The daunting complexity of cancer: understanding the battlefield is a step towards winning the war

por HANAHAN, Douglas
Publicado 2014

Cancer hallmarks intersect with neuroscience in the tumor microenvironment

por Hanahan, Douglas, Monje, Michelle
Publicado 2023

Loss of p19(Arf) Facilitates the Angiogenic Switch and Tumor Initiation in a Multi-Stage Cancer Model via p53-Dependent and Independent Mechanisms

por Ulanet, Danielle B., Hanahan, Douglas
Publicado 2010

The biology of personalized cancer medicine: Facing individual complexities underlying hallmark capabilities

por De Palma, Michele, Hanahan, Douglas
Publicado 2012

Genetic Deletion of the Desmosomal Component Desmoplakin Promotes Tumor Microinvasion in a Mouse Model of Pancreatic Neuroendocrine Carcinogenesis

por Chun, Matthew G. H., Hanahan, Douglas
Publicado 2010

Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer

por Cao, Zhu Alexander, Daniel, Dylan, Hanahan, Douglas
Publicado 2002

A set of microRNAs coordinately controls tumorigenesis, invasion, and metastasis

por Michael, Iacovos P., Saghafinia, Sadegh, Hanahan, Douglas
Publicado 2019

Functions of Paracrine PDGF Signaling in the Proangiogenic Tumor Stroma Revealed by Pharmacological Targeting

por Pietras, Kristian, Pahler, Jessica, Bergers, Gabriele, Hanahan, Douglas
Publicado 2008

Genetic Ablation of Bcl-x Attenuates Invasiveness without Affecting Apoptosis or Tumor Growth in a Mouse Model of Pancreatic Neuroendocrine Cancer

por Hager, Jeffrey H., Ulanet, Danielle B., Hennighausen, Lothar, Hanahan, Douglas
Publicado 2009

Carboplatin/paclitaxel, E7-vaccination and intravaginal CpG as tri-therapy towards efficient regression of genital HPV16 tumors

por Domingos-Pereira, Sonia, Galliverti, Gabriele, Hanahan, Douglas, Nardelli-Haefliger, Denise
Publicado 2019

Assessing Tumor Progression Factors by Somatic Gene Transfer into a Mouse Model: Bcl-xL Promotes Islet Tumor Cell Invasion

por Du, Yi-Chieh Nancy, Lewis, Brian C, Hanahan, Douglas, Varmus, Harold
Publicado 2007

Identification and Characterization of Poorly Differentiated Invasive Carcinomas in a Mouse Model of Pancreatic Neuroendocrine Tumorigenesis

por Hunter, Karen E., Quick, Marsha L., Sadanandam, Anguraj, Hanahan, Douglas, Joyce, Johanna A.
Publicado 2013

Immune Enhancement of Skin Carcinogenesis by CD4(+) T Cells

por Daniel, Dylan, Meyer-Morse, Nicole, Bergsland, Emily K., Dehne, Kerstin, Coussens, Lisa M., Hanahan, Douglas
Publicado 2003

Metabolic Symbiosis Enables Adaptive Resistance to Anti-angiogenic Therapy that Is Dependent on mTOR Signaling

por Allen, Elizabeth, Miéville, Pascal, Warren, Carmen M., Saghafinia, Sadegh, Li, Leanne, Peng, Mei-Wen, Hanahan, Douglas
Publicado 2016

Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity

por Chryplewicz, Agnieszka, Scotton, Julie, Tichet, Mélanie, Zomer, Anoek, Shchors, Ksenya, Joyce, Johanna A., Homicsko, Krisztian, Hanahan, Douglas
Publicado 2022

Differential Contribution to Neuroendocrine Tumorigenesis of Parallel Egfr Signaling in Cancer Cells and Pericytes

por Nolan-Stevaux, Olivier, Truitt, Morgan C., Pahler, Jessica C., Olson, Peter, Guinto, Cristina, Lee, David C., Hanahan, Douglas
Publicado 2010

Deficiency for the Cysteine Protease Cathepsin L Impairs Myc-Induced Tumorigenesis in a Mouse Model of Pancreatic Neuroendocrine Cancer

por Brindle, Nicola R., Joyce, Johanna A., Rostker, Fanya, Lawlor, Elizabeth R., Swigart-Brown, Lamorna, Evan, Gerard, Hanahan, Douglas, Shchors, Ksenya
Publicado 2015

Self Antigens Expressed by Solid Tumors Do Not Efficiently Stimulate Naive or Activated T Cells: Implications for Immunotherapy

por Speiser, Daniel E., Miranda, Renata, Zakarian, Arsen, Bachmann, Martin F., McKall-Faienza, Kim, Odermatt, Bernhard, Hanahan, Douglas, Zinkernagel, Rolf M., Ohashi, Pamela S.
Publicado 1997

GKAP Acts as a Genetic Modulator of NMDAR Signaling to Govern Invasive Tumor Growth

por Li, Leanne, Zeng, Qiqun, Bhutkar, Arjun, Galván, José A., Karamitopoulou, Eva, Noordermeer, Daan, Peng, Mei-Wen, Piersigilli, Alessandra, Perren, Aurel, Zlobec, Inti, Robinson, Hugh, Iruela-Arispe, M. Luisa, Hanahan, Douglas
Publicado 2018

Synaptic proximity enables NMDAR signaling to promote brain metastasis

por Zeng, Qiqun, Michael, Iacovos P., Zhang, Peng, Saghafinia, Sadegh, Knott, Graham, Jiao, Wei, McCabe, Brian D., Galván, José A., Robinson, Hugh P. C., Zlobec, Inti, Ciriello, Giovanni, Hanahan, Douglas
Publicado 2019