The methylome of the marbled crayfish links gene body methylation to stable expression of poorly accessible genes

por Gatzmann, Fanny, Falckenhayn, Cassandra, Gutekunst, Julian, Hanna, Katharina, Raddatz, Günter, Carneiro, Vitor Coutinho, Lyko, Frank
Publicado 2018

mIDH-associated DNA hypermethylation in acute myeloid leukemia reflects differentiation blockage rather than inhibition of TET-mediated demethylation

por Wiehle, Laura, Raddatz, Günter, Pusch, Stefan, Gutekunst, Julian, von Deimling, Andreas, Rodríguez-Paredes, Manuel, Lyko, Frank
Publicado 2017

Phylogeographic reconstruction of the marbled crayfish origin

por Gutekunst, Julian, Maiakovska, Olena, Hanna, Katharina, Provataris, Panagiotis, Horn, Hannes, Wolf, Stephan, Skelton, Christopher E., Dorn, Nathan J., Lyko, Frank
Publicado 2021

Epigenetic deregulation of lamina-associated domains in Hutchinson-Gilford progeria syndrome

por Köhler, Florian, Bormann, Felix, Raddatz, Günter, Gutekunst, Julian, Corless, Samuel, Musch, Tanja, Lonsdorf, Anke S., Erhardt, Sylvia, Lyko, Frank, Rodríguez-Paredes, Manuel
Publicado 2020

Transforming growth factor β1-mediated functional inhibition of mesenchymal stromal cells in myelodysplastic syndromes and acute myeloid leukemia

por Geyh, Stefanie, Rodríguez-Paredes, Manuel, Jäger, Paul, Koch, Annemarie, Bormann, Felix, Gutekunst, Julian, Zilkens, Christoph, Germing, Ulrich, Kobbe, Guido, Lyko, Frank, Haas, Rainer, Schroeder, Thomas
Publicado 2018

Reduced DNA methylation patterning and transcriptional connectivity define human skin aging

por Bormann, Felix, Rodríguez‐Paredes, Manuel, Hagemann, Sabine, Manchanda, Himanshu, Kristof, Boris, Gutekunst, Julian, Raddatz, Günter, Haas, Rainer, Terstegen, Lara, Wenck, Horst, Kaderali, Lars, Winnefeld, Marc, Lyko, Frank
Publicado 2016

Differentiation‐related epigenomic changes define clinically distinct keratinocyte cancer subclasses

por Solé‐Boldo, Llorenç, Raddatz, Günter, Gutekunst, Julian, Gilliam, Oliver, Bormann, Felix, Liberio, Michelle S, Hasche, Daniel, Antonopoulos, Wiebke, Mallm, Jan‐Philipp, Lonsdorf, Anke S, Rodríguez‐Paredes, Manuel, Lyko, Frank
Publicado 2022

Genome analysis of the monoclonal marbled crayfish reveals genetic separation over a short evolutionary timescale

por Maiakovska, Olena, Andriantsoa, Ranja, Tönges, Sina, Legrand, Carine, Gutekunst, Julian, Hanna, Katharina, Pârvulescu, Lucian, Novitsky, Roman, Weiperth, András, Sciberras, Arnold, Deidun, Alan, Ercoli, Fabio, Kouba, Antonin, Lyko, Frank
Publicado 2021

Impact of DLK1-DIO3 imprinted cluster hypomethylation in smoker patients with lung cancer

por Molina-Pinelo, Sonia, Salinas, Ana, Moreno-Mata, Nicolás, Ferrer, Irene, Suarez, Rocío, Andrés-León, Eduardo, Rodríguez-Paredes, Manuel, Gutekunst, Julian, Jantus-Lewintre, Eloisa, Camps, Carlos, Carnero, Amancio, Paz-Ares, Luis
Publicado 2016

TET2 and TET3 loss disrupts small intestine differentiation and homeostasis

por Ansari, Ihab, Solé-Boldo, Llorenç, Ridnik, Meshi, Gutekunst, Julian, Gilliam, Oliver, Korshko, Maria, Liwinski, Timur, Jickeli, Birgit, Weinberg-Corem, Noa, Shoshkes-Carmel, Michal, Pikarsky, Eli, Elinav, Eran, Lyko, Frank, Bergman, Yehudit
Publicado 2023

Methylation profiling identifies two subclasses of squamous cell carcinoma related to distinct cells of origin

por Rodríguez-Paredes, Manuel, Bormann, Felix, Raddatz, Günter, Gutekunst, Julian, Lucena-Porcel, Carlota, Köhler, Florian, Wurzer, Elisabeth, Schmidt, Katrin, Gallinat, Stefan, Wenck, Horst, Röwert-Huber, Joachim, Denisova, Evgeniya, Feuerbach, Lars, Park, Jeongbin, Brors, Benedikt, Herpel, Esther, Nindl, Ingo, Hofmann, Thomas G., Winnefeld, Marc, Lyko, Frank
Publicado 2018