Synthesis of Conformationally Constrained d-Glu-meso-DAP Analogs as Innate Immune Agonists

por Guzelj, Samo, Jakopin, Žiga
Publicado 2020

Nucleotide-Binding Oligomerization Domain 1/Toll-Like Receptor 4 Co-Engagement Promotes Non-Specific Immune Response Against K562 Cancer Cells

por Guzelj, Samo, Jakopin, Žiga
Publicado 2022

Discovery of Desmuramylpeptide NOD2 Agonists with Single-Digit Nanomolar Potency

por Guzelj, Samo, Bizjak, Špela, Jakopin, Žiga
Publicado 2022

Novel Scaffolds for Modulation of NOD2 Identified by Pharmacophore-Based Virtual Screening

por Guzelj, Samo, Tomašič, Tihomir, Jakopin, Žiga
Publicado 2022

Covalently Conjugated NOD2/TLR7 Agonists Are Potent and Versatile Immune Potentiators

por Guzelj, Samo, Weiss, Matjaž, Slütter, Bram, Frkanec, Ruža, Jakopin, Žiga
Publicado 2022

Lipidation of NOD2 Agonists with Adamantane and Stearoyl Moieties Differentially Regulates Their In Vivo Adjuvant Activity

por Guzelj, Samo, Šišić, Marcela, Bizjak, Špela, Frkanec, Leo, Frkanec, Ruža, Jakopin, Žiga
Publicado 2022

Structure-Guided Design of d-Galactal Derivatives with High Affinity and Selectivity for the Galectin-8 N-Terminal Domain

por Hassan, Mujtaba, Baussière, Floriane, Guzelj, Samo, Sundin, Anders P., Håkansson, Maria, Kovačič, Rebeka, Leffler, Hakon, Tomašič, Tihomir, Anderluh, Marko, Jakopin, Žiga, Nilsson, Ulf J.
Publicado 2021

Structural Fine-Tuning of Desmuramylpeptide NOD2 Agonists Defines Their In Vivo Adjuvant Activity

por Guzelj, Samo, Nabergoj, Sanja, Gobec, Martina, Pajk, Stane, Klančič, Veronika, Slütter, Bram, Frkanec, Ruža, Štimac, Adela, Šket, Primož, Plavec, Janez, Mlinarič-Raščan, Irena, Jakopin, Žiga
Publicado 2021