Xenotransplantation—A Basic Science Perspective

por Cooper, David K.C., Hara, Hidetaka
Publicado 2023

“You cannot stay in the laboratory forever”*: Taking pig kidney xenotransplantation from the laboratory to the clinic

por Cooper, David K.C., Hara, Hidetaka
Publicado 2021

Evidence for the important role of inflammation in xenotransplantation

por Li, Juan, Hara, Hidetaka, Wang, Yi, Esmon, Charles, Cooper, David K. C., Iwase, Hayato
Publicado 2019

Induction of diabetes in cynomolgus monkey with one shot of analytical grade streptozotocin

por Liu, Zhengzhao, Lu, Ying, Hu, Wenbao, Hara, Hidetaka, Dai, Yifan, Cai, Zhiming, Mou, Lisha
Publicado 2020

Circulating Organ-Specific MicroRNAs Serve as Biomarkers in Organ-Specific Diseases: Implications for Organ Allo- and Xeno-Transplantation

por Zhou, Ming, Hara, Hidetaka, Dai, Yifan, Mou, Lisha, Cooper, David K. C., Wu, Changyou, Cai, Zhiming
Publicado 2016

The potential of genetically-engineered pigs in providing an alternative source of organs and cells for transplantation

por Cooper, David K.C., Hara, Hidetaka, Ezzelarab, Mohamed, Bottino, Rita, Trucco, Massimo, Phelps, Carol, Ayares, David, Dai, Yifan
Publicado 2013

Effect of intravenous immunoglobulin (IVIg) on primate complement-dependent cytotoxicity of genetically engineered pig cells: relevance to clinical xenotransplantation

por Yamamoto, Takayuki, Cui, Yehua, Patel, Diyan, Jagdale, Abhijit, Iwase, Hayato, Ayares, David, Cooper, David K. C., Hara, Hidetaka
Publicado 2020

Evidence for GTKO/β4GalNT2KO Pigs as the Preferred Organ-source for Old World Nonhuman Primates as a Preclinical Model of Xenotransplantation

por Cui, Yehua, Yamamoto, Takayuki, Raza, Syed Sikandar, Morsi, Mahmoud, Nguyen, Huy Quoc, Ayares, David, Cooper, David K.C., Hara, Hidetaka
Publicado 2020

Attempted Depletion of Passenger Leukocytes by Irradiation in Pigs

por Tai, Hao-Chih, Zhu, Xiaocheng, Lin, Yih Jyh, Hara, Hidetaka, Ezzelarab, Mohamed, Epperley, Michael, Quader, Mubina A., Cooper, David K. C.
Publicado 2011

Old World Monkeys are less than ideal transplantation models for testing pig organs lacking three carbohydrate antigens (Triple-Knockout)

por Yamamoto, Takayuki, Iwase, Hayato, Patel, Diyan, Jagdale, Abhijit, Ayares, David, Anderson, Douglas, Eckhoff, Devin E., Cooper, David K. C., Hara, Hidetaka
Publicado 2020

Comparison of porcine corneal decellularization methods and importance of preserving corneal limbus through decellularization

por Isidan, Abdulkadir, Liu, Shaohui, Chen, Angela M., Zhang, Wenjun, Li, Ping, Smith, Lester J., Hara, Hidetaka, Cooper, David K. C., Ekser, Burcin
Publicado 2021

Profound thrombocytopenia associated with administration of multiple anti‐inflammatory agents in baboons

por Bikhet, Mohamed H., Hansen‐Estruch, Christophe, Javed, Mariyam, Collins, Dalis E., Foote, Jeremy B., Ayares, David, Hara, Hidetaka, Cooper, David K. C.
Publicado 2022

The Role of Interleukin-6 (IL-6) in the Systemic Inflammatory Response in Xenograft Recipients and in Pig Kidney Xenograft Failure

por Zhang, Guoqiang, Iwase, Hayato, Li, Qi, Yamamoto, Takayuki, Jagdale, Abhijit, Ezzelarab, Mohamed B., Ayares, David, Cooper, David K. C., Hara, Hidetaka, Wang, Gangcheng
Publicado 2021

Production of α1,3-galactosyltransferase and cytidine monophosphate-N-acetylneuraminic acid hydroxylase gene double-deficient pigs by CRISPR/Cas9 and handmade cloning

por GAO, Hanchao, ZHAO, Chengjiang, XIANG, Xi, LI, Yong, ZHAO, Yanli, LI, Zesong, PAN, Dengke, DAI, Yifan, HARA, Hidetaka, COOPER, David K.C., CAI, Zhiming, MOU, Lisha
Publicado 2016

Anti-Neu5Gc and anti-non-Neu5Gc antibodies in healthy humans

por Gao, Bingsi, Long, Cassandra, Lee, Whayoung, Zhang, Zhongqiang, Gao, Xiaotian, Landsittel, Doug, Ezzelarab, Mohamed, Ayares, David, Huang, Yuliang, Cooper, David K. C., Wang, Yi, Hara, Hidetaka
Publicado 2017

Genetically-Engineered Pig-to-Baboon Liver Xenotransplantation: Histopathology of Xenografts and Native Organs

por Ekser, Burcin, Klein, Edwin, He, Jing, Stolz, Donna B., Echeverri, Gabriel J., Long, Cassandra, Lin, Chih Che, Ezzelarab, Mohamed, Hara, Hidetaka, Veroux, Massimiliano, Ayares, David, Cooper, David K. C., Gridelli, Bruno
Publicado 2012

Human Hemangioblast-Derived Mesenchymal Stem Cells Promote Islet Engraftment in a Minimal Islet Mass Transplantation Model in Mice

por Bertera, Suzanne, Knoll, Michael F., Knoll, Carmela, Hara, Hidetaka, Kimbrel, Erin A., Kouris, Nickolas A., Lanza, Robert, Philips, Brett E., Garciafigueroa, Yesica, Giannoukakis, Nick, Cooper, David K. C., Trucco, Massimo, Bottino, Rita
Publicado 2021

Clinical Islet Xenotransplantation: How Close Are We?

por van der Windt, Dirk J., Bottino, Rita, Kumar, Goutham, Wijkstrom, Martin, Hara, Hidetaka, Ezzelarab, Mohamed, Ekser, Burcin, Phelps, Carol, Murase, Noriko, Casu, Anna, Ayares, David, Lakkis, Fadi G., Trucco, Massimo, Cooper, David K.C.
Publicado 2012

Potential Antigens Involved in Delayed Xenograft Rejection in a Ggta1/Cmah Dko Pig-to-Monkey Model

por Zhang, Junfang, Xie, Chongwei, Lu, Ying, Zhou, Ming, Qu, Zepeng, Yao, Da, Qiu, Chuanghua, Xu, Jia, Pan, Dengke, Dai, Yifan, Hara, Hidetaka, Cooper, David K. C., Ma, Shanshan, Li, Mingtao, Cai, Zhiming, Mou, Lisha
Publicado 2017

Data on B cell phenotypes in baboons with pig artery patch grafts receiving conventional immunosuppressive therapy

por Yamamoto, Takayuki, Li, Qi, Hara, Hidetaka, Wang, Liaoran, Zhou, Hongmin, Li, Juan, Eckhoff, Devin E., Tector, A. Joseph, Klein, Edwin C., Lovingood, Ray, Ezzelarab, Mohamed, Ayares, David, Wang, Yi, Cooper, David K.C., Iwase, Hayato
Publicado 2018