Transcriptional profiling demonstrates altered characteristics of CD8 (+) cytotoxic T‐cells and regulatory T‐cells in TP53‐mutated acute myeloid leukemia

por Abolhalaj, Milad, Sincic, Viktor, Lilljebjörn, Henrik, Sandén, Carl, Aab, Alar, Hägerbrand, Karin, Ellmark, Peter, Borrebaeck, Carl A. K., Fioretos, Thoas, Lundberg, Kristina
Publicado 2022

Early Pharmacodynamic Changes Measured Using RNA Sequencing of Peripheral Blood from Patients in a Phase I Study with Mitazalimab, a Potent CD40 Agonistic Monoclonal Antibody

por Andersson, Hampus, Sobti, Aastha, Jimenez, David Gomez, de Coaña, Yago Pico, Ambarkhane, Sumeet Vijay, Hägerbrand, Karin, Smith, Karin Enell, Lindstedt, Malin, Ellmark, Peter
Publicado 2023

The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation

por Kvarnhammar, Anne Månsson, Veitonmäki, Niina, Hägerbrand, Karin, Dahlman, Anna, Smith, Karin Enell, Fritzell, Sara, von Schantz, Laura, Thagesson, Mia, Werchau, Doreen, Smedenfors, Kristine, Johansson, Maria, Rosén, Anna, Åberg, Ida, Winnerstam, Magnus, Nyblom, Eva, Barchan, Karin, Furebring, Christina, Norlén, Per, Ellmark, Peter
Publicado 2019

Bispecific antibodies targeting CD40 and tumor-associated antigens promote cross-priming of T cells resulting in an antitumor response superior to monospecific antibodies

por Hägerbrand, Karin, Varas, Laura, Deronic, Adnan, Nyesiga, Barnabas, Sundstedt, Anette, Ljung, Lill, Sakellariou, Christina, Werchau, Doreen, Thagesson, Mia, Gomez Jimenez, David, Greiff, Lennart, Celander, Mona, Smedenfors, Kristine, Rosén, Anna, Bölükbas, Deniz, Carlsson, Fredrika, Levin, Mattias, Säll, Anna, von Schantz, Laura, Lindstedt, Malin, Ellmark, Peter
Publicado 2022