 2021

The intolerance to functional genetic variation of protein domains predicts the localization of pathogenic mutations within genes

por Gussow, Ayal B., Petrovski, Slavé, Wang, Quanli, Allen, Andrew S., Goldstein, David B.
Publicado 2016

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

por Gussow, Ayal B., Auslander, Noam, Faure, Guilhem, Wolf, Yuri I., Zhang, Feng, Koonin, Eugene V.
Publicado 2020

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses

por Gussow, Ayal B., Auslander, Noam, Faure, Guilhem, Wolf, Yuri I., Zhang, Feng, Koonin, Eugene V.
Publicado 2020

Discovery of an expansive bacteriophage family that includes the most abundant viruses from the human gut

por Yutin, Natalya, Makarova, Kira S., Gussow, Ayal B., Krupovic, Mart, Segall, Anca, Edwards, Robert A., Koonin, Eugene V.
Publicado 2017

Thousands of previously unknown phages discovered in whole-community human gut metagenomes

por Benler, Sean, Yutin, Natalya, Antipov, Dmitry, Rayko, Mikhail, Shmakov, Sergey, Gussow, Ayal B., Pevzner, Pavel, Koonin, Eugene V.
Publicado 2021

The Intolerance of Regulatory Sequence to Genetic Variation Predicts Gene Dosage Sensitivity

por Petrovski, Slavé, Gussow, Ayal B., Wang, Quanli, Halvorsen, Matt, Han, Yujun, Weir, William H., Allen, Andrew S., Goldstein, David B.
Publicado 2015

Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

por Gussow, Ayal B., Copeland, Brett R., Dhindsa, Ryan S., Wang, Quanli, Petrovski, Slavé, Majoros, William H., Allen, Andrew S., Goldstein, David B.
Publicado 2017

Correction: Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics

por Gussow, Ayal B., Copeland, Brett R., Dhindsa, Ryan S., Wang, Quanli, Petrovski, Slavé, Majoros, William H., Allen, Andrew S., Goldstein, David B.
Publicado 2018

Machine-learning approach expands the repertoire of anti-CRISPR protein families

por Gussow, Ayal B., Park, Allyson E., Borges, Adair L., Shmakov, Sergey A., Makarova, Kira S., Wolf, Yuri I., Bondy-Denomy, Joseph, Koonin, Eugene V.
Publicado 2020

Inhibition of microRNA 128 promotes excitability of cultured cortical neuronal networks

por McSweeney, K. Melodi, Gussow, Ayal B., Bradrick, Shelton S., Dugger, Sarah A., Gelfman, Sahar, Wang, Quanli, Petrovski, Slavé, Frankel, Wayne N., Boland, Michael J., Goldstein, David B.
Publicado 2016