HSP70-based anti-cancer immunotherapy

por Guzhova, Irina V., Margulis, Boris A.
Publicado 2016

Molecular Chaperones and Proteolytic Machineries Regulate Protein Homeostasis in Aging Cells

por Margulis, Boris, Tsimokha, Anna, Zubova, Svetlana, Guzhova, Irina
Publicado 2020

Glyceraldehyde-3-phosphate Dehydrogenase Is a Multifaceted Therapeutic Target

por Lazarev, Vladimir F., Guzhova, Irina V., Margulis, Boris A.
Publicado 2020

Phospholipse c inhibitor, u73122, stimulates release of hsp-70 stress protein from A431 human carcinoma cells

por Evdonin, Anton L, Guzhova, Irina V, Margulis, Boris A, Medvedeva, Natalia D
Publicado 2004

Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

por Lazarev, Vladimir F., Mikhaylova, Elena R., Guzhova, Irina V., Margulis, Boris A.
Publicado 2017

Combination of Anti-Cancer Drugs with Molecular Chaperone Inhibitors

por Shevtsov, Maxim, Multhoff, Gabriele, Mikhaylova, Elena, Shibata, Atsushi, Guzhova, Irina, Margulis, Boris
Publicado 2019

The STIM1/2-Regulated Calcium Homeostasis Is Impaired in Hippocampal Neurons of the 5xFAD Mouse Model of Alzheimer’s Disease

por Skobeleva, Ksenia, Shalygin, Alexey, Mikhaylova, Elena, Guzhova, Irina, Ryazantseva, Maria, Kaznacheyeva, Elena
Publicado 2022

Carotenoids and Some Other Pigments from Fungi and Yeasts †

por Rapoport, Alexander, Guzhova, Irina, Bernetti, Lorenzo, Buzzini, Pietro, Kieliszek, Marek, Kot, Anna Maria
Publicado 2021

Hydrocortisone 21-hemisuccinate did not prevent exogenous GAPDH-induced apoptosis in human neuroblastoma cells

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Komarova, Elena Y., Guzhova, Irina V., Margulis, Boris A.
Publicado 2018

Protein Interactome of Amyloid-β as a Therapeutic Target

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Kanunikov, Igor E., Guzhova, Irina V., Margulis, Boris A.
Publicado 2023

Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress

por Mikeladze, Marina A., Dutysheva, Elizaveta A., Kartsev, Victor G., Margulis, Boris A., Guzhova, Irina V., Lazarev, Vladimir F.
Publicado 2021

The mTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy

por Alhasan, Bashar A., Gordeev, Sergei A., Knyazeva, Aleksandra R., Aleksandrova, Kseniia V., Margulis, Boris A., Guzhova, Irina V., Suvorova, Irina I.
Publicado 2021

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity

por Shevtsov, Maxim A., Komarova, Elena Y., Meshalkina, Darya A., Bychkova, Natalia V., Aksenov, Nikolai D., Abkin, Sergey V., Margulis, Boris A., Guzhova, Irina V.
Publicado 2014

Knock-down of Hdj2/DNAJA1 co-chaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells

por Meshalkina, Darya A., Shevtsov, Maxim A., Dobrodumov, Anatoliy V., Komarova, Elena Y., Voronkina, Irina V., Lazarev, Vladimir F., Margulis, Boris A., Guzhova, Irina V.
Publicado 2016

Indolylazine Derivative Induces Chaperone Expression in Aged Neural Cells and Prevents the Progression of Alzheimer’s Disease

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Mikhaylova, Elena R., Trestsova, Maria A., Utepova, Irina A., Chupakhin, Oleg N., Margulis, Boris A., Guzhova, Irina V.
Publicado 2022

Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells

por Nikotina, Alina D., Koludarova, Lidia, Komarova, Elena Y., Mikhaylova, Elena R., Aksenov, Nikolay D., Suezov, Roman, Kartzev, Viktor G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2018

Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons

por Dutysheva, Elizaveta A., Utepova, Irina A., Trestsova, Maria A., Anisimov, Alexander S., Charushin, Valery N., Chupakhin, Oleg N., Margulis, Boris A., Guzhova, Irina V., Lazarev, Vladimir F.
Publicado 2021

Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children

por Shevtsov, Maxim A, Kim, Alexander V, Samochernych, Konstantin A, Romanova, Irina V, Margulis, Boris A, Guzhova, Irina V, Yakovenko, Igor V, Ischenko, Alexander M, Khachatryan, William A
Publicado 2014

Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells

por Komarova, Elena Y., Marchenko, Larisa V., Zhakhov, Alexander V., Nikotina, Alina D., Aksenov, Nikolay D., Suezov, Roman V., Ischenko, Alexander M., Margulis, Boris A., Guzhova, Irina V.
Publicado 2019

Prevention of High Glucose-Mediated EMT by Inhibition of Hsp70 Chaperone

por Nikotina, Alina D., Vladimirova, Snezhana A., Komarova, Elena Y., Alexeev, Dmitry, Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G., Polonik, Sergey G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2021