A Sweet Delivery for a Really Bitter Pill: Globo H and RNase 1

por Hosono, Masahiro
Publicado 2015

Transcriptomic alterations in malignant pleural mesothelioma cells in response to long-term treatment with bullfrog sialic acid-binding lectin

por Tatsuta, Takeo, Nakasato, Arisu, Sugawara, Shigeki, Hosono, Masahiro
Publicado 2021

Catfish Egg Lectin Enhances the Cytotoxicity of Sunitinib on Gb3-Expressing Renal Cancer Cells

por Ito, Jun, Sugawara, Shigeki, Tatsuta, Takeo, Hosono, Masahiro, Sato, Makoto
Publicado 2023

Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma

por Satoh, Toshiyuki, Tatsuta, Takeo, Sugawara, Shigeki, Hara, Akiyoshi, Hosono, Masahiro
Publicado 2017

Sialic acid-binding lectin from bullfrog eggs inhibits human malignant mesothelioma cell growth in vitro and in vivo

por Tatsuta, Takeo, Satoh, Toshiyuki, Sugawara, Shigeki, Hara, Akiyoshi, Hosono, Masahiro
Publicado 2018

Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme)

por TATSUTA, TAKEO, HOSONO, MASAHIRO, OGAWA, YUKIKO, INAGE, KYOKO, SUGAWARA, SHIGEKI, NITTA, KAZUO
Publicado 2014

Leczyme: A New Candidate Drug for Cancer Therapy

por Tatsuta, Takeo, Sugawara, Shigeki, Takahashi, Kohta, Ogawa, Yukiko, Hosono, Masahiro, Nitta, Kazuo
Publicado 2014

Cancer-Selective Induction of Apoptosis by Leczyme

por Tatsuta, Takeo, Sugawara, Shigeki, Takahashi, Kohta, Ogawa, Yukiko, Hosono, Masahiro, Nitta, Kazuo
Publicado 2014

RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells

por Kariya, Yukiko, Tatsuta, Takeo, Sugawara, Shigeki, Kariya, Yoshinobu, Nitta, Kazuo, Hosono, Masahiro
Publicado 2016

Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells

por TATSUTA, TAKEO, HOSONO, MASAHIRO, SUGAWARA, SHIGEKI, KARIYA, YUKIKO, OGAWA, YUKIKO, HAKOMORI, SENITIROH, NITTA, KAZUO
Publicado 2013

Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs

por TATSUTA, TAKEO, HOSONO, MASAHIRO, MIURA, YUKI, SUGAWARA, SHIGEKI, KARIYA, YUKIKO, HAKOMORI, SENITIROH, NITTA, KAZUO
Publicado 2013

Sialic Acid-Binding Lectin from Bullfrog Eggs Exhibits an Anti-Tumor Effect Against Breast Cancer Cells Including Triple-Negative Phenotype Cells

por Tatsuta, Takeo, Sato, Shoko, Sato, Toshiyuki, Sugawara, Shigeki, Suzuki, Tsuneyoshi, Hara, Akiyoshi, Hosono, Masahiro
Publicado 2018

Sialic acid-binding lectin (leczyme) induces apoptosis to malignant mesothelioma and exerts synergistic antitumor effects with TRAIL

por TATSUTA, TAKEO, HOSONO, MASAHIRO, TAKAHASHI, KOHTA, OMOTO, TAKASHI, KARIYA, YUKIKO, SUGAWARA, SHIGEKI, HAKOMORI, SENITIROH, NITTA, KAZUO
Publicado 2013

Potentiation of Epidermal Growth Factor-Mediated Oncogenic Transformation by Sialidase NEU3 Leading to Src Activation

por Yamamoto, Koji, Takahashi, Kohta, Shiozaki, Kazuhiro, Yamaguchi, Kazunori, Moriya, Setsuko, Hosono, Masahiro, Shima, Hiroshi, Miyagi, Taeko
Publicado 2015

Upregulation of sialidase NEU3 in head and neck squamous cell carcinoma associated with lymph node metastasis

por Shiga, Kiyoto, Takahashi, Kohta, Sato, Ikuro, Kato, Kengo, Saijo, Shigeru, Moriya, Setsuko, Hosono, Masahiro, Miyagi, Taeko
Publicado 2015

Increased sialidase activity in serum of cancer patients: Identification of sialidase and inhibitor activities in human serum

por Hata, Keiko, Tochigi, Tatsuo, Sato, Ikuro, Kawamura, Sadafumi, Shiozaki, Kazuhiro, Wada, Tadashi, Takahashi, Kohta, Moriya, Setsuko, Yamaguchi, Kazunori, Hosono, Masahiro, Miyagi, Taeko
Publicado 2015

Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge Halichondria okadai

por Matsumoto, Ryo, Fujii, Yuki, Kawsar, Sarkar M. A., Kanaly, Robert A., Yasumitsu, Hidetaro, Koide, Yasuhiro, Hasan, Imtiaj, Iwahara, Chihiro, Ogawa, Yukiko, Im, Chang Hun, Sugawara, Shigeki, Hosono, Masahiro, Nitta, Kazuo, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado 2012

A GM1b/asialo‐GM1 oligosaccharide‐binding R‐type lectin from purplish bifurcate mussels Mytilisepta virgata and its effect on MAP kinases

por Fujii, Yuki, Gerdol, Marco, Kawsar, Sarkar M. A., Hasan, Imtiaj, Spazzali, Francesca, Yoshida, Tatsusada, Ogawa, Yukiko, Rajia, Sultana, Kamata, Kenichi, Koide, Yasuhiro, Sugawara, Shigeki, Hosono, Masahiro, Tame, Jeremy R. H., Fujita, Hideaki, Pallavicini, Alberto, Ozeki, Yasuhiro
Publicado 2019

MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt’s Lymphoma Cells to Trigger Apoptosis through Multiple Pathways

por Hasan, Imtiaj, Sugawara, Shigeki, Fujii, Yuki, Koide, Yasuhiro, Terada, Daiki, Iimura, Naoya, Fujiwara, Toshiyuki, Takahashi, Keisuke G., Kojima, Nobuhiko, Rajia, Sultana, Kawsar, Sarkar M. A., Kanaly, Robert A., Uchiyama, Hideho, Hosono, Masahiro, Ogawa, Yukiko, Fujita, Hideaki, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado 2015

A Galactose-Binding Lectin Isolated from Aplysia kurodai (Sea Hare) Eggs Inhibits Streptolysin-Induced Hemolysis

por Hasan, Imtiaj, Watanabe, Miharu, Ishizaki, Naoto, Sugita-Konishi, Yoshiko, Kawakami, Yasushi, Suzuki, Jun, Dogasaki, Chikaku, Rajia, Sultana, Kawsar, Sarkar M. A., Koide, Yasuhiro, Kanaly, Robert A., Sugawara, Shigeki, Hosono, Masahiro, Ogawa, Yukiko, Fujii, Yuki, Iriko, Hideyuki, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado 2014