Invited Perspective: Prioritizing Chemical Testing and Evaluation Using Validated in Vitro Assays Relevant to Key Characteristics

por Guyton, Kathryn Z., Schubauer-Berigan, Mary K.
Publicado 2021

Approaches to Human Health Risk Assessment Based on the Signal-To-Noise Crossover Dose

por Chiu, Weihsueh A., Guyton, Kathryn Z., Hogan, Karen, Jinot, Jennifer
Publicado 2012

Prioritizing Chemicals for Risk Assessment Using Chemoinformatics: Examples from the IARC Monographs on Pesticides

por Guha, Neela, Guyton, Kathryn Z., Loomis, Dana, Barupal, Dinesh Kumar
Publicado 2016

Classification schemes for carcinogenicity based on hazard identification serve science and society

por Loomis, Dana, Guyton, Kathryn Z., Straif, Kurt, Wild, Christopher P.
Publicado 2017

Prioritizing cancer hazard assessments for IARC Monographs using an integrated approach of database fusion and text mining

por Barupal, Dinesh Kumar, Schubauer-Berigan, Mary K., Korenjak, Michael, Zavadil, Jiri, Guyton, Kathryn Z.
Publicado 2021

Addressing Human Variability in Next-Generation Human Health Risk Assessments of Environmental Chemicals

por Zeise, Lauren, Bois, Frederic Y., Chiu, Weihsueh A., Hattis, Dale, Rusyn, Ivan, Guyton, Kathryn Z.
Publicado 2012

Moving forward in carcinogenicity assessment: Report of an EURL ECVAM/ESTIV workshop

por Corvi, Raffaella, Madia, Federica, Guyton, Kathryn Z., Kasper, Peter, Rudel, Ruthann, Colacci, Annamaria, Kleinjans, Jos, Jennings, Paul
Publicado 2017

Conditional Toxicity Value (CTV) Predictor: An In Silico Approach for Generating Quantitative Risk Estimates for Chemicals

por Wignall, Jessica A., Muratov, Eugene, Sedykh, Alexander, Guyton, Kathryn Z., Tropsha, Alexander, Rusyn, Ivan, Chiu, Weihsueh A.
Publicado 2018

Research Recommendations for Selected IARC-Classified Agents: Impact and Lessons Learned

por Turner, Michelle C., Cogliano, Vincent, Guyton, Kathryn, Madia, Federica, Straif, Kurt, Ward, Elizabeth M., Schubauer-Berigan, Mary K.
Publicado 2023

A Reexamination of the PPAR-α Activation Mode of Action as a Basis for Assessing Human Cancer Risks of Environmental Contaminants

por Guyton, Kathryn Z., Chiu, Weihsueh A., Bateson, Thomas F., Jinot, Jennifer, Scott, Cheryl Siegel, Brown, Rebecca C., Caldwell, Jane C.
Publicado 2009

Standardizing Benchmark Dose Calculations to Improve Science-Based Decisions in Human Health Assessments

por Wignall, Jessica A., Shapiro, Andrew J., Wright, Fred A., Woodruff, Tracey J., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan
Publicado 2014

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse

por Chiu, Weihsueh A., Campbell, Jerry L., Clewell, Harvey J., Zhou, Yi-Hui, Wright, Fred A., Guyton, Kathryn Z., Rusyn, Ivan
Publicado 2014

Application of the key characteristics of carcinogens in cancer hazard identification

por Guyton, Kathryn Z, Rusyn, Ivan, Chiu, Weihsueh A, Corpet, Denis E, van den Berg, Martin, Ross, Matthew K, Christiani, David C, Beland, Frederick A, Smith, Martyn T
Publicado 2018

Re: ‘Application of the key characteristics of carcinogens in cancer hazard evaluation’: response to Goodman, Lynch and Rhomberg

por Guyton, Kathryn Z, Rusyn, Ivan, Chiu, Weihsueh A, Corpet, Denis E, van den Berg, Martin, Ross, Matthew K, Christiani, David C, Beland, Frederick A, Smith, Martyn T
Publicado 2018

Software Tools to Facilitate Systematic Review Used for Cancer Hazard Identification

por Shapiro, Andrew J., Antoni, Sébastien, Guyton, Kathryn Z., Lunn, Ruth M., Loomis, Dana, Rusyn, Ivan, Jahnke, Gloria D., Schwingl, Pamela J., Mehta, Suril S., Addington, Josh, Guha, Neela
Publicado 2018

Characterization of Changes in Gene Expression and Biochemical Pathways at Low Levels of Benzene Exposure

por Thomas, Reuben, Hubbard, Alan E., McHale, Cliona M., Zhang, Luoping, Rappaport, Stephen M., Lan, Qing, Rothman, Nathaniel, Vermeulen, Roel, Guyton, Kathryn Z., Jinot, Jennifer, Sonawane, Babasaheb R., Smith, Martyn T.
Publicado 2014

Human Health Effects of Tetrachloroethylene: Key Findings and Scientific Issues

por Guyton, Kathryn Z., Hogan, Karen A., Scott, Cheryl Siegel, Cooper, Glinda S., Bale, Ambuja S., Kopylev, Leonid, Barone, Stanley, Makris, Susan L., Glenn, Barbara, Subramaniam, Ravi P., Gwinn, Maureen R., Dzubow, Rebecca C., Chiu, Weihsueh A.
Publicado 2014

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

por La Merrill, Michele A., Vandenberg, Laura N., Smith, Martyn T., Goodson, William, Browne, Patience, Patisaul, Heather B., Guyton, Kathryn Z., Kortenkamp, Andreas, Cogliano, Vincent J., Woodruff, Tracey J., Rieswijk, Linda, Sone, Hideko, Korach, Kenneth S., Gore, Andrea C., Zeise, Lauren, Zoeller, R. Thomas
Publicado 2019

Human Health Effects of Trichloroethylene: Key Findings and Scientific Issues

por Chiu, Weihsueh A., Jinot, Jennifer, Scott, Cheryl Siegel, Makris, Susan L., Cooper, Glinda S., Dzubow, Rebecca C., Bale, Ambuja S., Evans, Marina V., Guyton, Kathryn Z., Keshava, Nagalakshmi, Lipscomb, John C., Barone, Stanley, Fox, John F., Gwinn, Maureen R., Schaum, John, Caldwell, Jane C.
Publicado 2012

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis

por Smith, Martyn T., Guyton, Kathryn Z., Gibbons, Catherine F., Fritz, Jason M., Portier, Christopher J., Rusyn, Ivan, DeMarini, David M., Caldwell, Jane C., Kavlock, Robert J., Lambert, Paul F., Hecht, Stephen S., Bucher, John R., Stewart, Bernard W., Baan, Robert A., Cogliano, Vincent J., Straif, Kurt
Publicado 2015