HSP70-based anti-cancer immunotherapy

por Guzhova, Irina V., Margulis, Boris A.
Publicado 2016

Glyceraldehyde-3-phosphate Dehydrogenase Is a Multifaceted Therapeutic Target

por Lazarev, Vladimir F., Guzhova, Irina V., Margulis, Boris A.
Publicado 2020

Phospholipse c inhibitor, u73122, stimulates release of hsp-70 stress protein from A431 human carcinoma cells

por Evdonin, Anton L, Guzhova, Irina V, Margulis, Boris A, Medvedeva, Natalia D
Publicado 2004

Possible Function of Molecular Chaperones in Diseases Caused by Propagating Amyloid Aggregates

por Lazarev, Vladimir F., Mikhaylova, Elena R., Guzhova, Irina V., Margulis, Boris A.
Publicado 2017

Hydrocortisone 21-hemisuccinate did not prevent exogenous GAPDH-induced apoptosis in human neuroblastoma cells

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Komarova, Elena Y., Guzhova, Irina V., Margulis, Boris A.
Publicado 2018

Protein Interactome of Amyloid-β as a Therapeutic Target

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Kanunikov, Igor E., Guzhova, Irina V., Margulis, Boris A.
Publicado 2023

Disruption of the Complex between GAPDH and Hsp70 Sensitizes C6 Glioblastoma Cells to Hypoxic Stress

por Mikeladze, Marina A., Dutysheva, Elizaveta A., Kartsev, Victor G., Margulis, Boris A., Guzhova, Irina V., Lazarev, Vladimir F.
Publicado 2021

The mTOR Pathway in Pluripotent Stem Cells: Lessons for Understanding Cancer Cell Dormancy

por Alhasan, Bashar A., Gordeev, Sergei A., Knyazeva, Aleksandra R., Aleksandrova, Kseniia V., Margulis, Boris A., Guzhova, Irina V., Suvorova, Irina I.
Publicado 2021

Exogenously delivered heat shock protein 70 displaces its endogenous analogue and sensitizes cancer cells to lymphocytes-mediated cytotoxicity

por Shevtsov, Maxim A., Komarova, Elena Y., Meshalkina, Darya A., Bychkova, Natalia V., Aksenov, Nikolai D., Abkin, Sergey V., Margulis, Boris A., Guzhova, Irina V.
Publicado 2014

Knock-down of Hdj2/DNAJA1 co-chaperone results in an unexpected burst of tumorigenicity of C6 glioblastoma cells

por Meshalkina, Darya A., Shevtsov, Maxim A., Dobrodumov, Anatoliy V., Komarova, Elena Y., Voronkina, Irina V., Lazarev, Vladimir F., Margulis, Boris A., Guzhova, Irina V.
Publicado 2016

Indolylazine Derivative Induces Chaperone Expression in Aged Neural Cells and Prevents the Progression of Alzheimer’s Disease

por Lazarev, Vladimir F., Dutysheva, Elizaveta A., Mikhaylova, Elena R., Trestsova, Maria A., Utepova, Irina A., Chupakhin, Oleg N., Margulis, Boris A., Guzhova, Irina V.
Publicado 2022

Discovery and optimization of cardenolides inhibiting HSF1 activation in human colon HCT-116 cancer cells

por Nikotina, Alina D., Koludarova, Lidia, Komarova, Elena Y., Mikhaylova, Elena R., Aksenov, Nikolay D., Suezov, Roman, Kartzev, Viktor G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2018

Dataset of NMR-spectra pyrrolyl- and indolylazines and evidence of their ability to induce heat shock genes expression in human neurons

por Dutysheva, Elizaveta A., Utepova, Irina A., Trestsova, Maria A., Anisimov, Alexander S., Charushin, Valery N., Chupakhin, Oleg N., Margulis, Boris A., Guzhova, Irina V., Lazarev, Vladimir F.
Publicado 2021

Pilot study of intratumoral injection of recombinant heat shock protein 70 in the treatment of malignant brain tumors in children

por Shevtsov, Maxim A, Kim, Alexander V, Samochernych, Konstantin A, Romanova, Irina V, Margulis, Boris A, Guzhova, Irina V, Yakovenko, Igor V, Ischenko, Alexander M, Khachatryan, William A
Publicado 2014

Extracellular Hsp70 Reduces the Pro-Tumor Capacity of Monocytes/Macrophages Co-Cultivated with Cancer Cells

por Komarova, Elena Y., Marchenko, Larisa V., Zhakhov, Alexander V., Nikotina, Alina D., Aksenov, Nikolay D., Suezov, Roman V., Ischenko, Alexander M., Margulis, Boris A., Guzhova, Irina V.
Publicado 2019

Prevention of High Glucose-Mediated EMT by Inhibition of Hsp70 Chaperone

por Nikotina, Alina D., Vladimirova, Snezhana A., Komarova, Elena Y., Alexeev, Dmitry, Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G., Polonik, Sergey G., Margulis, Boris A., Guzhova, Irina V.
Publicado 2021

Marine Fungal Cerebroside Flavuside B Protects HaCaT Keratinocytes against Staphylococcus aureus Induced Damage

por Chingizova, Ekaterina A., Menchinskaya, Ekaterina S., Chingizov, Artur R., Pislyagin, Evgeny A., Girich, Elena V., Yurchenko, Anton N., Guzhova, Irina V., Mikhailov, Valery V., Aminin, Dmitry L., Yurchenko, Ekaterina A.
Publicado 2021

Combined Cytotoxic Effect of Inhibitors of Proteostasis on Human Colon Cancer Cells

por Nikotina, Alina D., Vladimirova, Snezhana A., Kokoreva, Nadezhda E., Komarova, Elena Y., Aksenov, Nikolay D., Efremov, Sergey, Leonova, Elizaveta, Pavlov, Rostislav, Kartsev, Viktor G., Zhang, Zhichao, Margulis, Boris A., Guzhova, Irina V.
Publicado 2022

Sensitizing tumor cells to conventional drugs: HSP70 chaperone inhibitors, their selection and application in cancer models

por Lazarev, Vladimir F., Sverchinsky, Dmitry V., Mikhaylova, Elena R., Semenyuk, Pavel I., Komarova, Elena Y., Niskanen, Sergey A., Nikotina, Alina D., Burakov, Anton V., Kartsev, Viktor G., Guzhova, Irina V., Margulis, Boris A.
Publicado 2018

Autocrine regulation of tumor cell repopulation by Hsp70-HMGB1 alarmin complex

por Sverchinsky, Dmitry V., Alhasan, Bashar A., Mikeladze, Marina A., Lazarev, Vladimir F., Kuznetcova, Liubov S., Morshneva, Alisa V., Nikotina, Alina D., Ziewanah, Amr, Koludarova, Lidia V., Starkova, Tatiana Y., Margulis, Boris A., Guzhova, Irina V.
Publicado 2023