The protective mutation A673T in amyloid precursor protein gene decreases Aβ peptides production for 14 forms of Familial Alzheimer’s Disease in SH-SY5Y cells

por Guyon, Antoine, Rousseau, Joël, Lamothe, Gabriel, Tremblay, Jacques P.
Publicado 2020

Insertion of the protective APP A673T mutation by CRISPR/Cas9 base editing or PRIME editing.

por Tremblay, Jacques, Guyon, Antoine, Rousseau, Joël, Tremblay, Guillaume, Begin, Francis-Gabriel, Lamothe, Gabriel
Publicado 2021

Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro

por Guyon, Antoine, Rousseau, Joël, Bégin, Francis-Gabriel, Bertin, Tom, Lamothe, Gabriel, Tremblay, Jacques P.
Publicado 2021