Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum

por CHALMERS, IAIN W., HOFFMANN, KARL F.
Publicado 2012

Characterization of the Schistosoma transcriptome opens up the world of helminth genomics

por Hoffmann, Karl F, Dunne, David W
Publicado 2004

Development and Validation of a Quantitative, High-Throughput, Fluorescent-Based Bioassay to Detect Schistosoma Viability

por Peak, Emily, Chalmers, Iain W., Hoffmann, Karl F.
Publicado 2010

Identification of Schistosoma mansoni gender-associated gene transcripts by cDNA microarray profiling

por Hoffmann, Karl F, Johnston, David A, Dunne, David W
Publicado 2002

Identification of 6-(piperazin-1-yl)-1,3,5-triazine as a chemical scaffold with broad anti-schistosomal activities

por Padalino, Gilda, Chalmers, Iain W., Brancale, Andrea, Hoffmann, Karl F.
Publicado 2020

Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni

por Padalino, Gilda, Ferla, Salvatore, Brancale, Andrea, Chalmers, Iain W., Hoffmann, Karl F.
Publicado 2018

Erratum to ‘Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni’ [IJP Drugs...

por Padalino, Gilda, Ferla, Salvatore, Brancale, Andrea, Chalmers, Iain W., Hoffmann, Karl F.
Publicado 2019

DISMISS: detection of stranded methylation in MeDIP-Seq data

por Niazi, Umar, Geyer, Kathrin K., Vickers, Martin J., Hoffmann, Karl F., Swain, Martin T.
Publicado 2016

Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature

por Coghlan, Avril, Padalino, Gilda, O'Boyle, Noel M., Hoffmann, Karl F., Berriman, Matthew
Publicado 2022

The Diterpenoid 7-Keto-Sempervirol, Derived from Lycium chinense, Displays Anthelmintic Activity against both Schistosoma mansoni and Fasciola hepatica

por Edwards, Jennifer, Brown, Martha, Peak, Emily, Bartholomew, Barbara, Nash, Robert J., Hoffmann, Karl F.
Publicado 2015

(Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach

por Cosseau, Céline, Wolkenhauer, Olaf, Padalino, Gilda, Geyer, Kathrin K., Hoffmann, Karl F., Grunau, Christoph
Publicado 2017

Using ChEMBL to Complement Schistosome Drug Discovery

por Padalino, Gilda, Coghlan, Avril, Pagliuca, Giampaolo, Forde-Thomas, Josephine E., Berriman, Matthew, Hoffmann, Karl F.
Publicado 2023

Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis

por Hai, Yang, Edwards, Jennifer E., Van Zandt, Michael C., Hoffmann, Karl F., Christianson, David W.
Publicado 2014

The Role of Interleukin (IL)-10 in the Persistence of Leishmania major in the Skin after Healing and the Therapeutic Potential of Anti–IL-10 Receptor Antibody for Sterile Cure

por Belkaid, Yasmine, Hoffmann, Karl F., Mendez, Susana, Kamhawi, Shaden, Udey, Mark C., Wynn, Tom A., Sacks, David L.
Publicado 2001

Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni

por Geyer, Kathrin K., Munshi, Sabrina E., Whiteland, Helen L., Fernandez-Fuentes, Narcis, Phillips, Dylan W., Hoffmann, Karl F.
Publicado 2018

The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation

por Crusco, Alessandra, Baptista, Rafael, Bhowmick, Sumana, Beckmann, Manfred, Mur, Luis A. J., Westwell, Andrew D., Hoffmann, Karl F.
Publicado 2019

Use of Genomic DNA as an Indirect Reference for Identifying Gender-Associated Transcripts in Morphologically Identical, but Chromosomally Distinct, Schistosoma mansoni Cercariae

por Fitzpatrick, Jennifer M., Protasio, Anna V., McArdle, Andrew J., Williams, Gary A., Johnston, David A., Hoffmann, Karl F.
Publicado 2008

Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene family

por Chalmers, Iain W, McArdle, Andrew J, Coulson, Richard MR, Wagner, Marissa A, Schmid, Ralf, Hirai, Hirohisa, Hoffmann, Karl F
Publicado 2008

Glycomic Analysis of Life Stages of the Human Parasite Schistosoma mansoni Reveals Developmental Expression Profiles of Functional and Antigenic Glycan Motifs

por Smit, Cornelis H., van Diepen, Angela, Nguyen, D. Linh, Wuhrer, Manfred, Hoffmann, Karl F., Deelder, André M., Hokke, Cornelis H.
Publicado 2015

Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni

por Craven, Holly M., Bonsignore, Riccardo, Lenis, Vasilis, Santi, Nicolo, Berrar, Daniel, Swain, Martin, Whiteland, Helen, Casini, Angela, Hoffmann, Karl F.
Publicado 2021