Design and evaluation of a novel flavonoid-based radioprotective agent utilizing monoglucosyl rutin

por Aizawa, Yasushi, Sunada, Shigeaki, Hirakawa, Hirokazu, Fujimori, Akira, Kato, Takamitsu A, Uesaka, Mitsuru
Publicado 2018

Monoenergetic 290 MeV/n carbon-ion beam biological lethal dose distribution surrounding the Bragg peak

por Buglewicz, Dylan J., Banks, Austin B., Hirakawa, Hirokazu, Fujimori, Akira, Kato, Takamitsu A.
Publicado 2019

High LET-Like Radiation Tracks at the Distal Side of Accelerated Proton Bragg Peak

por Horendeck, Dakota, Walsh, Kade D., Hirakawa, Hirokazu, Fujimori, Akira, Kitamura, Hisashi, Kato, Takamitsu A.
Publicado 2021

Palmitoyl ascorbic acid 2-glucoside has the potential to protect mammalian cells from high-LET carbon-ion radiation

por Haskins, Alexis H., Buglewicz, Dylan J., Hirakawa, Hirokazu, Fujimori, Akira, Aizawa, Yasushi, Kato, Takamitsu A.
Publicado 2018

Reduction of Delayed Homologous Recombination by Induction of Radioadaptive Response in RaDR-GFP Mice (Yonezawa Effect): An Old Player With a New Role

por Liu, Cuihua, Hirakawa, Hirokazu, Tanaka, Kaoru, Mohd Saaya, Fazliana, Nenoi, Mitsuru, Fujimori, Akira, Wang, Bing
Publicado 2019

Radiobiological Characterization of Canine Malignant Melanoma Cell Lines with Different Types of Ionizing Radiation and Efficacy Evaluation with Cytotoxic Agents

por Yoshikawa, Hiroto, Sunada, Shigeaki, Hirakawa, Hirokazu, Fujimori, Akira, Elmegerhi, Suad, Leary, Del, Kato, Takamitsu A.
Publicado 2019

Biological Effects of Monoenergetic Carbon Ions and Their Associated Secondary Particles

por Buglewicz, Dylan J., Walsh, Kade D., Hirakawa, Hirokazu, Kitamura, Hisashi, Fujimori, Akira, Kato, Takamitsu A.
Publicado 2022

Hsp90 inhibitor is a good candidate for effective combination therapy with carbon ions

por Okayasu, Ryuichi, Hirakawa, Hirokazu, Masaoka, Aya, Noguchi, Miho, Hirayama, Ryoichi, Li, Huizi, Matsumoto, Yoshitaka, Fujimori, Akira
Publicado 2014

The combination of Hsp90 inhibitor 17AAG and heavy-ion irradiation provides effective tumor control in human lung cancer cells

por Hirakawa, Hirokazu, Fujisawa, Hiroshi, Masaoka, Aya, Noguchi, Miho, Hirayama, Ryoichi, Takahashi, Momoko, Fujimori, Akira, Okayasu, Ryuichi
Publicado 2015

Altered Induction of Reactive Oxygen Species by X-rays in Hematopoietic Cells of C57BL/6-Tg (CAG-EGFP) Mice

por Liu, Cuihua, Hirakawa, Hirokazu, Katsube, Takanori, Fang, Yaqun, Tanaka, Kaoru, Nenoi, Mitsuru, Fujimori, Akira, Wang, Bing
Publicado 2021

Nontoxic concentration of DNA‐PK inhibitor NU7441 radio‐sensitizes lung tumor cells with little effect on double strand break repair

por Sunada, Shigeaki, Kanai, Hideki, Lee, Younghyun, Yasuda, Takeshi, Hirakawa, Hirokazu, Liu, Cuihua, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Publicado 2016

VE-821, an ATR inhibitor, causes radiosensitization in human tumor cells irradiated with high LET radiation

por Fujisawa, Hiroshi, Nakajima, Nakako Izumi, Sunada, Shigeaki, Lee, Younghyun, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Uesaka, Mitsuru, Okayasu, Ryuichi
Publicado 2015

Metal Ions Modify In Vitro DNA Damage Yields with High-LET Radiation

por Buglewicz, Dylan J., Su, Cathy, Banks, Austin B., Stenger-Smith, Jazmine, Elmegerhi, Suad, Hirakawa, Hirokazu, Fujimori, Akira, Kato, Takamitsu A.
Publicado 2023

Hyperthermia-induced radiosensitization in CHO wild-type, NHEJ repair mutant and HR repair mutant following proton and carbon-ion exposure

por MAEDA, JUNKO, FUJII, YOSHIHIRO, FUJISAWA, HIROSHI, HIRAKAWA, HIROKAZU, CARTWRIGHT, IAN M., UESAKA, MITSURU, KITAMURA, HISASHI, FUJIMORI, AKIRA, KATO, TAKAMITSU A.
Publicado 2015

DNA polymerase θ-mediated repair of high LET radiation-induced complex DNA double-strand breaks

por Yi, Geunil, Sung, Yubin, Kim, Chanwoo, Ra, Jae Sun, Hirakawa, Hirokazu, Kato, Takamitsu A, Fujimori, Akira, Kim, Hajin, Takata, Kei-ichi
Publicado 2023

High linear-energy-transfer radiation can overcome radioresistance of glioma stem-like cells to low linear-energy-transfer radiation

por Hirota, Yuki, Masunaga, Shin-Ichiro, Kondo, Natsuko, Kawabata, Shinji, Hirakawa, Hirokazu, Yajima, Hirohiko, Fujimori, Akira, Ono, Koji, Kuroiwa, Toshihiko, Miyatake, Shin-Ichi
Publicado 2014

Enhanced Effects of Chronic Restraint-Induced Psychological Stress on Total Body Fe-Irradiation-Induced Hematopoietic Toxicity in Trp53-Heterozygous Mice

por Wang, Bing, Katsube, Takanori, Tanaka, Kaoru, Ninomiya, Yasuharu, Hirakawa, Hirokazu, Liu, Cuihua, Maruyama, Kouichi, Varès, Guillaume, Kito, Seiji, Nakajima, Tetsuo, Fujimori, Akira, Nenoi, Mitsuru
Publicado 2022

DNA Repair Deficient Chinese Hamster Ovary Cells Exhibiting Differential Sensitivity to Charged Particle Radiation under Aerobic and Hypoxic Conditions

por Cartwright, Ian M., Su, Cathy, Haskins, Jeremy S., Salinas, Victoria A., Sunada, Shigeaki, Yu, Hao, Uesaka, Mitsuru, Hirakawa, Hirokazu, Chen, David J., Fujimori, Akira, Kato, Takamitsu A.
Publicado 2018

Reduced High-Dose Radiation-Induced Residual Genotoxic Damage by Induction of Radioadaptive Response and Prophylactic Mild Dietary Restriction in Mice

por Wang, Bing, Tanaka, Kaoru, Katsube, Takanori, Maruyama, Kouichi, Ninomiya, Yasuharu, Varès, Guillaume, Liu, Cuihua, Hirakawa, Hirokazu, Murakami, Masahiro, Fardous, Zeenath, Sultana, Nahida, Fujita, Kazuko, Fujimori, Akira, Nakajima, Tetsuo, Nenoi, Mitsuru
Publicado 2021